Diverse effects of coronavirus-defective viral genomes on the synthesis of IFNβ and ISG15 mRNAs and coronavirus replication [0.03%]
缺陷病毒基因组对冠状病毒IFNβ和ISG15 mRNA合成及复制的多样性影响
Hsuan-Wei Hsu,Li-Kang Chang,Chun-Chun Yang et al.
Hsuan-Wei Hsu et al.
Background: The mechanism by which coronavirus-defective viral genomes (DVGs) affect coronavirus and host cells during infection remains unclear. A variety of DVGs with different RNA structures can be synthesized from cor...
A surrogate in vitro experimental model for off-label drug repurposing: inhibitory effect of montelukast on bovine respiratory syncytial virus replication [0.03%]
一种用于药物超适应症重新定位的体外实验模型：蒙特鲁克对牛呼吸道合胞病毒复制的抑制作用
Hanne Nur Kurucay,Zafer Yazici,Vahide Bayrakal et al.
Hanne Nur Kurucay et al.
Background: Repurposing off-label drugs during epidemics or pandemics with unknown/known pathogens, particularly when their side effects and complications are already known, can be a strategic approach, as seen during the...
Unexpected HBsAg decrease after nucleoside analogues retreatment among HBeAg positive postpartum women: a pilot study [0.03%]
核苷类似物再治疗导致的HBeAg阳性产后女性HBsAg意外下降：初步研究
Qiao Tang,Chunrui Wang,Hu Li et al.
Qiao Tang et al.
Background: Mother-to-child transmission (MTCT) is one of the main routes of transmission of HBV, and previous studies focused on the efficacy and safety of nucleoside analogues (NAs) in preventing MTCT. There are limited...
Genetic variations and carcinogenicity analysis of E6/E7 oncogenes in HPV31 and HPV35 in Taizhou, China [0.03%]
中国泰州市HPV31和HPV35的E6/E7原癌基因的遗传变异及致癌性分析
Hao-Bo Yuan,Jun-Hui Yu,Jun Gan et al.
Hao-Bo Yuan et al.
Background: The purpose of this study was to investigate the genetic variations in the E6 and E7 oncogenes of HPV31 and HPV35, and to explore their potential role in cervical cancer risk among women in Taizhou, China. ...
Outcomes of switching from protease inhibitor-based antiretroviral therapy to bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) in virologically suppressed adults with nucleos(t)ide analogue resistance- a phase IV randomised, open-label study (PIBIK study) [0.03%]
关于简化抗逆转录病毒疗法(PiBK研究):一项IV期、开放标签、随机对照研究
Collins Iwuji,Laura Waters,Ana Milinkovic et al.
Collins Iwuji et al.
Background: There are limited data on how historical nucleoside reverse transcriptase inhibitor (NRTI) resistance-associated mutations (RAMs) other than M184V/I, affect the activity of B/F/TAF. We evaluated the outcomes o...
Clinical Trial
Virology journal. 2025 Feb 10;22(1):33. DOI:10.1186/s12985-025-02648-3 2025
Clinical and molecular analysis of JCPyV and BKPyV infection and associated risk of urothelial carcinoma development in the upper tract [0.03%]
JC病毒和BK病毒的临床和分子分析及其与上尿路尿路上皮癌发生风险的相关性研究
Chun-Nun Chao,Chi-Feng Hung,Wei-Hong Lai et al.
Chun-Nun Chao et al.
Background: Human polyomaviruses (HPyVs), JC polyomavirus (JCPyV) and BK polyomavirus (BKPyV), have been found in upper tract urothelial carcinoma UTUC; however, the association of the viral oncogenic factors and clinical...
Standardization, validation, and comparative evaluation of a convenient surrogate recombinant vesicular stomatitis virus plaque reduction test for quantification of Hantaan orthohantavirus (HTNV) neutralizing antibodies [0.03%]
简便的替代重组粘液病毒噬斑减少试验的标准制定、验证及比较评价以定量汉坦正汉他病毒（HTNV）中和抗体
Jing Wei,Hui Zhang,Jiawei Pei et al.
Jing Wei et al.
Hantaan orthohantavirus (HTNV) is responsible for severe hemorrhagic fever with renal syndrome (HFRS), which has a case fatality rate of 1% to 10%. Currently, the inactive vaccine licensed in endemic areas elicit low levels of neutralizing ...
Comparative Study
Virology journal. 2025 Feb 8;22(1):31. DOI:10.1186/s12985-024-02613-6 2025
Association between cadherin-related family member 3 rs6967330-A and human rhinovirus-C induced wheezing in children [0.03%]
黏附分子CADM3基因多态性与儿童人鼻病毒C型感染相关喘息表型的作用研究
Hanhaoyu Fu,Ri De,Yu Sun et al.
Hanhaoyu Fu et al.
Background: The heterogeneity of childhood wheezing illnesses is associated with viral and host factors. Human rhinoviruses (HRV) are the major pathogens in severe wheezing in young children. The single nucleotide polymor...
First detection and molecular characterization of porcine epidemic diarrhea virus (PEDV) in India: evidence of a new variant in Karnataka [0.03%]
猪流行性腹泻病毒(PEDV)在印度的首次检测及分子特性分析：卡纳塔克邦新毒株证据
Jagadish B Hiremath,M Swathi,R Ramamoorthy et al.
Jagadish B Hiremath et al.
Background: Porcine epidemic diarrhea (PED) is a significant pig disease causing high mortality in suckling pigs and high morbidity across all age groups. It is highly prevalent in Southeast Asia, posing a threat of trans...
A ribodepletion and tagging protocol to multiplex samples for RNA-seq based virus detection: application to the cassava virome [0.03%]
一种用于RNA测序的病毒检测的样本复用的核糖体脱除和标记方法：在木薯病毒组中的应用
Daniel H Otron,Justin S Pita,Murielle Hoareau et al.
Daniel H Otron et al.
Background: Cassava (Manihot esculenta, Crantz), is a staple food and the main source of calories for many populations in Africa, but the plant is beset by several damaging viruses. So far, eight families of virus infecti...