AI-derived oocyte morphology and follicular fluid biomarkers in donors [0.03%]
捐卵者衍生的卵母细胞形态和卵泡液生物标志物的人工智能研究
Yamila Herrero,Candela Velázquez,Melanie Neira et al.
Yamila Herrero et al.
Oocyte quality is a key determinant of reproductive success, yet its assessment in assisted reproduction largely relies on subjective morphological criteria. Artificial intelligence (AI)-based image analysis has introduced greater objectivi...
Species-Specific Mechanisms of Sperm Transport: Predominant Roles of Motility in Ewes and Uterine Contractility in Mares [0.03%]
物种特异性精子运输机制：母羊以精子motility为主及母马以子宫收缩力为主
Elie Barakat,Erika Caldas,Fabrice Reigner et al.
Elie Barakat et al.
The factors controlling sperm transport within the female genital tract vary among species. The aim of this study was to quantify the respective roles of sperm motility and uterine contractions in passage of sperm within the reproductive tr...
Pregnanolone appearance coincides with the period of implantation following embryonic diapause in the roe deer [0.03%]
胚胎蛰伏后的着床期出现孕烷酮
Sara Elsafadi,Haolin Chen,Reto Giacometti et al.
Sara Elsafadi et al.
Roe deer (Capreolus capreolus) are seasonal animals with fertilisation taking place in summer (July/August). Thereafter, the embryo enters a 4-5-month period of embryonic diapause. This reproductive strategy, displaying a reduced embryonic ...
SMCP Maintains ROS Homeostasis During Sperm Mitochondrial Sheath Assembly [0.03%]
SMCP在精子线粒体鞘组装过程中维持ROS稳态
Chang Wang,Xun Xia,Yudie Guo et al.
Chang Wang et al.
Abnormal morphology or function of the sperm mitochondrial sheath is a major cause of asthenozoospermia, yet the mechanisms governing its assembly and functional maturation remain poorly understood. SMCP is a mitochondrial sheath-associated...
Unveiling the formation of the primordial follicle pool in goats: Insights from single-cell omics analysis [0.03%]
单细胞组学分析揭示山羊始原卵泡库的形成机制
Yong Ruan,Dongwei An,Lingang Dai et al.
Yong Ruan et al.
Mammalian primordial follicles, essential for female reproduction, form a finite nonrenewable pool perinatally, with species-specific developmental variations. This study employed single-cell RNA sequencing (scRNA-seq) to map the transcript...
SP1 controls zygotic genome activation and morula-to-blastocyst transition in mouse embryos [0.03%]
SP1控制小鼠胚胎基因组激活及卵裂球向囊胚的转变
Ai Di,Huang Rong,Wang Fang et al.
Ai Di et al.
Specificity protein 1 (SP1) is the most active member of the specificity protein and Krüppel-like factor (Sp/KLF) family and is widely expressed across all mammalian cell types. However, more detailed studies on the role of SP1 in preimpla...
Transcriptomic profiling of exRNA from spent human embryonic-cleavage culture medium reveals potential in embryo quality assessment：a retrospective study [0.03%]
人胚胎卵裂期培养上清外泌体高通量测序筛选胚胎质量评估新标志物：一项回顾性研究
Yuxian Feng,Min Pan,Kai Deng et al.
Yuxian Feng et al.
The exRNA transcriptome of the preimplantation embryo culture medium constitutes a comprehensive profile of embryonic RNAs, offering a non-invasive resource for elucidating developmental status. To delineate its relationship with the matern...
Chorioamnionitis and Glucocorticoids Elicit Acute Adverse Effects on the Developing Ovine Fetal Ovaries [0.03%]
胎盘炎和糖皮质激素急性的不良影响导致卵母细胞发育受损和早期颗粒-膜细胞通讯中断：一只羊的体外研究
K Y M Seah,S W D Carter,H Usuda et al.
K Y M Seah et al.
Antenatal corticosteroid (ANS) therapy and chorioamnionitis are common antecedents of preterm birth, yet their effects on the developing fetal ovary remain poorly understood. Long-term follow-up of 45% of participants from the Auckland Ster...
Anita Bichisecchi,Petra Mikec,Christopher Thomas
Anita Bichisecchi
Ovulation is the process by which an egg is released from an ovarian follicle, ready for fertilisation. It is a multi-scale transformation that converts endocrine cues into coordinated tissue and extracellular matrix remodelling, culminatin...