How Is Psychotropic Use for Challenging Behaviour in People With Intellectual Disability Understood by Stakeholders? A Concept Analysis Using Rodgers' Evolutionary Approach [0.03%]
利益方是如何理解智力障碍人士挑战性行为的精神活性物质使用问题？一种运用Rodgers进化方法的概念分析
Dervla Kelly,Susan Morrissey,Darragh O&#x;Regan et al.
Dervla Kelly et al.
Psychotropic use for challenging behaviours in people with intellectual disability persists despite initiatives and prescribing guidelines encouraging judicious use. The use of some medications, such as psychiatric medications, can be stigm...
Insights Into Pharmacist-Led Deprescribing of Benzodiazepines and Related Drugs: A Qualitative Study With Physicians and Pharmacists [0.03%]
药师主导的苯二氮卓类和相关药物去处方的见解：与医师和药师的定性研究
Miro Korppas,Miia Tiihonen,Marika Buch Lund et al.
Miro Korppas et al.
While deprescribing benzodiazepines and related drugs (BZRDs) is crucial for preventing prolonged use and their associated adverse effects, it presents challenges from a healthcare perspective, because of limited resources and time. Recentl...
Pleural Effusion Formation Linked to Altered Transporter Expression Involved in Alveolar Fluid Clearance: Insights From the Monocrotaline Model of Pulmonary Hypertension [0.03%]
与参与肺液清除的转运蛋白表达改变相关的胸腔积液形成：来自单腹特碱诱导肺动脉高压模型的启示
Katarina Lelkova,Katarina Hadova,Michaela Katanova et al.
Katarina Lelkova et al.
Pleural effusions (PLEF) in pulmonary arterial hypertension (PAH), particularly in patients with isolated right heart failure, are associated with poor prognosis and increased mortality. This study investigates changes in alveolar fluid cle...
Emerging Molecular Targets in Neurodegenerative Disorders: New Avenues for Therapeutic Intervention [0.03%]
神经退行性疾病中新兴的分子靶点：治疗干预的新途径
Ezgi Eroglu,Nusin Harmanci
Ezgi Eroglu
Neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis and frontotemporal dementia represent a significant global health burden with limited therapeutic options. Cur...
Ocular Antibiotic Use in Young Danish Children From 2016 to 2024 [0.03%]
2016年至2024年丹麦年轻儿童的眼部抗生素使用情况
Heidi Sonne,Anton Pottegård,Katrine Sommerlund et al.
Heidi Sonne et al.
Kanika Rathi,Sakshi Sharma,Anil Barnwal
Kanika Rathi
Early detection of diseases is a critical pillar in advancing modern healthcare, offering timely interventions and better patient outcomes. This overview highlights a range of machine learning (ML) approaches that are transforming early dis...
Tools for Evaluating Potentially Inappropriate Medication Use in Older Adults: A Scoping Review Assessing Suitability for Register-Based Research [0.03%]
评估老年人潜在不适当用药的工具：适合基于登记册研究的适宜性系统综述
Katrine Mose,Carina Lundby,Lotte Rasmussen et al.
Katrine Mose et al.
This scoping review provides an overview of tools used to assess potentially inappropriate prescribing among older adults and discusses their suitability for register-based research. We performed a systematic search using PubMed (March 2024...
Barriers to and Enablers of Supporting Deprescribing Benzodiazepines in Older Adults: A Survey of European Nonphysician Healthcare Professionals [0.03%]
欧洲非医师医疗保健专业人员支持老年人停用苯二氮卓类药物的障碍与促进因素：一项调查研究
Vladyslav Shapoval,Perrine Evrard,François-Xavier Sibille et al.
Vladyslav Shapoval et al.
Although physicians are primarily responsible for Benzodiazepine Receptor Agonist (BZRA) deprescribing, nonphysician healthcare professionals (HCPs) can support deprescribing. This study explored barriers to and enablers of BZRA deprescribi...
Deprescribing Anticholinergic Medications in Hospitalised Older Adults: A Systematic Review [0.03%]
老年住院患者抗胆碱能药物的减药处方：系统评价研究
Rhianna Griffiths,Steve Lim,Julian Lin et al.
Rhianna Griffiths et al.
Background: Anticholinergic medication use is increasing, particularly among older adults due to polypharmacy and comorbidities. High anticholinergic burden is linked to adverse outcomes such as reduced mobility and incre...
Computer-Assisted Screening of Active Compounds in Traditional Chinese Medicine Targeting SNX10 as a Promising Treatment for Inflammatory Bowel Diseases [0.03%]
计算辅助筛选针对SNX10的中药活性成分用于治疗炎症性肠病
Yongpan An,Bowen Zhang,Yuwei Ye et al.
Yongpan An et al.
Inflammatory bowel diseases (IBD) are chronic and recurrent gastrointestinal disorders affecting millions worldwide, imposing significant social and economic burdens. Safe and effective medications for IBD prevention and treatment are urgen...