NUP62: the target of an anti-sperm auto-monoclonal antibody during testicular development [0.03%]
NUP62：在睾丸发育过程中抗精子自身单克隆抗体的作用靶点
Risako Oda-Sakurai,Hiroshi Yoshitake,Yoshiki Miura et al.
Risako Oda-Sakurai et al.
Ts4, an autosperm-monoclonal antibody (mAb), reacts with a specific oligosaccharide (OS) of glycoproteins containing bisecting N-acetylglucosamine residues. Ts4 reactivity was observed against epididymal spermatozoa, testicular germ cells, ...
Bioactive fragments of laminin and collagen chains: lesson from the testis [0.03%]
纤溶酶作用的层粘连蛋白和胶原多肽片段的生物学活性及其对生精细胞的影响
Huitao Li,Shiwen Liu,Siwen Wu et al.
Huitao Li et al.
Recent studies have shown that the testis is producing several biologically active peptides, namely the F5- and the NC1-peptides from laminin-γ3 and collagen α3 (IV) chain, respectively, that promotes blood-testis barrier (BTB) remodeling...
FERTILITY PRESERVATION: Progress and prospects for developing human immature oocytes in vitro [0.03%]
体外发育人卵母细胞的研究进展与前景
Evelyn E Telfer
Evelyn E Telfer
Ovarian cryopreservation rapidly developed from basic science to clinical application and can now be used to preserve the fertility of girls and young women at high risk of sterility. Primordial follicles can be cryopreserved in ovarian cor...
miR-21-3p inhibits autophagy of bovine granulosa cells by targeting VEGFA via PI3K/AKT signaling [0.03%]
miR-21-3p通过PI3K/AKT信号靶向VEGFA抑制牛颗粒细胞自噬
Lizhu Ma,Yuxin Zheng,Xiaorong Tang et al.
Lizhu Ma et al.
It is well documented that granulosa cell apoptosis is the main reason for follicular atresia and death; however, increasing evidence suggests that autophagy plays an important role in the fate of granulosa cells. miR-21-3p regulates many f...
Early embryonic development of bovine oocytes challenged with LPS in vitro or in vivo [0.03%]
体外或体内受到LPS刺激的牛卵母细胞早期胚胎发育特性研究
Joao Alveiro Alvarado Rincón,Patricia Carvalho Gindri,Bruna Mion et al.
Joao Alveiro Alvarado Rincón et al.
The aim of this study was to evaluate the effect of exposing bovine oocytes to lipopolysaccharides (LPS) in vivo and in vitro on early embryo development. In experiment 1, cumulus oocyte complexes (COCs, n = 700/group) were challenged with ...
The role of the adiponectin system in acute fasting-impaired mouse ovaries [0.03%]
急性禁食致小鼠卵巢损伤与脂联素系统的相关性研究
Yingying Han,Shuhao Zhang,Haotong Zhuang et al.
Yingying Han et al.
Adiponectin (ADIPOQ, encoded by Adipoq) is an important white adipose-derived adipokine linked to energy homeostasis and reproductive function. This study aims to reveal the expression and role of the adiponectin system in the ovaries under...
NLRP7 is expressed in the ovine ovary and associated with in vitro pre-implantation embryo development [0.03%]
NLRP7在羊卵巢中的表达及其与体外早期胚胎发育的关系
Guangdong Li,Xiuzhi Tian,Dongying Lv et al.
Guangdong Li et al.
NLRP (NACHT, LRR and PYD domain-containing proteins) family plays pivotal roles in mammalian reproduction. Mutation of NLRP7 is often associated with human recurrent hydatidiform moles. Few studies regarding the functions of NLRP7 have been...
Melatonin rescues impaired penetration ability of human spermatozoa induced by mitochondrial dysfunction [0.03%]
褪黑素可缓解线粒体功能障碍诱导的人类精子穿透能力下降现象
Xue-Ying Zhang,Yi-Meng Xiong,Ya-Jing Tan et al.
Xue-Ying Zhang et al.
Fertilization failure often occurs during in vitro fertilization (IVF) cycles despite apparently normal sperm and oocytes. Accumulating evidence suggests that mitochondria play crucial roles in the regulation of sperm function and male fert...
The rete testis harbors Sertoli-like cells capable of expressing DMRT1 [0.03%]
rete testis中含有能够表达DMRT1的Sertoli样细胞
Ekaterina A Malolina,Andrey Yu Kulibin
Ekaterina A Malolina
Sertoli cells (SCs) are supporting cells in the mammalian testis that proliferate throughout fetal and postnatal development but exit the cell cycle and differentiate at puberty. In our previous study, we isolated a population of highly pro...
Drosophila melanogaster as a model for nutrient regulation of ovarian function [0.03%]
果蝇的营养调节卵功能模型机制研究
Alissa Richmond Armstrong
Alissa Richmond Armstrong
Observed in a wide variety of organism, from invertebrates to mammals, nutritional status modulates the energetically costly effort of producing female gametes. Despite this long-standing link between nutrition and ovarian function, relativ...