Diosmin Alleviates Pain via Mechanisms Involving Acetylcholinesterase and TRPV1 Inhibition: An In Silico and In Vivo Study [0.03%]
柚皮素通过乙酰胆碱酯酶和TRPV1抑制机制缓解疼痛：一项基于计算机与动物的研究
Aya Y Al-Kabariti,Belal O Al-Najjar,Mohammad Alsalem et al.
Aya Y Al-Kabariti et al.
Background: Diosmin, a flavonoid glycoside with reported anti-inflammatory effects, was evaluated for its potential analgesic activity using in vivo and in silico studies. ...
Antiseizure Effects of Cannabidiol in Combination With Cannabigerol in the Maximal Electroshock Seizure Model [0.03%]
大电休克模型中抗癫痫药物大麻二酚与胡桃叶绿素的协同作用研究
Han Zhong Zhou,Brian Wayne Scott,Yagoda Izabela Oleksak et al.
Han Zhong Zhou et al.
Current antiseizure therapy for epilepsy is only effective in about 70% of the patient population. Previous studies had shown that the addition of small amounts of tetrahydrocannabinol (THC) made cannabidiol (CBD) much more potent in the ma...
Impact of Reference Accessibility on Drug Information Queries About Medication Manipulation and Intravenous Compatibility [0.03%]
循证医学资料的可获得性对药物信息咨询的影响研究
Jeanie Misko,Matthew D M Rawlins
Jeanie Misko
Evaluation of the Perception of Deprescribing by French Pharmacy Students: A National Observational Study [0.03%]
法国药学专业学生对减药感知的评估：一项全国观察性研究
Jean-François Huon,Baptiste Blanchard,Laurence Spiesser-Robelet et al.
Jean-François Huon et al.
The ageing population, which is often associated with polypharmacy, indicates the need for evolution within the healthcare professions. Future pharmacists must develop new skills and knowledge to meet these challenges, including during thei...
Observational Study
Basic & clinical pharmacology & toxicology. 2026 Feb;138(2):e70196. DOI:10.1111/bcpt.70196 2026
Katrine Bitsch Johansen,Peter Skov Esbech,Johan Fredrik Helland et al.
Katrine Bitsch Johansen et al.
Climate change poses a significant challenge for global health. The World Health Organization estimates 250 000 additional annual deaths between 2030 and 2050 due to global warming. The healthcare sector is a major contributor to greenhouse...
Learnings From a Knowledge Mobilization Strategy to Integrate a Deprescribing Educational Curriculum Into Health Professional Programmes [0.03%]
一项知识传播策略的经验教训：将减药教育课程融入卫生专业项目中
Tiphaine Pierson,Camille Gagnon,Jennifer E Isenor et al.
Tiphaine Pierson et al.
Tramadol-Related Deaths Over a 10-Year Period-An Autopsy Study From Western Denmark [0.03%]
丹麦西部十年 tramadol 相关死亡的尸检研究
Terese Matthesen Kamronn,Asser Hedegaard Thomsen,Sabine Solveig Aftret et al.
Terese Matthesen Kamronn et al.
Due to recently emerging concerns about the nonmedical use of tramadol in Denmark, we hypothesized increasing tramadol detections in medico-legal autopsy cases, with more nonprescribed use and fatal poisonings over time, particularly among ...
Antagonism of Kinin Receptors B1 and B2 Attenuates Folic Acid-Induced Tubulointerstitial Fibrosis in Mice [0.03%]
B1和B2激肽受体拮抗剂可减轻叶酸诱导的小鼠肾小管间质纤维化
Gabriel Rufino Estrela,Alexandre Budu,Juliene Silva et al.
Gabriel Rufino Estrela et al.
Chronic kidney disease (CKD) remains a significant global health burden despite recent advances in pharmacotherapy, including sodium-glucose cotransporter 2 (SGLT2) inhibitors and mineralocorticoid receptor antagonists. Renal fibrosis, a ce...
Sp1-Mettl14 Feedback Loop Promotes Ferroptosis in Mycobacterium tuberculosis-Infected Microglia by Activating Acsl4 [0.03%]
Sp1-Mettl14反馈环通过激活Acsl4促进结核杆菌感染的小胶质细胞铁死亡
Junhao Chu,Quansheng Liu,Xue Chen et al.
Junhao Chu et al.
Central nervous system tuberculosis (CNS-TB) represents a critical form of extrapulmonary tuberculosis, characterized by high mortality and morbidity. The infection of microglia by Mycobacterium tuberculosis (Mtb) is a crucial factor in the...
Fall Risk Awareness and Experiences Among Adult Users of Opioids in Denmark: A Community Pharmacy-Based Questionnaire Pilot Study [0.03%]
丹麦成人阿片类药物使用者的跌倒风险意识和体验：基于社区药房的问卷试点研究
Juliane Maria Rosendahl,Jesper Ryg,Carina Lundby
Juliane Maria Rosendahl