WOMEN IN REPRODUCTIVE SCIENCE: Discovering science and the ovary: a career of joy [0.03%]
生殖科学中的女性研究人员：探索科学与卵巢：快乐的事业
JoAnne S Richards
JoAnne S Richards
My career has been about discovering science and learning the joys of the discovery process itself. It has been a challenging but rewarding process filled with many exciting moments and wonderful colleagues and students. Although I went to ...
Natalie A Trigg,Andrew L Eamens,Brett Nixon
Natalie A Trigg
It is now well established that mature spermatozoa harbour a rich and diverse profile of small non-protein-coding regulatory RNAs (sRNAs). There is also growing appreciation that this sRNA profile displays considerable plasticity, being alt...
H19 regulates trophoblastic spheroid adhesion by competitively binding to let-7 [0.03%]
H19通过竞争性结合LET-7调控滋养层细胞球粘附作用
Dongmei He,Hong Zeng,Jingfei Chen et al.
Dongmei He et al.
Integrin β3 (ITGB3), which is the target gene of the miRNA let-7 that can be antagonized by long noncoding RNA (lncRNA) H19, is well known to have a critical role in endometrium receptivity. However, the regulation of ITGB3 in cell-cell or...
Progesterone alters the bovine uterine fluid lipidome during the period of elongation [0.03%]
孕酮改变了牛子宫上皮腔液在胚胎延展期的脂质组分
Constantine A Simintiras,José M Sánchez,Michael McDonald et al.
Constantine A Simintiras et al.
Successful bovine pregnancy establishment hinges on conceptus elongation, a key reproductive phenomenon coinciding with the period during which most pregnancies fail. Elongation is yet to be recapitulated in vitro, whereas in vivo it is dir...
Cyclin-dependent kinase 21 is a novel regulator of proliferation and meiosis in the male germline of zebrafish [0.03%]
周期素依赖性激酶21是斑马鱼雄性生殖细胞增殖和减数分裂的新调节因子
Kaitlyn A Webster,Katrin Henke,Delaney M Ingalls et al.
Kaitlyn A Webster et al.
Germ cell differentiation and maintenance relies on complex regulation of mitotic and meiotic progression. Cyclin-dependent kinases (CDKs) and their activating cyclin partners are known to have specialized roles in regulating cell cycle pro...
Serum and tissue pregnanes and pregnenes after dexamethasone treatment of cows in late gestation [0.03%]
妊娠后期给予地塞米松后母牛血液和组织中的孕烷和甲基孕烷类固醇动态变化
Alan J Conley,Erin L Legacki,C Jo Corbin et al.
Alan J Conley et al.
Dexamethasone (DEX) initiates parturition by inducing progesterone withdrawal and affecting placental steroidogenesis, but the effects of DEX in fetal and maternal tissue steroid synthetic capacity remains poorly investigated. Blood was col...
New insights of the role of β-NGF in the ovulation mechanism of induced ovulating species [0.03%]
β-NGF在诱导排卵物种中作用的新见解
Marcelo H Ratto,Marco Berland,Mauricio E Silva et al.
Marcelo H Ratto et al.
The type of stimuli triggering GnRH secretion has been used to classify mammalian species into two categories: spontaneous or induced ovulators. In the former, ovarian steroids produced by a mature follicle elicit the release of GnRH from t...
Notch activity mediates oestrogen-induced stromal cell invasion in endometriosis [0.03%]
notch活性介导了内异症间质细胞侵袭作用的雌激素反应性
Na Li,Ling Zhang,Qi Li et al.
Na Li et al.
Oestrogen has been reported to control the invasiveness of endometrial stromal cells in endometriosis. Notch signalling, a master regulator of cell invasion in tumours, is regulated by oestrogen in other diseases and hyperactivated in endom...
DZNep and UNC0642 enhance in vitro developmental competence of cloned pig embryos [0.03%]
DZNep和UNC0642能够提高克隆猪胚胎的发育潜能
Chengfa Zhao,Junsong Shi,Rong Zhou et al.
Chengfa Zhao et al.
Somatic cell nuclear transfer in mammalian cloning suffers from a faulty epigenetic reprogramming, which is believed to cause developmental failures in cloned embryos. Regulating the epigenetic-modifying enzymes can rescue the chromatin of ...
Update on mammalian sperm capacitation: how much does the horse differ from other species? [0.03%]
哺乳动物精子获能的最新研究进展：马与其他物种有何不同？
Bart Leemans,Tom A E Stout,Catharina De Schauwer et al.
Bart Leemans et al.
In contrast to various other mammalian species, conventional in vitro fertilization (IVF) with horse gametes is not reliably successful. In particular, stallion spermatozoa fails to penetrate the zona pellucida, most likely due to incomplet...