Mechanisms underlying the compromised clinical efficacy of interferon in clearing HBV [0.03%]
干扰素清除乙肝病毒临床疗效不佳的机制研究进展
Zhuoyan Lei,Luye Wang,Hanlin Gao et al.
Zhuoyan Lei et al.
Hepatitis B virus (HBV) is a hepatotropic DNA virus that can cause acute or chronic hepatitis, representing a significant global health concern. By 2019, approximately 296 million individuals were chronically infected with HBV, with 1.5 mil...
Evaluation of ALKBH2 and ALKBH3 gene regulation in patients with adult T-cell leukemia/lymphoma [0.03%]
成人T细胞白血病/淋巴瘤患者中ALKBH2和ALKBH3基因调控的评估
Yuji Wada,Tadasuke Naito,Takuya Fukushima et al.
Yuji Wada et al.
Background: Human T-cell leukemia virus type 1 (HTLV-1) is an oncogenic virus that causes malignant adult T-cell leukemia/lymphoma (ATL). Patients infected with HTLV-1 are considered HTLV-1 carriers, and a small proportio...
Research trends and hotspots on global influenza and inflammatory response based on bibliometrics [0.03%]
基于文献计量的全球流感及炎症反应研究趋势与热点分析
Hui Li,Yanping Zong,Jiajie Li et al.
Hui Li et al.
The influenza virus is considered as a kind of significant zoonotic infectious disease identified to date, with severe infections in humans characterized by excessive inflammation and tissue damage, usually resulting in serious complication...
Molecular characterization of circulating infectious bursal disease viruses in chickens from different Egyptian governorates during 2023 [0.03%]
2023年埃及不同省家鸡循环传染性法氏囊病病毒的分子特征分析
Amr H Abd El-Fatah,Dalia Ayman,Mahmoud Samir et al.
Amr H Abd El-Fatah et al.
Infectious bursal disease virus (IBDV) induces severe immunosuppression in chickens, leading to significant economic losses in the global poultry industry. This study investigated 52 chicken flocks, including commercial broilers, layers, an...
Integrating clinical data and genetic susceptibility to elucidate the relationship between systemic lupus erythematosus and human cytomegalovirus infection [0.03%]
整合临床数据和遗传易感性阐明系统性红斑狼疮与人类巨细胞病毒感染的关系
Xin Luo,Liuliu Quan,Qingting Lin et al.
Xin Luo et al.
Background: Viral infections are known to induce the occurrence and pathogenesis of systemic lupus erythematosus (SLE). Previous studies have indicated a possible relationship between SLE and human cytomegalovirus (HCMV) ...
Obtaining HBV core protein VLPs carrying SARS-CoV-2 nucleocapsid conserved fragments as vaccine candidates [0.03%]
获得携带SARS-CoV-2核衣壳保守片段的HBV核心蛋白VLP候选疫苗
Yadira Lobaina,Alexis Musacchio,Panchao Ai et al.
Yadira Lobaina et al.
The Hepatitis B core antigen (HBcAg) has been used as a carrier of several heterologous protein fragments based on its capacity to form virus-like particles (VLPs) and to activate innate and adaptive immune responses. In the present work, t...
Tomato yellow leaf curl virus (TYLCV) in Kuwait and global analysis of the population structure and evolutionary pattern of TYLCV [0.03%]
番茄黄化曲叶病毒(TYLCV)的科威特分离物和全球TYLCV种群结构及进化模式分析
Abrar Akbar,Hanadi Al Hashash,Ebtisam Al-Ali
Abrar Akbar
Tomato yellow leaf curl virus (Family Geminiviridae, Genus Begomovirus) is a serious menace in the cultivation of tomato causing Tomato leaf curl disease (ToLCD). Recently, we presented the TYLCV isolates having additional genomic features ...
Emilija Vasiliūnaitė,Monika Repšytė,Eva Marie Kramer et al.
Emilija Vasiliūnaitė et al.
Background: The garden dormouse (Eliomys quercinus) has experienced a significant population decline across Europe in recent decades. While habitat loss and climate change are often cited as primary factors, pathogen expo...
Genomic surveillance and evolutionary dynamics of influenza a virus in Sri Lanka [0.03%]
斯里兰卡的流感病毒基因组监测及进化动态
Tibutius Thanesh Pramanayagam Jayadas,Chandima Jeewandara,Bhagya Senadheera et al.
Tibutius Thanesh Pramanayagam Jayadas et al.
Background: Influenza A has been named as a priority pathogen by the WHO due to the potential to cause pandemics. Genomic sequencing of influenza strains is important to understand the evolution of the influenza strains a...
Multiple third-generation recombinants formed by CRF55_01B and CRF07_BC in newly diagnosed HIV-1 infected patients in Shenzhen city, China [0.03%]
中国深圳市新诊断HIV-1感染者中CRF55_01B与CRF07_BC重组形成的三代嵌合毒株广泛流行
Yan Jiao,Minghui An,Nan Zhang et al.
Yan Jiao et al.
In the evolution landscape of HIV, the coexistence of multiple subtypes has led to new, complex recombinants, posing public health challenges. CRF55_01B, first identified among MSM in Shenzhen, China, has spread rapidly across China. In thi...