Impact of exercise on oocyte quality in the POLG mitochondrial DNA mutator mouse [0.03%]
运动对POLG线粒体DNA突变鼠卵母细胞质量的影响
Christine Faraci,Sofia Annis,Joyce Jin et al.
Christine Faraci et al.
The mtDNA 'mutator' mouse, also called the 'POLG' mouse, is a well-characterized model frequently used for studies of progeroid aging. Harboring a mutation in the proofreading domain of the mitochondrial polymerase, polymerase-γ (Polg), PO...
Involvement of fibroblast growth factor 2 (FGF2) and its receptors in the regulation of mouse sperm physiology [0.03%]
成纤维细胞生长因子2（FGF2）及其受体在小鼠精子生理调节中的作用
Lucía Saucedo,Cristian Sobarzo,Nicolás G Brukman et al.
Lucía Saucedo et al.
Fibroblast growth factor 2 (FGF2) and its receptors (FGFRs) have been described in several tissues, where they regulate cellular proliferation, differentiation, motility and apoptosis. Although FGF2/FGFRs expression in the male reproductive...
Progressive methylation of POU5F1 regulatory regions during blastocyst development [0.03%]
囊胚发育过程中POU5F1调控区域的渐进甲基化现象
E Canon,L Jouneau,T Blachère et al.
E Canon et al.
The POU5F1 gene encodes one of the 'core' transcription factors necessary to establish and maintain pluripotency in mammals. Its function depends on its precise level of expression, so its transcription has to be tightly regulated. To date,...
Peri-ovarian adipose tissue contributes to intraovarian control during folliculogenesis in mice [0.03%]
卵周脂肪组织参与小鼠卵泡发生过程中的卵巢内控制作用
Liuhong Yang,Lei Chen,Xiaosheng Lu et al.
Liuhong Yang et al.
Peri-ovarian adipose tissue (POAT) is a kind of intra-abdominal white adipose tissue that is present surrounding the ovaries in rodents. Recent studies demonstrated that POAT-deficient mice displayed a phenotype of delayed antral follicular...
Effects of micronutrients on placental function: evidence from clinical studies to animal models [0.03%]
微量营养素对胎盘功能影响的临床与动物研究证据
Bernadette C Baker,Dexter Jl Hayes,Rebecca L Jones
Bernadette C Baker
Micronutrient deficiencies are common in pregnant women due to low dietary intake and increased requirements for fetal development. Low maternal micronutrient status is associated with a range of pregnancy pathologies involving placental dy...
Reproductive performance of male mice after hypothalamic ghrelin administration [0.03%]
脑室内给予胃激素对雄性小鼠生殖行为的影响
María Belén Poretti,Camila Frautschi,Eugenia Luque et al.
María Belén Poretti et al.
It has been demonstrated that food intake and reproductive physiology are both simultaneously modulated to optimize reproductive success under fluctuating metabolic conditions. Ghrelin (GHRL) is an orexigenic peptide identified as the endog...
Adam J Ziecik,Emilia Przygrodzka,Beenu M Jalali et al.
Adam J Ziecik et al.
The new corpora lutea (CLs) in pigs are formed from the preovulatory follicles after the luteinizing hormone (LH) surge. However, total autonomy and independence of CLs from LH up to Day 12 of cycle has recently been questioned. Transformat...
Ovine prenatal growth restriction impacts glucose metabolism and body composition throughout life in both sexes [0.03%]
卵生前生长限制影响终生两性葡萄糖代谢和身体组成
Jacqueline M Wallace,John S Milne,Raymond P Aitken et al.
Jacqueline M Wallace et al.
Low birthweight is a risk factor for later adverse health. Here the impact of placentally mediated prenatal growth restriction followed by postnatal nutrient abundance on growth, glucose metabolism and body composition was assessed in both ...
Metformin counteracts the effects of FSH on rat Sertoli cell proliferation [0.03%]
二甲双胍可抵抗FSH对大鼠支持细胞增殖的影响
Gustavo Marcelo Rindone,Agostina Gorga,Mariana Regueira et al.
Gustavo Marcelo Rindone et al.
Metformin (MET) is one of the most widely used anti-hyperglycemic agents for treating patients with type 2 diabetes and it has started to be used in pediatric population at ages when Sertoli cells are still proliferating. It is well known t...
Objective evaluation of ram and buck sperm motility by using a novel sperm tracker software [0.03%]
利用新型精子跟踪软件客观评价公羊和公鹿的精子活动力
F Buchelly Imbachí,L Zalazar,J I Pastore et al.
F Buchelly Imbachí et al.
This work offers researchers the first version of an open-source sperm tracker software (Sperm Motility Tracker, V1.0) containing a novel suit of algorithms to analyze sperm motility using ram and buck sperm as models. The computer-assisted...