A functional role for AMPK in female fertility and endometrial regeneration [0.03%]
AMPK在女性生育和子宫内膜再生中的功能作用
Melissa L McCallum,Cindy A Pru,Andrea R Smith et al.
Melissa L McCallum et al.
Adenosine monophosphate-activated protein kinase (AMPK) is a highly conserved heterotrimeric complex that acts as an intracellular energy sensor. Based on recent observations of AMPK expression in all structures of the female reproductive s...
SPAM1 and PH-20 are two gene products expressed in bovine testis and present in sperm [0.03%]
牛睾丸中的SPAM1和PH-20两种基因产物在精子中存在
Andrée-Anne Saindon,Pierre Leclerc
Andrée-Anne Saindon
Sperm adhesion molecule 1 (SPAM1) is a sperm protein possessing a hyaluronidase domain in its N-terminus and a zona pellucida-binding domain in its C-terminus. Our previous studies showed that bovine spermatozoa potentially have 2 SPAM1 iso...
Proteomic changes in uterine flushings after levonorgestrel treatment and effects on sperm function [0.03%]
利伏诺节孕素对子宫冲洗物蛋白质组变化的影响及对精子功能的作用
Gabriela Hernández-Silva,Marta Durand,Fernando Larrea et al.
Gabriela Hernández-Silva et al.
When levonorgestrel (LNG) is given for emergency contraception during the follicular phase, it not only inhibits or delays ovulation, but also induces changes in endometrial secretions that modulate sperm functionality. In order to characte...
Siennah R Miller,Nathan J Cherrington
Siennah R Miller
The blood-testis barrier protects developing germ cells by limiting the entry of xenobiotics into the adluminal compartment. There is strong evidence that the male genital tract can serve as a sanctuary site, an area of the body where tumor...
Chronic estradiol exposure - harmful effects on behavior, cardiovascular and reproductive functions [0.03%]
慢性雌二醇暴露对行为、心血管和生殖功能的有害影响
Sheba M J MohanKumar,Priya Balasubramanian,Madhan Subramanian et al.
Sheba M J MohanKumar et al.
Estradiol (E2) is a female hormone that is produced largely by the ovaries, but also by the adrenal glands, fat and liver. It is present in the circulation of both males and females. Many studies in the literature have described how E2 is b...
MiRNA-335-5p negatively regulates granulosa cell proliferation via SGK3 in PCOS [0.03%]
microRNA-335-5p通过SGK3负向调节PCOS颗粒细胞增殖
Lihua Yao,Mingyang Li,Jingwen Hu et al.
Lihua Yao et al.
Polycystic ovary syndrome (PCOS) is a major cause of infertility in women of reproductive age. However, its exact etiology remains unknown. In this study, we sequenced miRNAs in human follicular fluid and identified 16 downregulated and 3 u...
Retinoid signaling controlled by SRC-2 in decidualization revealed by transcriptomics [0.03%]
SRC-2调控的蜕膜化过程中视黄醇信号转导的转录组学研究
Maria M Szwarc,Lan Hai,William E Gibbons et al.
Maria M Szwarc et al.
Establishment of a successful pregnancy requires not only implantation of a healthy embryo into a receptive uterus but also progesterone receptor (PGR)-dependent transformation of endometrial stromal cells (ESCs) into specialized decidual c...
Retinoid signaling controlled by SRC-2 in decidualization revealed by transcriptomics [0.03%]
SRC-2调控的蜕膜化过程中视黄醇信号转导的转录组分析
Maria M Szwarc,Lan Hai,William E Gibbons et al.
Maria M Szwarc et al.
Establishment of a successful pregnancy requires not only implantation of a healthy embryo into a receptive uterus but also progesterone receptor (PGR)-dependent transformation of endometrial stromal cells (ESCs) into specialized decidual c...
Androgens in maternal vascular and placental function: implications for preeclampsia pathogenesis [0.03%]
雄激素在母体血管和胎盘功能中的作用：对子痫前期发病机制的影响
Sathish Kumar,Geoffrey H Gordon,David H Abbott et al.
Sathish Kumar et al.
Adequate maternal vascular adaptations and blood supply to the uterus and placenta are crucial for optimal oxygen and nutrient transport to growing fetuses of eutherian mammals, including humans. Multiple factors contribute to hemodynamics ...
Human pluripotent stem cells in regenerative medicine: where do we stand? [0.03%]
人类多能干细胞在再生医学中的应用及其进展
Ha Thi Nguyen,Kurt Jacobs,Claudia Spits
Ha Thi Nguyen
Human pluripotent stem cells have the capacity to self-renew indefinitely and the ability to differentiate into all cell types of a human body. These characteristics instill them with an enormous promise in regenerative medicine, where they...