Zoe M G Skalkos,James U Van Dyke,Samson N Dowland et al.
Zoe M G Skalkos et al.
In brief: Seahorses exhibit male pregnancy and are thus valuable comparative models for the study of the physiology and evolution of pregnancy. This study shows that protein is transported from fathers to developing embry...
PPAR-gamma influences developmental competence and trophectoderm lineage specification in bovine embryos [0.03%]
PPAR-gamma影响牛胚胎的发育能力和滋养层谱系的特化
Maura S McGraw,Sandeep K Rajput,Bradford W Daigneault
Maura S McGraw
In brief: Peroxisome proliferator-activated receptor gamma (PPARG) is a critical regulator of placental function, but earlier roles in preimplantation embryo development and embryonic origins of placental formation have n...
The central role of pyruvate metabolism on the epigenetic maturation and transcriptional profile of bovine oocytes [0.03%]
丙酮酸代谢在牛卵母细胞表观遗传成熟和转录谱中的中心作用
João Vitor Alcantara da Silva,Jessica Ispada,Ricardo Perecin Nociti et al.
João Vitor Alcantara da Silva et al.
In brief: Pyruvate metabolism is one of the main metabolic pathways during oocyte maturation. This study demonstrates that pyruvate metabolism also regulates the epigenetic and molecular maturation in bovine oocytes. ...
BMAL1 positively correlates with genes regulating steroidogenesis in human luteinized granulosa cells [0.03%]
BMAL1正向关联人类黄体颗粒细胞中调节类固醇生成的基因
Tomomi Kawamura,Yidan Dai,Masanori Ono et al.
Tomomi Kawamura et al.
In brief: In this study, we examined the relationship between BMAL1 expression and the genes regulating steroid biosynthesis in human luteinized granulosa cells. BMAL1 function is crucial for steroid production and proper...
Endocannabinoid regulation in the cervix during pregnancy: insights into molecular mechanisms of premature labor [0.03%]
妊娠期间子宫颈内大麻素的调节作用：关于早产分子机制的启示
Carolina Marvaldi,Felisa Herrero,Clare Johnson et al.
Carolina Marvaldi et al.
In brief: The cervix plays a crucial role not only in the maintenance of pregnancy but also during delivery, when it undergoes extensive changes. This study highlights the involvement of the endocannabinoidome in cervical...
Morphological analysis of the human sperm tail during the early post-fertilization stage [0.03%]
人类精子尾部在早期着床阶段的形态学分析
Yoshiteru Kai,Hachiro Iseki,Takeshi Matsui et al.
Yoshiteru Kai et al.
After fertilization, the human sperm tail lost its fibrous sheath at the pronuclear stage to become coiled and then attached to one of the first mitotic spindle poles. The tip of the sperm tail was branched and its degree did not change fro...
Long-lasting effects of the presence of male siblings in utero on subsequent reproductive performance [0.03%]
子宫内存在兄弟的长期影响对随后的生育表现的影响
Mathieu Douhard,Victor Ronget,Frédéric Douhard
Mathieu Douhard
Laboratory studies with rodents indicate that in utero proximity of a female to male foetus can affect female's subsequent reproduction due to elevated testosterone exposure during early development. It remains unknown whether these finding...
Decreased NSD2 impairs stromal cell proliferation in human endometrium via reprogramming H3K36me2 [0.03%]
NSD2的减少通过重编程H3K36me2而损害子宫内膜基质细胞的增殖
Chuan-Mei Qin,Xiao-Wei Wei,Jia-Yi Wu et al.
Chuan-Mei Qin et al.
In brief: The proliferation of the endometrium is regulated by histone methylation. This study shows that decreased NSD2 impairs proliferative-phase endometrial stromal cell proliferation in patients with recurrent implan...
Vakil Ahmad,Sai Goutham Reddy Yeddula,Bhanu Telugu et al.
Vakil Ahmad et al.
The uterine epithelium is composed of a single layer of hormone responsive polarized epithelial cells that line the lumen and form tubular glands. Endometrial epithelial organoids (EEO) can be generated from uterine epithelia and recapitula...
The press-assisted fusion scheme significantly mitigates the quantity of HVJ-E required in mitochondrial replacement techniques [0.03%]
presses-assisted融合方案显著减少了线粒体替代技术中所需的HVJ-E的数量
Meng Ma,Shutian Jiang,Wei Jin et al.
Meng Ma et al.
In brief: The impact of HVJ-E employed in mitochondrial replacement techniques (MRTs) on embryonic development remains uncertain. This study has exhibited the influence of HVJ-E utilized in MRTs on embryonic development and has devised a no...