Morphofunctional evaluation of gametogenesis in the endemic South Atlantic reef-builder Mussismilia harttii [0.03%]
南大西洋特有礁石建造者拟缨红珊瑚(Mussismilia harttii)配子发生morpho功能评价
Wanderson Valente,Bárbara Ramalho Ladeira Cardoso,Francisco de Assis Pinheiro Cotrim et al.
Wanderson Valente et al.
Decline of coral reefs worldwide emphasizes the need for biological information to subside species conservation and management strategies. Herein, we thoroughly explored gametogenesis of the endemic and endangered Brazilian coral Mussismili...
Epigallocatechin-3-Gallate Mitigates Postovulatory Oocyte Aging by Reducing Oxidative Stress and Promoting Embryonic Development [0.03%]
表没食子儿茶素没食子酸酯通过减少氧化应激和促进胚胎发育来缓解卵母细胞老化
Ling Gong,Ruo Nan Fan,Jia Peng et al.
Ling Gong et al.
Oxidative stress-mediated postovulatory aging (POA) significantly compromises oocyte quality and impairs subsequent embryonic developmental competence, thereby reducing the efficiency of assisted reproductive technologies (ART) and livestoc...
Lauren Fletcher,Xiaoshu Zhan,Yashu Song et al.
Lauren Fletcher et al.
There is a need for reliable and effective biomarkers of female fertility and reproductive potential in the pork industry as current selection protocols are not keeping up with the rate of improvement for other production-related traits. Th...
Disrupted MOS signaling alters meiotic cell cycle regulation and the egg transcriptome [0.03%]
MOS信号转导受损会干扰减数分裂细胞周期调控和卵母细胞的基因表达谱
Gisela Cairo,Olha Kholod,Olivia Palmer et al.
Gisela Cairo et al.
Mammalian female meiosis is tightly regulated to produce a developmentally competent egg. Oocytes enter meiosis in the fetal ovary and then arrest at prophase I until sexual maturation. Upon hormonal stimulation, a subset of oocytes resumes...
Male reproductive tract extracellular vesicles display region-specific heterogeneity in mice [0.03%]
小鼠雄性生殖道外泌体的区域特异性异质性
Vipul Batra,Hannah L Morgan,Katie K Choi et al.
Vipul Batra et al.
As sperm transit the male reproductive tract, they undergo a series of dynamic changes, gaining motility, modifying lipid and protein content and refining their epigenetic composition. Extracellular vesicles are central to this post-testicu...
GATA3 is not required for sheep trophectoderm development, but it plays a role in post-hatching epiblast survival [0.03%]
GATA3不是羊滋养层发育所必需的，但其对孵化后外胚层存活有作用
Nuria Martínez de Los Reyes,Inés Flores-Borobia,Leopoldo González-Brusi et al.
Nuria Martínez de Los Reyes et al.
Early embryo mortality represents a major challenge in livestock production, leading to significant economic losses. However, the molecular determinants underpinning early embryo development in these species remain poorly understood. GATA3 ...
Superovulation Induced Changes in Murine Ovarian Perifollicular Angiogenesis [0.03%]
超排卵诱发的小鼠卵巢囊周血管生成变化
Georgia Mappa,Nicole G Barbieri,Clare Freer et al.
Georgia Mappa et al.
Superovulation is widely used to maximise oocyte/embryo yield in animal models. However, it has been implicated in disrupting normal follicular development, potentially affecting perifollicular angiogenesis. This study investigated the impa...
Extracellular vesicles, Syntaxin 2 and SNAP23 in the uterine microenvironment of the rat [0.03%]
大鼠子宫微环境中的细胞外囊泡、Syntaxin 2 和 SNAP23
Sadaf N Kalam,Samson N Dowland,Louise Cole et al.
Sadaf N Kalam et al.
Uterine luminal fluid is composed of secretions from the uterine luminal and glandular epithelial cells. The fluid composition plays a role in cell-to-cell communication between the receptive endometrium and an invading blastocyst. Part of ...
Laura C Torchen,Margaret Wu,Brianna Thompson et al.
Laura C Torchen et al.
Functional adrenal hyperandrogenism is a common feature of PCOS, observed in roughly 20-30% of affected women. The mechanisms of adrenal hyperandrogenism in PCOS require additional clarification, but seem to be related to increased adrenal ...
Maternal Pre-pregnancy Risks and Postpartum Consequences of Gestational Diabetes [0.03%]
妊娠期糖尿病的孕前风险及产后后果
Kathryn M Storey,Lena Shay,Truman Poteat et al.
Kathryn M Storey et al.
Gestational Diabetes Mellitus (GDM) is defined as glucose intolerance that arises during pregnancy. It can be caused by excess insulin resistance, a failure to augment insulin secretion in response to pregnancy, or both. The risk of develop...