Physical frailty in relation to immunosenescence involving pDC function in the Japanese elderly: a cross-sectional survey study [0.03%]
关于日本老年人与pDC功能相关免疫衰老的体衰：一项横断面调查研究
Yoshihiko Sugihara,Yusuke Ushida,Yuko Fukushima et al.
Yoshihiko Sugihara et al.
Hui Li,Xiaxuan Li,Hangyu Chen et al.
Hui Li et al.
Exercise-induced changes in circulatory aging-related biomarkers among older adults: longitudinal analysis of a multi-stage randomized clinical trial [0.03%]
老年人运动诱导的循环衰老生物标志物变化：多阶段随机临床试验的纵向分析
Qiaowei Li,Tingting Liu,Wei Lin et al.
Qiaowei Li et al.
Aging-associated immune signature as a predictor of mortality in end-stage renal disease: results from the longitudinal iESRD study [0.03%]
纵向iESRD研究结果：年龄相关免疫特征可作为终末期肾病患者死亡率预测因子
Kai-Hsiang Shu,TienYu Owen Yang,Graham Pawelec et al.
Kai-Hsiang Shu et al.
Background: Accelerated immune aging has been implicated in patients with end-stage kidney disease, but a detailed examination of immune profiles correlated with long-term outcomes for these individuals has never been per...
Obese plasma transfer accelerates cellular aging in the C57BL/6 mouse model [0.03%]
肥胖血浆转移可加速C57BL/6小鼠模型的细胞衰老
Shabnam Shahabi Nejad,Hamid Zand,Samira Rastgoo et al.
Shabnam Shahabi Nejad et al.
Background: Obesity induces chronic inflammation and cellular senescence, contributing to metabolic and immune dysfunction. This study investigates the effects of plasma obtained from obese and non-obese C57BL/6 donor mic...
Neutrophil-to-lymphocyte ratio as a sex-specific predictor of short-term mortality in hospitalised older adults with COVID-19: a pragmatic biomarker of inflammaging in acute vulnerability [0.03%]
中性粒细胞与淋巴细胞比率在新冠住院老年患者短期死亡率中的性别特异性预测：急性脆弱性炎症老化生物标志物的实用研究
Chiara Ceolin,Veronica Liberati,Vittorio Acunto et al.
Chiara Ceolin et al.
Background: The neutrophil-to-lymphocyte ratio (NLR) is a low-cost inflammatory biomarker increasingly investigated in older populations as a cross-cutting indicator of immunosenescence and inflammaging. While elevated NL...
Activation of aryl hydrocarbon receptor signaling by indole-3-lactic acid from Bacillus velezensis DS2 reinforces gut mucosal immunity and attenuates inflammaging in aged mice [0.03%]
枯草芽孢杆菌DS2产生的吲哚-3-乳酸通过激活芳香烃受体信号通路增强肠道黏膜免疫并缓解衰老小鼠的炎症老化症状
Xiaofeng Liu,Jipeng Zhou,Qian Hou et al.
Xiaofeng Liu et al.
Background: Aging is characterized by progressive immunosenescence and inflammaging, in which impaired gut barrier and dysregulated mucosal immunity exacerbate systemic senescence. While probiotics modulate gut health, th...
Association of an inflammaging score based on IL-6, IL-10 and CXCL9, and frailty with long-term mortality in hospitalized older adults [0.03%]
基于IL-6、IL-10和CXCL9的炎症老化评分与脆弱性对住院老年人长期死亡率的影响相关性研究
Matilde Sbriscia,Sonia Fantone,Mirko Di Rosa et al.
Matilde Sbriscia et al.
Warmer temperature accelerates senescence by modifying the aging-dependent changes in the mosquito transcriptome, altering immunity, metabolism, and DNA repair [0.03%]
温度升高通过修改蚊子转录组的年龄依赖性变化来加速衰老，从而改变免疫力、代谢和DNA修复能力
Lindsay E Martin,Jordyn S Barr,Jean-Philippe Cartailler et al.
Lindsay E Martin et al.