George Theodorakopoulos,David G Armstrong
George Theodorakopoulos
Biofilms are a key driver of chronicity and treatment failure in diabetic foot ulcers (DFUs), yet clinical evidence quantifying their impact and management remains fragmented. This systematic narrative review synthesised recent evidence (20...
Extracorporeal Shockwave Therapy for Diabetes Related Foot Ulcers: A Pilot Three-Arm Double-Blinded Randomised Controlled Trial [0.03%]
体外冲击波治疗糖尿病足溃疡的三臂双盲随机对照试验试点研究
L Hitchman,R Lathan,B Ravindhran et al.
L Hitchman et al.
There is an urgent need for effective interventions to aid diabetes-related foot ulcer (DFU) healing. This study aimed to test the deliverability of a proposed trial of extracorporeal shockwave therapy (ESWT) for DFU healing. A pilot double...
Randomized Controlled Trial
International wound journal. 2025 Dec;22(12):e70740. DOI:10.1111/iwj.70740 2025
Negative Pressure Wound Therapy Use: Recommendations and Insights From a Middle Eastern Panel of Experts [0.03%]
负压伤口治疗使用：来自中东专家小组的建议和见解
Muneera Ben-Nakhi,Heitham Albeshri,Fahad Aljindan et al.
Muneera Ben-Nakhi et al.
The number of patients requiring wound care is increasing, placing a burden on healthcare institutions and clinicians. While negative pressure wound therapy (NPWT) use has become increasingly common, Middle East-specific wound care guidelin...
An Innovative Dual-Modality Approach Using Laser and Plasma Therapy in the Management of Chronic Diabetic Foot Ulcer With Osteomyelitis: A Case Series [0.03%]
激光与等离子联合治疗慢性糖尿病足溃疡合并骨髓炎的新型双模态疗法：病例系列报告
Fatemeh Harsij Sani,Hadi Harsij Sani
Fatemeh Harsij Sani
Chronic diabetic foot ulcers (DFUs) complicated by osteomyelitis remain a major clinical challenge, often requiring aggressive treatments or surgical intervention. Novel non-invasive approaches such as laser and plasma therapy have shown pr...
Determination of Hemodynamic Response Using fNIRS in Lower Extremity Amputee and Replant Patients [0.03%]
下肢截肢和再植患者的血流动力学反应的fNIRS测定
Esra Süzen,Ömer Özkan,Özlenen Özkan et al.
Esra Süzen et al.
This study investigates cortical reorganisation and hemodynamic responses in individuals with lower extremity amputation and replantation using functional near-infrared spectroscopy (fNIRS). A total of 15 healthy controls, four left lower l...
Ozoile-Stable Ozonides, Derived From Organic Extravirgin Olive Oil, Enhance Wound Healing Process in Patients With Diabetic Chronic Ulcers [0.03%]
源自有机初榨橄榄油的稳定的臭氧化合物可促进糖尿病慢性溃疡患者的伤口愈合过程
Barbara De Angelis,Fabrizio Orlandi,Margarida Fernandes Lopes Morais D&#x;Autilio et al.
Barbara De Angelis et al.
The article describes the outcomes of a single-centre investigation on the use of OZOILE to improve the healing process in patients with chronic diabetic ulcers. This is a non-randomised interventional study which aims to assess the differe...
Effectivity of the Dehydrated Human Amnion/Chorion Membrane Allograft for Diabetic Foot Ulcers in Japan: A Case Series [0.03%]
日本糖尿病足溃疡应用脱水人羊膜/胎盘绒毛膜异体移植的疗效：病例系列研究
Yuta Terabe,Nobuhito Kaneko
Yuta Terabe
EPIFIX, a dehydrated human amnion/chorion membrane allograft, received regulatory approval as a medical device in 2021 by the Ministry of Health, Labour and Welfare following review by the Pharmaceuticals and Medical Devices Agency, for the...
Collagen-ORC Versus Standard Treatment in Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis of Randomised Trials [0.03%]
糖尿病足溃疡胶原蛋白-ORC与常规治疗的系统评价和meta分析
George Theodorakopoulos,David G Armstrong
George Theodorakopoulos
Diabetic foot ulcers (DFUs) are a major cause of infection, hospitalisation, and amputation. Collagen-based dressings-especially collagen combined with oxidised regenerated cellulose (ORC)-are proposed to improve healing by modulating matri...
Testing Sonication and Different Transport Media to Enhance Microbial Detection in Hard-to-Heal Venous Leg Ulcers [0.03%]
检测难治性静脉腿溃疡中微生物的方法及不同运输介质的声波实验研究
Adéla Holubová,Niels A J Cremers,Martin Krause et al.
Adéla Holubová et al.
Hard-to-heal wounds are frequently associated with underlying conditions such as diabetes, vascular disease, and biofilm-related infections. Accurate identification of microbial origin is essential, but is often hindered by biofilms. This s...
Observational Study
International wound journal. 2025 Nov;22(11):e70778. DOI:10.1111/iwj.70778 2025
Application and Efficacy Evaluation of a Modified Ostomy Appliance in Managing Peristomal Irritant Contact Dermatitis: A Randomised Controlled Trial [0.03%]
改良型造口用品防治造口周围刺激性接触性皮炎的应用及疗效评价：随机对照试验
Xiaoxiao Ying,Luqiao Huang,Feng Yu et al.
Xiaoxiao Ying et al.
Irritant contact dermatitis is a common peristomal skin complication. Due to the continuous irritation from intestinal fluids and faeces, the healing of this dermatitis is slow and the condition severely impairs patients' quality of life. T...
Randomized Controlled Trial
International wound journal. 2025 Nov;22(11):e70794. DOI:10.1111/iwj.70794 2025