Unveiling the intricate hormonal regulation of asprosin and its receptor in the mice testis [0.03%]
揭秘小鼠睾丸中Asproin及其受体的复杂激素调节机制
Ananya Banerjee,Vishesh Chauhan,Sangeeta Maurya et al.
Ananya Banerjee et al.
In brief: Asprosin is reported to regulate testicular functions directly as well as through the modulation of gonadotropin and sex steroid levels; however, hormonal regulation of testicular asprosin and its receptor, Olfr...
Daniel A Dumesic,Vasantha Padmanabhan,David H Abbott
Daniel A Dumesic
GDF-11 stimulates human extravillous trophoblast cell invasion by upregulating ANGPTL4 expression [0.03%]
GDF-11通过上调ANGPTL4的表达促进人合体滋养细胞侵袭能力
Ze Wu,Lanlan Fang,Xuan Dang et al.
Ze Wu et al.
In brief: How extravillous trophoblast (EVT) invasion is regulated during placental development remains an important question in reproductive biology. This study demonstrates that growth differentiation factor-11 (GDF-11)...
Age and physical activity modulate miRNAs contained in human follicular fluid extracellular vesicles [0.03%]
年龄和体力活动调节人卵泡液胞外囊泡中的miRNA
Maria Soares,Carmen Almiñana,Ana Filipa Ferreira et al.
Maria Soares et al.
In brief: Aging and lifestyle interventions alter extracellular vesicle cargo in fluids. In human follicular fluid, the miRNA content of extracellular vesicles is altered with aging and physical activity. ...
Cold shock, chilling and cryopreservation impact sperm proteasome function [0.03%]
冷刺激、低温保存及冷冻对精子蛋白酶体功能的影响
Grace Voss,Mikayla Crouch,Michal Zigo et al.
Grace Voss et al.
In brief: Preservation of sperm, while successful in many species, can lead to molecular changes which make artificial insemination less successful. This study explores changes to proteasome function caused by chilling an...
Active vitamin D3 reduces testicular tissue damage and inflammation in mice with autoimmune orchitis [0.03%]
活性维生素D3可减轻自身免疫性睾丸炎小鼠的睾丸组织损伤和炎症反应
Cecilia Valeria Pérez,Patricia Verónica Jacobo,Martín Javier Pizzini et al.
Cecilia Valeria Pérez et al.
In brief: Chronic inflammation of the male reproductive tract is a relevant cause of infertility. This study demonstrates for the first time that vitamin D3, administered in a therapeutic protocol, attenuates testicular i...
Ram sperm and seminal plasma alter immune transcriptome and cytokine secretion in ovine cervical explants ex vivo [0.03%]
ram精子和精浆会影响山羊宫颈组织的免疫基因表达和细胞因子分泌
Jessica P Rickard,Sophie Warr,Simon P de Graaf et al.
Jessica P Rickard et al.
In brief: Cervical explants alter gene expression and cytokine secretion in response to seminal plasma compared with spermatozoa alone. Results validate the model to study mechanisms behind sperm-immune tolerance in the o...
The late chromatoid body component TSSK2 is involved in translational regulation in elongating spermatids in mice [0.03%]
TSSK2参与小鼠延长型精子细胞的翻译调控
Mari S Lehti,Lin Ma,Salli Kärnä et al.
Mari S Lehti et al.
In brief: Temporally regulated translation is critical for late steps of spermatogenesis due to transcriptional silencing during chromatin condensation. This study shows that the function of the cytoplasmic granule, the l...
PREGNANCY DISORDERS AND MATERNAL CONSEQUENCES: Postpartum mental health after medically complicated pregnancy [0.03%]
妊娠并发症与母亲健康结局：医学病理性妊娠后的产后心理健康
Lynne M Roberts,Megan Gow,Bronwyn Graham et al.
Lynne M Roberts et al.
In brief: Pregnancy complications such as hypertensive disorders, gestational diabetes mellitus, and anaemia may increase the risk of postpartum mental disorders, especially depression; however, the evidence for anxiety a...
Centrosomes regulate pronuclear apposition ensuring parental genome unification in cattle [0.03%]
中心体通过调控雌雄原核融合确保牛的雌雄基因组统一化
Yuki Takada,Shu Hashimoto,Yoshiharu Morimoto
Yuki Takada
In brief: Mammalian zygotes often fail to unify their genomes. This study showed that the position of the centrosome is crucial for regulation of pronuclear apposition and genome unification. ...