Julia Kim,Emre Seli
Julia Kim
Mitochondria play an essential role in generating energy for embryo development and maintaining embryo metabolism through key cellular functions including ion homeostasis, amino acid metabolism, glycolysis, fatty acid metabolism, signal tra...
FERTILITY PRESERVATION: Testicular transplantation for fertility preservation: clinical potential and current challenges [0.03%]
生育力保存：睾丸移植在生育力保存中的临床潜力及目前挑战
Karen R Kilcoyne,Rod T Mitchell
Karen R Kilcoyne
Transplantation of testicular tissues and cells has been proposed as a future clinical option for patients who have had testicular tissue cryopreserved prior to receiving gonadotoxic therapies. Whilst this approach remains experimental, suc...
Unraveling the connection between GABA and kisspeptin in the control of reproduction [0.03%]
解开GABA与kisspeptin在生殖控制中的联系
Noelia P Di Giorgio,Marianne Bizzozzero-Hiriart,Carlos Libertun et al.
Noelia P Di Giorgio et al.
Neuroendocrine control of reproduction involves the interplay of various factors that become active at some point along development. GnRH is the main neurohormone controlling reproduction and among the most important inputs modulating GnRH ...
Transcriptional status of mouse oocytes corresponds with their ability to generate Ca2+ release [0.03%]
小鼠卵母细胞转录状态与其产生钙离子释放的能力相对应
Monika Fluks,Katarzyna Szczepanska,Takao Ishikawa et al.
Monika Fluks et al.
In fully grown ovarian follicles both transcriptionally active (NSN) and inactive (SN) oocytes are present. NSN oocytes have been shown to display lower developmental potential. It is possible that oocytes that have not completed transcript...
Glucose regulates the histone acetylation of gene promoters in decidualizing stromal cells [0.03%]
葡萄糖通过调节蜕膜细胞基因启动子处组蛋白乙酰化发挥功能
Kosuke Jozaki,Isao Tamura,Haruka Takagi et al.
Kosuke Jozaki et al.
Decidualization stimuli activate the insulin signaling pathway and increase the glucose uptake in human endometrial stromal cells (ESCs). The inductions of prolactin (PRL) and IGF-binding protein-1 (IGFBP1), specific markers of decidualizat...
VIP activates primordial follicles of rat through ERK-mTOR pathway in tissue culture [0.03%]
VIP通过ERK-mTOR信号活化组织培养大鼠原始卵泡的研究
Song Li,Qi Fan,Yanqiu Xie et al.
Song Li et al.
In vitro activation of primordial follicles is becoming more essential in assisted reproductive technologies. Vasoactive intestinal peptide (VIP) is one of the members of the neurotrophin family which has demonstrated to have an impact on f...
Guangyin Xi,Wenjing Wang,Sarfaraz A Fazlani et al.
Guangyin Xi et al.
Compared to ovarian antral follicle development, the mechanism underlying preantral follicle growth has not been well documented. Although C-type natriuretic peptide (CNP) involvement in preantral folliculogenesis has been explored, its det...
Inhibition of DNA repair protein RAD51 affects porcine preimplantation embryo development [0.03%]
DNA修复蛋白RAD51的抑制影响猪胚胎植入前发育
Zhe-Long Jin,Xing-Hui Shen,Liang Shuang et al.
Zhe-Long Jin et al.
Homologous recombination (HR) plays a critical role in facilitating replication fork progression when the polymerase complex encounters a blocking DNA lesion, and it also serves as the primary mechanism for error-free DNA repair of double-s...
Gestational nutrition 1: alterations to gestational nutrition can increase indicators of fertility in sheep [0.03%]
妊娠营养对妊娠营养进行调整可以增加母羊的生育指标
Peter Smith,Jo-Ann L Stanton,Laurel Quirke et al.
Peter Smith et al.
The aim of this study was to examine the relationships between gestational nutrition, fetal ovarian development and offspring fertility in female sheep and to highlight the potential mechanisms underlying these relationships. Adult sheep (n...
Gastrointestinal capacity, gut hormones and appetite change during rat pregnancy and lactation [0.03%]
大鼠妊娠和哺乳期胃肠容积、肠激素和摄食量的变化
Michelle L Johnson,M Jill Saffrey,Victoria J Taylor
Michelle L Johnson
Pregnancy and lactation increase maternal appetite and adiposity, which in humans can lead to long-term body mass retention. Previous rat reproduction studies suggest that appetite-inhibiting gut hormone, peptide-YY (PYY), is elevated, desp...