Exploration of Perceptions of Deprescribing Practices Among Doctors in a Low- and Middle-Income Country: A Mixed-Methods Study [0.03%]
一项混合方法研究：低收入和中等收入国家医生对减药做法认知的探索
Anjan Khadka,Sammodavardhana Kaundinnyayana,Kumar Roka et al.
Anjan Khadka et al.
With the increasing prevalence of potentially inappropriate medications in low- and middle-income countries (LMICs) like Nepal, the role of deprescribing is ever important. However, evidence on how Nepalese doctors perceive deprescribing in...
Saad Hanif Abbasi,Jesper Hallas,Peter Bjødstrup Jensen et al.
Saad Hanif Abbasi et al.
The type of prescriber typically fulfils the criteria for confounding, as it is associated both with the exposure (e.g., prescriber types may differ in their choice of first-line treatment) and with the outcome (as different types of prescr...
Adherence in the Treatment of Inflammatory Bowel Disease With Particular Focus on the Importance of the Clinical Pharmacist: A Systematic Review [0.03%]
炎症性肠病治疗的依从性：临床药师重要性的系统评价综述
Faria Sayed,Mark Andrew Ainsworth
Faria Sayed
Background: The prevalence of inflammatory bowel disease (IBD) is increasing. While several studies have shown that incorporating a clinical pharmacist into patient care can improve quality of life, evidence specifically ...
Cyanide Beyond Toxicity: A Systematic Review of Its Effects on Vascular Function [0.03%]
氰化物与血管功能：系统性回顾超毒性作用之外的功能
Elif Alan-Albayrak,Ulf Simonsen
Elif Alan-Albayrak
Cyanide is widely recognized for its potent toxicity, yet evidence shows that concentrations below 1 μM may enhance cytochrome c oxidase activity and have a regulatory function. Recent findings also demonstrate that mammalian cells, includ...
Association of HLA-B*53 With DRESS Syndrome in Patients Treated With Raltegravir: Two Case Reports and a Literature Review [0.03%]
人类白细胞抗原B*53与拉替拉韦治疗患者的药物反应综合征关联性研究：2例报告及文献复习
Cristina Ramos-Del Moral,Pablo Rodríguez Cortés,Marcos Navares-Gómez et al.
Cristina Ramos-Del Moral et al.
Introduction: Raltegravir, an HIV integrase inhibitor, although generally well tolerated, may cause severe reactions such as drug reaction with eosinophilia and systemic symptoms (DRESS). This syndrome has been associated...
The Incidence of Benzodiazepine and Benzodiazepine-Related Drug Use in People With and Without Parkinson's Disease-A Nationwide Cohort Study [0.03%]
苯二氮卓类和苯二氮卓相关药物在帕金森病患者和非帕金森病患者中的使用情况——一项全国性队列研究
Veera Lonka,Sirpa Hartikainen,Miia Tiihonen et al.
Veera Lonka et al.
Background: Non-motor symptoms of Parkinson's disease (PD), including sleep problems and anxiety, are common and can appear before motor symptoms. Benzodiazepines and benzodiazepine-related drugs (BZDR) may be used to tre...
Doctor-Patient Deprescribing Conversations: A Multidisciplinary Analysis of Quality Assurance Recordings [0.03%]
医患减药谈话：质量保证记录的多学科分析
Kelly E Tenzek,Huei-Yen Winnie Chen,Laura A Brady et al.
Kelly E Tenzek et al.
Previous work in deprescribing interactions primarily involved surveys, interviews or reviews; there is a gap in utilizing real-time doctor-patient communication to understand what strategies physicians use to deprescribe and how patients r...
Bei Yang,Jie Liu
Bei Yang
As a replacement for phased-out perfluorooctanoic acid (PFOA), hexafluoropropylene oxide trimer carboxylic acid (HFPO-TA) exhibits environmental persistence and multisystem toxicity, affecting reproductive, hepatic, neurological and endocri...
Multidimensional Evaluation of Lisdexamfetamine: Pharmacology, Therapeutic Use, Toxicity and Forensic Implications [0.03%]
利斯德明的多维度评估：药理学、治疗应用、毒性和法医意义
Mariana Silva-Carvalho,Daniel José Barbosa,Diana Dias da Silva et al.
Mariana Silva-Carvalho et al.
Lisdexamfetamine (LDX), a prodrug of d-amphetamine, is widely used in the pharmacological treatment of neuropsychiatric disorders such as attention-deficit/hyperactivity disorder (ADHD) and binge eating disorder (BED). Chemically, it consis...
Metabolomics and Network Pharmacology Revealed the Mechanism of Feining Mixture Against Respiratory Syncytial Virus Pneumonia [0.03%]
代谢组学和网络药理学揭示了肺宁合剂抗呼吸道合胞病毒肺炎的机制研究
Chengdou Xie,Qianyu Liu,Ping Lan et al.
Chengdou Xie et al.
Respiratory syncytial virus (RSV) is a leading etiological agent of pneumonia, particularly affecting infants under 2 years and elderly populations, with characteristic clinical manifestations including fever, cough and wheezing. Although F...