Transcriptome mining reveals diversity and evolution of circulating and endogenous amphibian retroviruses [0.03%]
转录组测序挖掘揭示了循环和内源两栖动物逆转录病毒的多样性和进化
Emma F Harding,Banjo Webster,Tanu Sridhar et al.
Emma F Harding et al.
Background: The evolutionary history of retroviruses and their impact on vertebrate evolution remains poorly understood, particularly in non-mammalian hosts. In this study, we explore retroviruses associated with Amphibia...
Intra-pol proviral open region of HTLV-1 controls the transcription from both long terminal repeats [0.03%]
人类T细胞白血病病毒Ⅰ型调控区控制双启动子的转录活动
Miyu Sonoda,Azusa Tanaka,Xueda Chen et al.
Miyu Sonoda et al.
Background: Human T-cell leukemia virus type 1 (HTLV-1) infects mainly CD4+ T lymphocytes and causes both malignant and inflammatory diseases: the aggressive malignancy known as Adult T-cell leukemia/lymphoma (ATL) and se...
Unveiling the dynamics: understanding the current scenario and drivers of HIV epidemiology in Pakistan [0.03%]
揭开动态：了解巴基斯坦当前艾滋病流行现状及其驱动因素
Akmal Zubair,Muhammad Ali,Safa Wdidi et al.
Akmal Zubair et al.
Over the past two decades, the global HIV/AIDS pandemic has emerged as one of the most pressing health concerns worldwide. In low-income countries, where resources are scarce, both the prevalence of HIV and the associated mortality rates ha...
Corrado Gurgo,Genoveffa Franchini
Corrado Gurgo
Background: In the early phase of HIV infection, as studied in vitro, high levels of unintegrated (both linear and circular) and integrated (provirus) forms of viral DNA are seen, and cells produce high levels of virus. I...
Correction: HTLV-1 Japanese subgroup in Brazil: phylogenetic and migratory history [0.03%]
巴西的日本人类 T 细胞白血病病毒亚组：系谱和迁徙历史
Carolina Amianti,Larissa Melo Bandeira,Aline Pedroso Lorenz et al.
Carolina Amianti et al.
Published Erratum
Retrovirology. 2025 Jun 4;22(1):10. DOI:10.1186/s12977-025-00666-1 2025
Drug resistance and genetic transmission characteristics of HIV-1 CRF55_01B in people living with HIV/AIDS (PLWHA) in Henan Province, China [0.03%]
河南省艾滋病病毒（HIV）CRF55_01B耐药及遗传特征分析
Jie Ma,Jinjin Liu,Shuguang Wei et al.
Jie Ma et al.
Background: Among the many CRFs, CRF55_01B was the first CRF01_AE and subtype B recombinant strain identified around 2013 among men who have sex with men (MSM) in Shenzhen, China. With rapid spreading throughout the count...
HTLV-1 Japanese subgroup in Brazil: phylogenetic and migratory history [0.03%]
巴西的日本人类T细胞白血病病毒亚群：系谱和迁徙历史
Carolina Amianti,Larissa Melo Bandeira,Aline Pedroso Lorenz et al.
Carolina Amianti et al.
Background: The retrovirus Human T-lymphotropic virus type 1 is classified into different subtypes, and due to its low evolutionary rates, it can be used to explore geographic patterns of origin and dispersion of human po...
Shanshan Wang,Tongtong Du,Jun Yan et al.
Shanshan Wang et al.
Background: Prototype foamy virus (PFV) is a complex retrovirus that can maintain latent infection for life after viral infection of the host. However, the mechanism of latent infection with PFV remains unclear. Our previ...
Therapeutic efficacy of albuvirtide-based antiretroviral therapy in people living with HIV who have low-level viremia and non-AIDS-defining malignancies: two case reports [0.03%]
阿布昔尔tid联合抗逆转录病毒治疗低病毒血症和非艾滋病定义癌的疗效：2例报告
Chuantiao Zhang,Tingting Xie,Yuantao Liu et al.
Chuantiao Zhang et al.
Background: People living with HIV (PLWH) who experience low-level viremia (LLV) face unique challenges in disease management, particularly when diagnosed with concurrent malignancies. Albuvirtide (ABT), a long-acting HIV...
Case Reports
Retrovirology. 2025 Apr 18;22(1):6. DOI:10.1186/s12977-025-00662-5 2025
Aberrant expression of human endogenous retrovirus K9-derived elements is associated with better clinical outcome of acute myelocytic leukemia [0.03%]
人类内源性逆转录病毒K9成分的错误表达与急性骨髓白血病的更好的临床结果相关
Ryo Yanagiya,So Nakagawa,Makoto Onizuka et al.
Ryo Yanagiya et al.
Background: Acute myelocytic leukemia (AML) is a common hematological malignancy in adults. Although several risk stratifications based on cytogenetic and molecular abnormalities are available to guide the indications for...