Identification of potential MicroRNA Markers in Plasma Vesicles for Giant Panda Pregnancy Diagnosis [0.03%]
用于鉴别大熊猫怀孕的潜在标志物MicroRNA的识别研究
Meiling Cheng,Yingmin Zhou,Bo Luo et al.
Meiling Cheng et al.
Extracellular vesicle microRNAs play direct and indirect roles in pregnancy across humans and animal models, making them potential biomarkers for pregnancy detection. Here, a total of 15 blood samples were collected to profile extracellular...
Thigmotactic navigation and functional enrichment of boar sperm in microfluidic channels [0.03%]
微流体通道中公猪精子的触机导航及其功能增益
Mehran Dabiri,Tara Lea Bampton,Roslyn Bathgate et al.
Mehran Dabiri et al.
Efficient sperm selection is crucial for reproductive success in pigs, where artificial insemination (AI) is the main method of assisted reproduction. Traditional methods such as density gradient centrifugation (DGC) can enrich motile sperm...
Functional Identification of miR-21-5p from Fallopian Tubal Extracellular Vesicles as a Promoter of Preimplantation Embryo Viability [0.03%]
来自输卵管细胞外囊泡的miR-21-5p能够促进胚胎植入前存活的功能性鉴定
Yuehan Li,Mingwei Lv,Wenjing Xiong et al.
Yuehan Li et al.
Extracellular vesicles (EVs) released by the maternal reproductive tract provide essential biochemical support for early embryo development, yet the identity of their functional molecular cargo remains largely unclear. In this study, we iso...
The Role of Heterogeneous Nuclear Ribonucleoproteins in Mammalian Spermatogenesis: Mechanisms and Clinical Implications [0.03%]
不均一核核糖核蛋白在哺乳动物精子发生中的作用：机制及临床意义
Kaili Zhou,Kejin Ren,Yijia An et al.
Kaili Zhou et al.
Spermatogenesis in mammals is a complex and highly orchestrated process of cellular development that necessitates precise regulation at the transcriptional, post-transcriptional, and translational levels. RNA binding proteins (RBPs) are int...
Protective Effects of Metformin and Vitamin C on Diabetes-Induced Testicular Dysfunction [0.03%]
二甲双胍和维生素C对糖尿病诱导的睾丸功能障碍的保护作用
Süheyla Esra Özkoçer,Gamze Guney Eskiler,Ece Konac
Süheyla Esra Özkoçer
This study aimed to investigate the potential protective effects of combined metformin (Met) and vitamin C (VitC) therapy on diabetes mellitus (DM)-induced testicular damage, sperm parameters, and the regulation of gene and protein expressi...
AMH drives chicken ovarian germline stem cell proliferation through the canonical Smad pathway in the avian ovary [0.03%]
AMH通过经典的Smad途径在鸟类卵巢中驱动鸡卵母细胞干细胞增殖
Qing Sun,Changhao Yu,Hongcai Sun et al.
Qing Sun et al.
The OSCs population in postnatal chickens is a potential reservoir for follicular renewal, however, the signals that regulate OSC maintenance and expansion are not well understood. Here, we identify anti-Müllerian hormone (AMH) as a key mi...
Evidence for a novel role of Pregnancy-Associated Glycoproteins in maintenance of the bovine CL of pregnancy [0.03%]
妊娠相关糖蛋白在维持牛妊娠黄体功能中的新作用证据
Livia Martino-Duarte,João Paulo N Andrade,Pedro L J Monteiro et al.
Livia Martino-Duarte et al.
Embryonic interferon-tau (IFNT) suppresses oxytocin-induced endometrial prostaglandin F2a (PGF) pulses, likely involved in maintaining the bovine CL during early pregnancy. After Day 21 of bovine pregnancy, oxytocin-induced PGF pulses are o...
Ovarian responses to 17ɑ-ethinylestradiol in a marine livebearer, the Southern crested weedfish [0.03%]
17α-乙炔基雌二醇对鱼类卵巢的影响以南拟无须刺胎鱼为模式生物的研究
Rhiannon V Eastment,Shiho Ozeki,Jack L Manera et al.
Rhiannon V Eastment et al.
Pharmaceuticals are fast becoming a major source of environmental pollution. Many pharmaceuticals are endocrine disruptors and can thus interfere with the endocrine system of exposed organisms, leading to a suite of behavioural and physiolo...
Essential role of METTL3 in mitochondrial function and epigenetic regulation during preimplantation development in mice [0.03%]
METTL3在小鼠胚胎着床前发育中的线粒体功能和表观遗传调控中发挥重要作用
Dan Liu,Xinyao Chen,Yuwei Gao et al.
Dan Liu et al.
Methyltransferase-like 3 (METTL3) is a key enzyme involved in N6-methyladenosine (m6A) RNA modification. METTL3 affects mitochondrial function via its well-known contribution to RNA translation and stability. Since METTL3 is essential for p...
Uterine fluid EV miR-223-3p as endometrial receptivity biomarker and regulator in implantation [0.03%]
子宫液中的EV miR-223-3p 是植入窗的标志物和调控因子
Xi Huang,Aihua He,Runxin Gan et al.
Xi Huang et al.
Endometrial receptivity (ER) is a pivotal determinant of successful embryo implantation, yet its regulation by uterine fluid (UF) extracellular vesicles (EVs) remains poorly understood. This study aimed to identify key UF EV miRNAs during t...