Gestational giant panda plasma metabolomics: amino acid metabolism characteristic may predict panda pregnancy outcomes [0.03%]
妊娠大熊猫血浆代谢组学：氨基酸代谢特征可预测大熊猫的妊娠结局
Wen Zheng,Liang Zhang,Kailai Cai et al.
Wen Zheng et al.
There has been remarkable progress in the conservation and reproduction of giant pandas. However, the physiology of the gestation period in pandas remains poorly understood. The metabolic processes from estrus to pregnancy are dynamic and p...
L-Carnitine sustainably affects bioenergetic profile of bovine blastocysts and transcriptome profile of elongation-stage embryos [0.03%]
牛胚泡的生物能量谱和延展期胚胎转录组受左旋肉碱的影响
Eva Held-Hoelker,Jessica Kurzella,Dessie Salilew-Wondim et al.
Eva Held-Hoelker et al.
L-Carnitine (LC) is known to play key roles in lipid metabolism and antioxidative activity, implicating enhanced cryotolerance of bovine blastocysts. However, sustainability of LC supplementation during culture period on preimplantation dev...
Dual role of valosin-containing protein (VCP/p97) in mouse sperm during capacitation [0.03%]
VCP/p97在小鼠精子获能过程中的双重作用
Martina Jabloñski,Florenza A La Spina,Liza J Schiavi-Ehrenhaus et al.
Martina Jabloñski et al.
Valosin-containing protein (VCP; aka p97), a member of the AAA (ATPases Associated with various cellular Activities) family, has been associated with a wide range of cellular functions. While previous evidence has shown its presence in mamm...
3D hUC-MSC spheroids exhibit superior resistance to autophagy and apoptosis of granulosa cells in POF rat model [0.03%]
人子宫内膜间充质干细胞球状体通过抑制颗粒细胞自噬和凋亡修复卵巢早衰损伤
Wenjie Dai,Hong Yang,Bo Xu et al.
Wenjie Dai et al.
In brief: This study reveals that orthotopic transplantation of 3D hUC-MSC spheroids is more effective than monolayer-cultured hUC-MSCs in improving POF and distinctly reducing oxidative stress through the paracrine effec...
Heterogeneity of Ovarian Matrisome Hydrogels Elucidates Factors that May Influence Follicle Growth in Vitro [0.03%]
卵巢基质胶的异质性阐明了可能影响体外卵泡生长的因素
Hannah B McDowell,Nathaniel F Henning,Monica M Laronda
Hannah B McDowell
This work describes a valuable and reproducible method for generating optically clear bovine ovary-derived hydrogels that support in vitro murine follicle growth. These techniques are the foundation in which follicle growth dynamics and mat...
Hamster spermatozoa incorporate hypotaurine via TauT for self-protection [0.03%]
仓鼠精子通过TauT摄取低 tau 赖氨酸以进行自我保护
Gen L Takei,Yasuhiro Horibata,Fubito Toyama et al.
Gen L Takei et al.
In brief: Mammalian spermatozoa actively generate reactive oxygen species (ROS) during capacitation, a maturational process necessary for fertilization in vivo. This study shows that hypotaurine, a precursor of taurine pr...
IMPACT OF REAL-LIFE ENVIRONMENTAL EXPOSURES ON REPRODUCTION: Biosolids and male reproduction [0.03%]
实际环境暴露对生殖的影响：污泥和男性生育能力
Michelle Bellingham,Neil Evans
Michelle Bellingham
Over the past 50 years, there has been a concerning decline in male reproductive health and an increase in male infertility which is now recognised as a major health concern globally. While male infertility can be linked to some genetic and...
Atrazine disorganises laminin formation and reduces cell numbers in the tammar testis during early differentiation [0.03%]
阿特拉津扰乱有袋动物睾丸早期分化期层粘连蛋白形成并减少细胞数量
Yu Chen,Jaiden Lay,Geoffrey Shaw et al.
Yu Chen et al.
In brief: Atrazine, like oestrogen, disorganises laminin formation and reduces the number of germ cells and Sertoli cells in the developing testes of the tammar wallaby. This study suggests that interfering with the balan...
GRSF1 deficiency attenuates mitochondrial function in aging granulosa cells [0.03%]
GRSF1缺乏通过削弱颗粒细胞线粒体功能促进卵巢早衰
Canxin Wen,Linlin Jiang,Ping Pan et al.
Canxin Wen et al.
In brief: Ovarian aging results in reactive oxygen species accumulation and mitochondrial deterioration. During the aging process, GRSF1 deficiency attenuates mitochondrial function in aging granulosa cells. ...
METTL3-dependent m6A modification facilitates decreased endometrial decidualization via attenuation MET in endometriosis [0.03%]
METTL3介导的m6A修饰通过抑制MET促进子宫内膜异位症中子宫内膜蜕膜化降低的作用机制研究
Wenqian Xiong,Jie Jin,Yi Liu
Wenqian Xiong
Mesenchymal-epithelial transition (MET)-mediated endometrial decidualization is pivotal for achieving endometrial receptivity and successful pregnancy. We observed blockade of MET in the eutopic secretory endometrium of patients with endome...