Transposons and the PIWI pathway: genome defense in gametes and embryos [0.03%]
转座子和PIWI信号通路：生殖细胞和胚胎中的基因组防卫
Stewart J Russell,Jonathan LaMarre
Stewart J Russell
Hiding in plain sight within the genome of virtually every eukaryotic organism are large numbers of sequences known as transposable elements (TEs). These sequences often comprise 50% or more of the DNA in many mammals and are transcriptiona...
Transposons and the PIWI pathway: genome defense in gametes and embryos [0.03%]
转座子和PIWI途径：生殖细胞和胚胎的基因组防御机制
Stewart J Russell,Jonathan LaMarre
Stewart J Russell
Hiding in plain sight within the genome of virtually every eukaryotic organism are large numbers of sequences known as transposable elements (TEs). These sequences often comprise 50% or more of the DNA in many mammals and are transcriptiona...
Osmotic stress induces JNK-dependent embryo invasion in a model of implantation [0.03%]
渗透压力通过JNK诱导模型着床中的胚胎侵袭现象
Peter T Ruane,Rebekka Koeck,Stéphane C Berneau et al.
Peter T Ruane et al.
In vitro culture during assisted reproduction technologies (ART) exposes pre-implantation embryos to environmental stressors, such as non-physiological nutritional, oxidative and osmotic conditions. The effects on subsequent implantation ar...
Piotr Kaczynski,Monika Baryla,Ewelina Goryszewska et al.
Piotr Kaczynski et al.
Successful establishment and development of pregnancy requires proper communication between developing conceptuses and the maternal reproductive tract. Prostaglandins are key players involved in the regulation of reproductive processes in m...
Indoleamine 2,3-dioxygenase suppresses the cytotoxicity of 1 NK cells in response to ectopic endometrial stromal cells in endometriosis [0.03%]
吲哚胺2,3-双加氧酶通过响应子宫内膜异位症中异位子宫内膜成纤维细胞的刺激而抑制自然杀伤细胞的细胞毒性作用
Xuan-Tong Liu,Hui-Ting Sun,Zhong-Fang Zhang et al.
Xuan-Tong Liu et al.
It has been reported that the impaired cytotoxicity of natural killer (NK) cells and abnormal cytokines that are changed by the interaction between ectopic endometrial cells and immune cells is indispensable for the initiation and developme...
Luteal ANGPT-TIE system during selected stages of pregnancy, and normal and antigestagen-induced luteolysis in the dog [0.03%]
犬选择性妊娠阶段及正常和抗孕激素诱导黄体退化期间的黄体ANGPT-TIE系统
Aykut Gram,Miguel Tavares Pereira,Alois Boos et al.
Aykut Gram et al.
Rapid establishment of a vascular network is essential for normal functionality of the corpus luteum (CL). The early luteal phase is associated with increased expression of the VEGF system in canine CL. Acting in synchrony with angiopoietin...
Jorge Cerbón,Noemi Baranda-Avila,Alejandro Falcón-Muñoz et al.
Jorge Cerbón et al.
Sphingolipids are involved in the regulation of cell proliferation. It has been reported that diacylglycerol and sphingosine-1-phosphate generation, during the synthesis of phospho-sphingolipids, is necessary for both, G1-S transition of ce...
C Passaro,D Tutt,D J Mathew et al.
C Passaro et al.
The objectives of this study were (i) to determine whether blastocyst-induced responses in endometrial explants were detectable after 6- or 24-h co-culture in vitro; (ii) to test if direct contact is required between embryos and the endomet...
IRF5 is increased in labouring myometrium and regulates pro-labour mediators [0.03%]
IRF5在临产子宫平滑肌中增加并调控促启动因子
Ratana Lim,Gillian Barker,Martha Lappas
Ratana Lim
Preterm birth continues to be the leading cause of neonatal mortality and morbidities that can extend into adult life. Few treatment options stem from our incomplete understanding of the mechanisms of human labour and delivery. Activation o...
The 40th anniversary of human IVF: time to celebrate and time to reflect [0.03%]
人类体外受精技术诞生四十周年：值得庆祝和反思的时候到了
R M L Winston
R M L Winston