Mitochondrial uncoupling proteins regulate the metabolic function of human Sertoli cells [0.03%]
线粒体解偶联蛋白调节人支持细胞的代谢功能
David F Carrageta,Laís Freire-Brito,Bárbara Guerra-Carvalho et al.
David F Carrageta et al.
In brief: Mitochondrial uncoupling proteins (UCPs) regulate mitochondrial activity and reactive oxygen species production through the transport of protons and metabolites. This study identified the expression of UCPs in h...
Ultrastructural cilia defects in multi-ciliated uterine glandular epithelial cells from women with reproductive failure [0.03%]
不孕女性输卵管上皮细胞纤毛的超微结构缺陷
Jennifer E Pearson-Farr,Regan Doherty,David S Chatelet et al.
Jennifer E Pearson-Farr et al.
In brief: The causes of subfertility and recurrent pregnancy loss are often unclear. This study shows that endometrial gland cilia from women with subfertility have ultrastructural defects. ...
Adipolin (C1QTNF12) is a new adipokine in female reproduction: expression and function in porcine granulosa cells [0.03%]
脂肪细胞因子adipolin(C1QTNF12)在雌性生殖中作用的研究：猪颗粒细胞的表达与功能研究
Alix Barbe,Patrycja Kurowska,Christelle Rame et al.
Alix Barbe et al.
In brief: Adipolin (C1QTNF12) has been described as a regulator of metabolism and is linked with the pathophysiology of PCOS. In this study, for the first time, we show the expression of C1QTNF12 in granulosa cells and it...
Downregulation of CRHBP is associated with trophoblast invasion inhibition in recurrent pregnancy loss [0.03%]
CRHBP下调与复发性妊娠丢失相关合体细胞侵袭抑制有关
Fengrun Sun,Liyuan Cui,Jinfeng Qian et al.
Fengrun Sun et al.
In brief: Corticotropin-releasing hormone binding protein (CRHBP) is fundamental to the stress response and plays an important role in parturition during pregnancy. This study shows that abnormal CRHBP expression could be...
Transcriptional profiling of Kiss1 neurons from arcuate and rostral periventricular hypothalamic regions in female mice [0.03%]
雌性小鼠下丘脑弓核和背侧室周核Kiss1神经元的转录组学特征分析
Stephen Manchishi,Malwina Prater,William Henry Colledge
Stephen Manchishi
In brief: The transcriptional profiles of Kiss1 neurons from the arcuate and the rostral periventricular region of the third ventricle of the hypothalamus have been directly compared in diestrous female mice. Differential...
Effect of vitrification on protein O-GlcNAcylation in mouse metaphase II oocytes [0.03%]
玻璃化冷冻对小鼠MII卵母细胞蛋白质O-连接的N-乙酰氨基葡萄糖基化的效应
Kang Zhang,Tianyang Lan,Feifei Lin et al.
Kang Zhang et al.
In brief: Oocyte vitrification leads to DNA hypomethylation, which results in defect in early embryo development. This study reveals that oocyte vitrification impairs the DNA methylation pattern by influencing protein O-G...
The dogma of the sterile uterus revisited: does microbial seeding occur during fetal life in humans and animals? [0.03%]
重新审视“无菌子宫”信条：人类和动物在胎儿期是否会发生微生物定植？
Penelope Banchi,Barbara Colitti,Geert Opsomer et al.
Penelope Banchi et al.
In brief: Opposing conclusions have been drawn regarding the presence of viable bacteria in the healthy pregnant uterus. Current evidence in humans and animals suggests that fetomaternal tissues present only traces of bac...
Maternal age, obesity and hyperglycaemia are associated with a delay in preimplantation embryo development in mouse [0.03%]
高龄、肥胖和高血糖可导致小鼠前胚胎发育延迟
Joaquín Lilao-Garzón,Yeray Brito-Casillas,Oscar Quesada-Canales et al.
Joaquín Lilao-Garzón et al.
In brief: Fertility has decreased due to advanced maternal age and the rising prevalence of the metabolic syndrome. Using quantitative image analysis methods, we show that these factors are associated with delayed preimpl...
Thomas Bernd Hildebrandt,Susanne Holtze,Silvia Colleoni et al.
Thomas Bernd Hildebrandt et al.
In brief: To save endangered rhinoceros species, assisted reproductive technologies are warranted. We here report in vitro blastocyst generation of the Near-Threatened Southern white rhinoceros and, for the first time, al...
Thomas Bernd Hildebrandt,Susanne Holtze,Silvia Colleoni et al.
Thomas Bernd Hildebrandt et al.
In brief: To save endangered rhinoceros species, assisted reproductive technologies are warranted. We here report in vitro blastocyst generation of the Near-Threatened Southern white rhinoceros and, for the first time, al...