In vitro development of ovine follicles from the preantral to antral stages depends on initial follicle diameter and promotes oocyte growth and transzonal projections formation [0.03%]
卵泡体外培养依赖于初始直径决定了羊卵母细胞的生长和跨区丝形成
Feriel Yasmine Mahiddine,Gaëlle Lefort,Renaud Fleurot et al.
Feriel Yasmine Mahiddine et al.
Ovine follicle culture recapitulates several features of the preantral-to-antral transition, including morphological changes and granulosa cells proliferation and differentiation. Although the influence of initial follicle diameter on in vi...
Sorting nexin 9 (SNX9) dysregulation impairs decidualization and correlates with severe preeclampsia [0.03%]
SNX9表达失调与重度子痫前期的发生密切相关
Kaixuan Wang,Rui Fu,Yanxin Xu et al.
Kaixuan Wang et al.
Preeclampsia (PE) is a gestational hypertension disorder emerging after 20 weeks of pregnancy, complicating 5-8% of pregnancies and representing a leading cause of maternal-fetal morbidity and mortality. Despite its clinical significance, t...
Dual Regulation of NK Cells by the Decidualization Milieu: Stromal Cell-Independent and Stromal Cell-Dependent Mechanisms [0.03%]
蜕膜微环境对NK细胞的双重调控作用：脱离基质细胞独立机制和依赖基质细胞机制
Negar Vanaki,Banafsheh Tavangar,Maryam Darzi et al.
Negar Vanaki et al.
Decidualization of endometrial stromal cells (EnSCs) is essential for implantation in part by modulating endometrial immune network. Although menstrual blood-derived stromal cells (MenSCs) are considered as EnSC surrogate, little is known a...
Species-specific differences in cumulus support during final oocyte maturation in mice and cattle [0.03%]
小鼠和奶牛在最终卵母细胞成熟的胞浆颗粒细胞支持上的差异性
Taisiia Yurchuk,Pawel Likszo,Karolina Lukasik et al.
Taisiia Yurchuk et al.
Cumulus-oocyte communication is a key regulator of oocyte maturation; however, comparative studies across species relevant to the choice of models for human in vitro maturation (IVM) remain insufficient. We compared bovine and murine germin...
AI-derived oocyte morphology and follicular fluid biomarkers in donors [0.03%]
捐卵者衍生的卵母细胞形态和卵泡液生物标志物的人工智能研究
Yamila Herrero,Candela Velázquez,Melanie Neira et al.
Yamila Herrero et al.
Oocyte quality is a key determinant of reproductive success, yet its assessment in assisted reproduction largely relies on subjective morphological criteria. Artificial intelligence (AI)-based image analysis has introduced greater objectivi...
Species-Specific Mechanisms of Sperm Transport: Predominant Roles of Motility in Ewes and Uterine Contractility in Mares [0.03%]
物种特异性精子运输机制：母羊以精子motility为主及母马以子宫收缩力为主
Elie Barakat,Erika Caldas,Fabrice Reigner et al.
Elie Barakat et al.
The factors controlling sperm transport within the female genital tract vary among species. The aim of this study was to quantify the respective roles of sperm motility and uterine contractions in passage of sperm within the reproductive tr...
Pregnanolone appearance coincides with the period of implantation following embryonic diapause in the roe deer [0.03%]
胚胎蛰伏后的着床期出现孕烷酮
Sara Elsafadi,Haolin Chen,Reto Giacometti et al.
Sara Elsafadi et al.
Roe deer (Capreolus capreolus) are seasonal animals with fertilisation taking place in summer (July/August). Thereafter, the embryo enters a 4-5-month period of embryonic diapause. This reproductive strategy, displaying a reduced embryonic ...
SMCP Maintains ROS Homeostasis During Sperm Mitochondrial Sheath Assembly [0.03%]
SMCP在精子线粒体鞘组装过程中维持ROS稳态
Chang Wang,Xun Xia,Yudie Guo et al.
Chang Wang et al.
Abnormal morphology or function of the sperm mitochondrial sheath is a major cause of asthenozoospermia, yet the mechanisms governing its assembly and functional maturation remain poorly understood. SMCP is a mitochondrial sheath-associated...
Unveiling the formation of the primordial follicle pool in goats: Insights from single-cell omics analysis [0.03%]
单细胞组学分析揭示山羊始原卵泡库的形成机制
Yong Ruan,Dongwei An,Lingang Dai et al.
Yong Ruan et al.
Mammalian primordial follicles, essential for female reproduction, form a finite nonrenewable pool perinatally, with species-specific developmental variations. This study employed single-cell RNA sequencing (scRNA-seq) to map the transcript...
SP1 controls zygotic genome activation and morula-to-blastocyst transition in mouse embryos [0.03%]
SP1控制小鼠胚胎基因组激活及卵裂球向囊胚的转变
Ai Di,Huang Rong,Wang Fang et al.
Ai Di et al.
Specificity protein 1 (SP1) is the most active member of the specificity protein and Krüppel-like factor (Sp/KLF) family and is widely expressed across all mammalian cell types. However, more detailed studies on the role of SP1 in preimpla...