Cytotoxic effects of Shiga toxin-2 on human extravillous trophoblast cell lines [0.03%]
Shiga毒素2对人绒毛外滋养细胞系的细胞毒性作用
María Luján Scalise,María Marta Amaral,Julieta Reppetti et al.
María Luján Scalise et al.
Shiga toxin (Stx2) producing Escherichia coli infections during early gestation may impair placentation through a Stx2 damage of extravillous trophoblast (EVT) cells. We have previously demonstrated that Stx2 injected in rats in the early s...
Cervical mucus sialic acid content determines the ability of frozen-thawed ram sperm to migrate through the cervix [0.03%]
宫颈粘液中神经氨酸的含量决定了冻融公羊精子穿越子宫颈的能力
L Richardson,J P Hanrahan,T Tharmalingam et al.
L Richardson et al.
The aim of this study was to investigate the properties and to functionally characterize the cervical mucus that modulates sperm transport through the cervix by using ewe breeds with a divergent pregnancy rate (Belclare and Suffolk; high an...
Emerging role for SRC family kinases in junction dynamics during spermatogenesis [0.03%]
SRC家族激酶在精子发生过程中粘附连接动态变化中扮演的新角色
Xiang Xiao,Yue Yang,Baiping Mao et al.
Xiang Xiao et al.
SRC family kinases (SFKs) are known regulators of multiple cellular events, including cell movement, differentiation, proliferation, survival and apoptosis. SFKs are expressed virtually by all mammalian cells. They are non-receptor protein ...
Trophoblast-derived hyaluronan promotes the regulatory phenotype of decidual macrophages [0.03%]
滋养层来源的透明质酸促进蜕膜巨噬细胞向调节表型分化
Songcun Wang,Fengrun Sun,Mutian Han et al.
Songcun Wang et al.
There is delicate crosstalk between fetus-derived trophoblasts (Tros) and maternal cells during normal pregnancy. Dysfunctions in interaction are highly linked to some pregnancy complications, such as recurrent spontaneous abortion (RSA), p...
In vitro and in vivo mouse follicle development in ovaries and reaggregated ovaries [0.03%]
体外和体内小鼠卵泡发育评估及重组卵巢移植研究
Belinda K M Lo,Sairah Sheikh,Suzannah A Williams
Belinda K M Lo
Follicle development requires complex and coordinated interactions between both the oocyte and its associated somatic cells. In ovarian dysfunction, follicle development may be abnormal due to defective somatic cell function; for example, p...
Acute restraint stress triggers progesterone withdrawal and endometrial breakdown and shedding through corticosterone stimulation in mouse menstrual-like model [0.03%]
急性限制性压力通过皮质酮刺激触发孕酮撤退和类月经小鼠子宫内膜脱落
Shu-Fang Wang,Xi-Hua Chen,Bin He et al.
Shu-Fang Wang et al.
Stress impacts the reproductive axis at the level of the hypothalamus and the pituitary gland, which exert an effect on the ovary. Menstruation is regulated by the hypothalamic-pituitary-ovary (HPO) axis. However, the role of stress in mens...
Stearoyl-coenzyme A desaturase 1 is required for lipid droplet formation in pig embryo [0.03%]
硬脂酰辅酶A脱氢酶1对猪胚胎脂滴形成是必需的
Dong-Kyung Lee,Kwang-Hwan Choi,Jae Yeon Hwang et al.
Dong-Kyung Lee et al.
Lipid droplets (LD) provide a source of energy, and their importance during embryogenesis has been increasingly recognized. In particular, pig embryos have larger amounts of intercellular lipid bilayers than other mammalian species, suggest...
Blastocysts exhibit sex-specific signalling of IFNT transcription, translation and activity [0.03%]
雌雄胚胎囊胚期IFNT的转录、翻译及活性的性别特异性差异表达研究
Corina I Schanzenbach,Sandra M Bernal-Ulloa,Vera A van der Weijden et al.
Corina I Schanzenbach et al.
Preimplantation bovine blastocyst supernatants exhibit sex-dependent antiviral activity, due to the ruminant pregnancy recognition signal interferon tau (IFNT). Differing potencies of IFNT variants have been supposed as cause, although evid...
Jessica E M Dunleavy,Moira K O&#x;Bryan,Peter G Stanton et al.
Jessica E M Dunleavy et al.
As germ cells progress through spermatogenesis, they undergo a dramatic transformation, wherein a single, diploid spermatogonial stem cell ultimately produces thousands of highly specialised, haploid spermatozoa. The cytoskeleton is an inte...
MED20 is essential for early embryogenesis and regulates NANOG expression [0.03%]
MED20对于早期胚胎发育是必需的，并调控NANOG表达
Wei Cui,Chelsea Marcho,Yongsheng Wang et al.
Wei Cui et al.
Mediator is an evolutionarily conserved multi-subunit complex, bridging transcriptional activators and repressors to the general RNA polymerase II (Pol II) initiation machinery. Though the Mediator complex is crucial for the transcription o...