The immunogenicity of PRV ΔgE/TK/UL49.5 three-gene-deleted vaccine in mice [0.03%]
伪狂犬病病毒三基因缺失弱毒活疫苗的免疫原性研究
Chenmeng Ding,Yawei Sun,Xianfeng Zhang et al.
Chenmeng Ding et al.
Background: Pseudorabies (PR) caused by the re-emerging of pseudorabies virus (PRV) variant has outbroken among PRV vaccine immunized swine in many pig farms, which has caused serious social and economic consequences sinc...
Advances in antiviral strategies targeting mosquito-borne viruses: cellular, viral, and immune-related approaches [0.03%]
针对蚊媒病毒的抗病毒策略研究进展：细胞、病毒及免疫相关方法
Ayyaz Khan,Zakirullah,Shahid Wahab et al.
Ayyaz Khan et al.
Mosquito-borne viruses (MBVs) are a major global health threat, causing significant morbidity and mortality. MBVs belong to several distinct viral families, each with unique characteristics. The primary families include Flaviviridae (e.g., ...
Development of a duplex real-time recombinase aided amplification assay for the simultaneous and rapid detection of PCV3 and PCV4 [0.03%]
一种同时快速检测PCV3和PCV4的双plex实时重组酶扩增检测方法的建立
Renjie Sun,Hanze Liu,Siqi Sun et al.
Renjie Sun et al.
Background: Porcine circoviruses 3 (PCV3) and 4 (PCV4) are emerging pathogens with global implications for swine industry, disturbing the diagnosis of PCVs associated diseases due to a range of similar clinical symptoms a...
A comparative analysis of sequence composition in different lots of a phage display peptide library during amplification [0.03%]
噬菌体肽展示文库扩增过程中不同批次序列组成比较分析
Anders Wilgaard Sinkjaer,Ane Beth Sloth,Amanda Oester Andersen et al.
Anders Wilgaard Sinkjaer et al.
Background: To develop efficient selection strategies and improve the discovery of promising ligands, it is highly desirable to analyze the sequence composition of naïve phage display libraries and monitor the evolution ...
Comparative Study
Virology journal. 2025 Feb 1;22(1):24. DOI:10.1186/s12985-024-02600-x 2025
Advances in bioinformatics and multi-omics integration: transforming viral infectious disease research in veterinary medicine [0.03%]
兽医医学中生物信息学和多组学整合的进展：转化病毒传染病研究
Alyaa Elrashedy,Walid Mousa,Mohamed Nayel et al.
Alyaa Elrashedy et al.
The world is changing due to factors like bioterrorism, massive environmental changes, globalization of trade and commerce, growing urbanization, changing climate, and pollution. Numerous diseases have emerged because of these factors, espe...
Characterization and genome analysis of lytic Vibrio phage VPK8 with potential in lysing Vibrio parahaemolyticus isolates from clinical and seafood sources [0.03%]
一种用于裂解临床及海鲜来源的副溶血性弧菌分离株的裂解型维氏噬菌体VPK8的表征及其基因组分析
Valalak Jintasakul,Jiranan Pattano,Sutima Preeprem et al.
Valalak Jintasakul et al.
Background: Vibrio parahaemolyticus is a marine bacterium causing seafood-associated gastrointestinal illness in humans and acute hepatopancreatic necrosis disease (AHPND) in shrimp. Bacteriophages have emerged as promisi...
Deciphering the therapeutic effects of Xiyanping injection: insights into pulmonary and gut microbiome modulation, SerpinB2/PAI-2 targeting, and alleviation of influenza a virus-induced lung injury [0.03%]
解码西雅平注射液的药理作用：肺和肠道菌群调节、SerpinB2/PAI-2靶向及缓解A型流感病毒所致肺损伤
Tengwen Liu,Shuping Li,Xuerui Wang et al.
Tengwen Liu et al.
Infection with Influenza A virus (IAV) induces severe inflammatory responses and lung injury, contributing significantly to mortality and morbidity rates. Alterations in the microbial composition of the lungs and intestinal tract resulting ...
C-28 linker length modulates the activity of second-generation HIV-1 maturation inhibitors [0.03%]
C-28连接臂长度调节第二代HIV-1成熟抑制剂的活性
K C Yuvraj,Aradhana Singh,Sayantani Datta et al.
K C Yuvraj et al.
Maturation inhibitors (MIs) block HIV-1 maturation by preventing the cleavage of the capsid protein and spacer peptide 1 (CA-SP1). Bevirimat (BVM), a first-in-class MI, displayed sub-optimal efficacy in clinical trials due to presence of SP...
Detection of human noroviruses in sewage by next generation sequencing in Shandong Province, 2019-2021 [0.03%]
山东省2019-2021年污水中诺如病毒的监测（基于下一代测序技术）
Suting Wang,Mingyi Xu,Xiaojuan Lin et al.
Suting Wang et al.
Background: Human noroviruses are the major cause of acute gastroenteritis and exhibit considerable genetic diversity. Next generation sequencing (NGS) analysis based on environmental surveillance has been proved to be an...
Multiple gene-deletion vaccinia virus Tiantan strain against mpox [0.03%]
TianTan株改良型安卡拉痘苗候选疫苗毒种TATV598
Yilong Zhu,Dapeng Li,Renshuang Zhao et al.
Yilong Zhu et al.
Monkeypox virus (MPXV) is an important zoonotic pathogenic virus, which poses serious threats to public health. MPXV infection can be prevented by immunization against the variola virus. Because of the safety risks and side effects of vacci...