Cyanide Beyond Toxicity: A Systematic Review of Its Effects on Vascular Function [0.03%]
氰化物与血管功能：系统性回顾超毒性作用之外的功能
Elif Alan-Albayrak,Ulf Simonsen
Elif Alan-Albayrak
Cyanide is widely recognized for its potent toxicity, yet evidence shows that concentrations below 1 μM may enhance cytochrome c oxidase activity and have a regulatory function. Recent findings also demonstrate that mammalian cells, includ...
Association of HLA-B*53 With DRESS Syndrome in Patients Treated With Raltegravir: Two Case Reports and a Literature Review [0.03%]
人类白细胞抗原B*53与拉替拉韦治疗患者的药物反应综合征关联性研究：2例报告及文献复习
Cristina Ramos-Del Moral,Pablo Rodríguez Cortés,Marcos Navares-Gómez et al.
Cristina Ramos-Del Moral et al.
Introduction: Raltegravir, an HIV integrase inhibitor, although generally well tolerated, may cause severe reactions such as drug reaction with eosinophilia and systemic symptoms (DRESS). This syndrome has been associated...
The Incidence of Benzodiazepine and Benzodiazepine-Related Drug Use in People With and Without Parkinson's Disease-A Nationwide Cohort Study [0.03%]
苯二氮卓类和苯二氮卓相关药物在帕金森病患者和非帕金森病患者中的使用情况——一项全国性队列研究
Veera Lonka,Sirpa Hartikainen,Miia Tiihonen et al.
Veera Lonka et al.
Background: Non-motor symptoms of Parkinson's disease (PD), including sleep problems and anxiety, are common and can appear before motor symptoms. Benzodiazepines and benzodiazepine-related drugs (BZDR) may be used to tre...
Doctor-Patient Deprescribing Conversations: A Multidisciplinary Analysis of Quality Assurance Recordings [0.03%]
医患减药谈话：质量保证记录的多学科分析
Kelly E Tenzek,Huei-Yen Winnie Chen,Laura A Brady et al.
Kelly E Tenzek et al.
Previous work in deprescribing interactions primarily involved surveys, interviews or reviews; there is a gap in utilizing real-time doctor-patient communication to understand what strategies physicians use to deprescribe and how patients r...
Bei Yang,Jie Liu
Bei Yang
As a replacement for phased-out perfluorooctanoic acid (PFOA), hexafluoropropylene oxide trimer carboxylic acid (HFPO-TA) exhibits environmental persistence and multisystem toxicity, affecting reproductive, hepatic, neurological and endocri...
Multidimensional Evaluation of Lisdexamfetamine: Pharmacology, Therapeutic Use, Toxicity and Forensic Implications [0.03%]
利斯德明的多维度评估：药理学、治疗应用、毒性和法医意义
Mariana Silva-Carvalho,Daniel José Barbosa,Diana Dias da Silva et al.
Mariana Silva-Carvalho et al.
Lisdexamfetamine (LDX), a prodrug of d-amphetamine, is widely used in the pharmacological treatment of neuropsychiatric disorders such as attention-deficit/hyperactivity disorder (ADHD) and binge eating disorder (BED). Chemically, it consis...
Metabolomics and Network Pharmacology Revealed the Mechanism of Feining Mixture Against Respiratory Syncytial Virus Pneumonia [0.03%]
代谢组学和网络药理学揭示了肺宁合剂抗呼吸道合胞病毒肺炎的机制研究
Chengdou Xie,Qianyu Liu,Ping Lan et al.
Chengdou Xie et al.
Respiratory syncytial virus (RSV) is a leading etiological agent of pneumonia, particularly affecting infants under 2 years and elderly populations, with characteristic clinical manifestations including fever, cough and wheezing. Although F...
Correction to "Capillary Sampling Enables Venetoclax Concentration Measurement in Acute Myeloid Leukaemia Within Academic Multicentre Trial" [0.03%]
对“毛细血管采样可在急性髓系白血病学界多中心试验中测量维奈克拉浓度”的修正
Published Erratum
Basic & clinical pharmacology & toxicology. 2025 Oct;137(4):e70120. DOI:10.1111/bcpt.70120 2025
Hesperidin Mitigates Bleomycin-Induced Testicular and Spermatological Damage in Rats [0.03%]
hesperidin对大鼠bleomycin致睾丸及生精毒性损伤的保护作用
İdris Ayhan,Nese Basak Turkmen,Saadet Alan et al.
İdris Ayhan et al.
Bleomycin (BLM), a chemotherapeutic agent commonly used in cancer treatment, is associated with oxidative stress and testicular toxicity, leading to impaired reproductive health. Hesperidin (HES), a citrus-derived flavonoid with strong anti...
Development of an Artificial Intelligence Powered Medication Risk Score Calculator Application [0.03%]
人工智能驱动的药物风险评分计算应用程序的研发
Ádám Bertalan,Viola Angyal,Péter Domján et al.
Ádám Bertalan et al.
The publication explores the development of the Augmented Medication Risk Score (AUGMERIS) calculator, a web application supported by artificial intelligence, designed to automate the evaluation of medication therapies with the Danish Medic...