Maternal Exposure to Medications and the Risk of Congenital and Early-Onset Hearing Loss in Children: A Systematic Review and a Meta-Analysis [0.03%]
母亲用药与儿童先天性和婴儿期听力损失风险的相关性：系统评价和 meta 分析
Asli Sena Kücükyildiz,Mette Østergaard Thunbo,Christer Zøylner Swan et al.
Asli Sena Kücükyildiz et al.
Background: Congenital hearing loss (CHL) affects approximately 1-2 in 1000 children and significantly impacts development. Exposure to medications during pregnancy may impact offspring hearing; however, the ototoxic effe...
Development of a Deprescribing Intervention for Proton Pump Inhibitors in Primary Care: A Co-Design Approach With General Practitioners and Patients [0.03%]
与全科医生和患者共同设计开发 primary care中 proton pump inhibitors的减药干预措施
Kristie Rebecca Weir,Clémentine Tombez,Yvonne Mattmann et al.
Kristie Rebecca Weir et al.
Proton Pump Inhibitors (PPIs) are widely prescribed medications globally. PPIs are often inappropriately used - for example, prescribed without a clear indication, at higher-than-necessary doses, or for longer durations than needed - result...
Discontinuing Chronic Medications Suggested for Deprescribing in Routine Clinical Practice: Nationwide Evidence From Routinely Collected Data in Swedish Older Adults [0.03%]
来自瑞典老年人常规收集数据的全国证据：建议停止常规临床实践中慢性药物的长期使用
Karl-Hermann Sielinou Kamgang,Carina Lundby,Máté Szilcz et al.
Karl-Hermann Sielinou Kamgang et al.
Background: National estimates of drug discontinuation for deprescribing targets in older adults are limited, partly due to challenges distinguishing planned deprescribing from poor adherence. Focusing on individuals with...
Special Collection: Mechanisms of Vasodilatation Endothelium-Dependent Hyperpolarization (MOVD/EDH2024) [0.03%]
专题收编：内皮细胞依赖性血管舒张机制（EDH/MOVD 2024）
Christopher J Garland
Christopher J Garland
Correction to 'Β-LAPachone Ameliorates Doxorubicin-Induced Cardiotoxicity via Regulating Autophagy and Nrf2 Signalling Pathways in Mice' [0.03%]
关于“β- lapachone通过调节自噬和nrf2信号通路改善多柔比星致小鼠心脏毒性的研究”的更正通知
Published Erratum
Basic & clinical pharmacology & toxicology. 2025 Sep;137(3):e70089. DOI:10.1111/bcpt.70089 2025
Assessment of Rivaroxaban Plasma Concentration Using Chromogenic Anti-Xa Assays and UHPLC-MS/MS in Chinese Patients With Atrial Fibrillation [0.03%]
在房颤患者中使用色谱法和UHPLC-MS / MS测定达比加群酯血浆浓度的评估研究
Xiao-Qin Liu,Yi Gu,Yu-Fei Zhang et al.
Xiao-Qin Liu et al.
Accurate quantification of rivaroxaban concentration is essential in some specific clinical situations. A prospective study was conducted to compare the rivaroxaban concentration measured by Zhenyuan anti-Xa assay with that by reference met...
Comparative Study
Basic & clinical pharmacology & toxicology. 2025 Sep;137(3):e70088. DOI:10.1111/bcpt.70088 2025
Xiao-Jie-An Capsule Alleviates Uterine Fibroids by Modulating Oestrogen-Progesterone Balance and Reducing Inflammatory Response [0.03%]
调经消癓胶囊通过调节雌孕激素平衡及降低炎症反应治疗子宫肌瘤
Yi Ying,Jihan Liu,Shanshan Ju et al.
Yi Ying et al.
Uterine fibroids (UF) are benign tumours composed of smooth muscle cells and fibrous connective tissue. UF are common among women aged 30-50 years and often present with symptoms such as anaemia, pelvic pain and bladder dysfunction. Xiao-Ji...
LW-AFC Protects Against Neurological and Neuropsychiatric Effects of SARS-CoV-2 Spike Protein in Mice [0.03%]
LW-AFC保护小鼠免受SARS-CoV-2刺突蛋白引起的神经和神经精神症状
Wenyi Xiao,Jiao Wang,Jianhui Wang et al.
Wenyi Xiao et al.
Numerous clinical studies show that besides respiratory symptoms, COVID-19 patients frequently undergo neurological and neuropsychiatric problems. However, effective treatments for these problems remain insufficient. LW-AFC, derived from tr...
Triterpenoid From Persimmon Leaves (Diospyros kaki L.f.) Exerted Anti-Type 2 Diabetic Effects and No Toxicity in Experimental Animals [0.03%]
柿树叶三萜具有良好的降血糖作用及较低的毒性
Hung Van Nguyen,Ha Thu Thi Nguyen,Nhan Trong Le et al.
Hung Van Nguyen et al.
The acute and subchronic toxicity, along with the anti-type 2 diabetic effects, of a triterpenoid extract from persimmon leaves (Tri DKL) was evaluated in animals. Acute oral toxicity was assessed in Swiss mice, whereas subchronic toxicity ...
The Role of Hydroxychloroquine in the Management of Rheumatic Disorders: A Comprehensive Review [0.03%]
羟氯喹在风湿性疾病管理中的作用：综合回顾
Ilker Ates,Hilal Sahin,Lalu Muhammad Irham et al.
Ilker Ates et al.
A drug preferred for its antimalarial effect called hydroxychloroquine (HCQ) has long been used to manage and avoid malaria. Nevertheless, its exact mode of action is still unknown. HCQ works through a variety of strategies to influence dis...