Altered colonic microflora and its metabolic profile in mice with acute viral myocarditis induced by coxsackievirus B3 [0.03%]
柯萨奇病毒B3诱导的小鼠急性病毒性心肌炎模型肠道菌群及其代谢谱的改变
Yimin Xue,Shirong Lin,Mingguang Chen et al.
Yimin Xue et al.
Mounting evidence suggests that the gut-heart axis is critical in the pathogenesis of cardiovascular diseases. The gut serves as the primary pathway through which Coxsackievirus B3 (CVB3) infects its host, leading to acute viral myocarditis...
Peripheral immune signatures associated with the risk of hepatocarcinogenesis in cirrhotic Egyptian HCV patients before and after treatment with direct-acting antivirals [0.03%]
慢性丙型肝炎患者抗病毒治疗前后来自外周免疫信号的肝癌发病风险标志物研究
Reem El-Shenawy,Rehab I Moustafa,Naiera M Helmy et al.
Reem El-Shenawy et al.
Background: Although direct-acting antivirals (DAAs) have revolutionized the management of chronic HCV, the debatable association with hepatocellular carcinoma (HCC) occurrence/recurrence has raised major concerns about t...
A humanized neutralizing antibody protects against human adenovirus type 7 infection in humanized desmoglein-2 and CD46 double-receptor transgenic mice [0.03%]
人源化中和抗体可通过靶向人双受体转基因小鼠中的血清型7的人腺病毒提供保护作用
Chengxing Zhou,Xiaohong Liao,Zhichao Zhou et al.
Chengxing Zhou et al.
Background: Human adenovirus type 7 (HAdV7) has become a major public health threat due to its widespread transmission, severe associated pneumonia, and a lack of effective anti-HAdV7 drugs. The aim of the current study i...
Comparative analysis of the epidemiological characteristics of adenovirus, rotavirus A, and coinfection in children during 2014-2023 in Guangzhou, China [0.03%]
2014-2023年广州市儿童人腺病毒、轮状病毒A和混合感染的流行病学特征比较分析
Yuqian Yan,Zhiwei Zeng,Huixin Gao et al.
Yuqian Yan et al.
Background: Infection is the cause of diarrhoea, and rotaviruses and adenoviruses are important pathogens in children. Methods: A retro...
Comparative Study
Virology journal. 2024 Nov 14;21(1):292. DOI:10.1186/s12985-024-02537-1 2024
Evaluation of the MAGLUMI HIV Ab/Ag combi test for the detection of HIV infection [0.03%]
评估梅里埃MAGLUMI HIV Ab/Ag联合检测试剂盒检测HIV感染的效果
Chunling Wang,Jie Rao,Zhonggang Fang et al.
Chunling Wang et al.
Background: Human immunodeficiency virus (HIV) infection screening and diagnosis are critical to control the HIV epidemic. Testing for anti-HIV antibodies (Ab) and antigens (Ag) in blood samples is the first step to scree...
Complete genome characterization by nanopore sequencing of rotaviruses A, B, and C circulating on large-scale pig farms in Russia [0.03%]
俄罗斯大规模猪场中轮转病毒A、B和C的全长基因组纳米孔测序表征
Nikita Krasnikov,Alexey Gulyukin,Taras Aliper et al.
Nikita Krasnikov et al.
Background: Rotaviruses are the major etiological agents of gastroenteritis and diarrheal outbreaks in plenty of mammalian species. The genus Rotavirus is highly diverse and currently comprises nine genetically distinct s...
Genomic epidemiology of early SARS-CoV-2 transmission dynamics in Bangladesh [0.03%]
孟加拉国早期新型冠状病毒传播动态的基因组流行病学研究
L Carnegie,J T McCrone,L du Plessis et al.
L Carnegie et al.
Background: Genomic epidemiology has helped reconstruct the global and regional movement of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there is still a lack of understanding of SARS-CoV-2 sprea...
HBeAg-positive CHB patients with indeterminate phase associated with a high risk of significant fibrosis [0.03%]
HBeAg阳性不确定期慢性乙型肝炎患者与显著纤维化高风险相关性研究
Yuanyuan Li,Yijia Zhu,Dongmei Gao et al.
Yuanyuan Li et al.
Background: The risk of liver fibrosis in HBeAg-positive chronic hepatitis B (CHB) patients with indeterminate phase is not well characterized. We aimed to compare the presence of liver fibrosis in HBeAg-positive CHB pati...
Multicenter Study
Virology journal. 2024 Nov 13;21(1):287. DOI:10.1186/s12985-024-02561-1 2024
Navigating SARS-CoV-2-related immunopathology in Crohn's disease: from molecular mechanisms to therapeutic challenges [0.03%]
克罗恩病中与SARS-CoV-2相关的免疫病理学：从分子机制到治疗挑战
Chang-Cyuan Chen,Yu-An Lin,Kuan-Ting Liu et al.
Chang-Cyuan Chen et al.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) not only posed major health and economic burdens to international societies but also threatens patients with comorbidities and underlying autoimmune disorders, including Crohn's d...
Identification of linear B cell epitopes on the E146L protein of African swine fever virus with monoclonal antibodies [0.03%]
非洲猪瘟病毒E146L蛋白的线性B细胞表位鉴定及其单克隆抗体识别表位研究
Shu-Jian Zhang,Bei Niu,Shi-Meng Liu et al.
Shu-Jian Zhang et al.
The outbreak and spread of African swine fever virus (ASFV) have caused considerable economic losses to the pig industry worldwide. Currently, to promote the development of effective ASF vaccines, especially subunit vaccines, more antigenic...