IMPACT OF REAL-LIFE ENVIRONMENTAL EXPOSURES ON REPRODUCTION: Systemic and ovarian impacts of heat stress in the porcine model [0.03%]
现实环境暴露对生殖的影响:猪模型中热应激的全身和卵巢影响
Aileen F Keating,Jason W Ross,Lance H Baumgard
Aileen F Keating
In brief: This review describes how heat stress causes systemic endocrine and metabolic alterations that contribute to intracellular ovarian perturbations, resulting in female infertility. ...
IMPACT OF REAL-LIFE ENVIRONMENTAL EXPOSURES ON REPRODUCTION: A contemporary review of machine learning to predict adverse pregnancy outcomes from pharmaceuticals, including DDIs [0.03%]
现实环境暴露对生殖的影响:综述利用机器学习预测药品(包括药物相互作用)导致不良妊娠结局的方法
Julie Gardella,Dimitri Abrahamsson,Judith Zelikoff
Julie Gardella
In brief: Clinical drug trials often do not include pregnant people due to health risks; therefore, many medications have an unknown effect on the developing fetus. Machine learning QSAR models have been used successfully...
IMPACT OF REAL-LIFE ENVIRONMENTAL EXPOSURES ON REPRODUCTION: Rodent reproductive behavior among males and females after exposure to endocrine-disrupting chemicals [0.03%]
环境暴露对生殖的影响:暴露于干扰素后雄性和雌性鼠的生殖行为
Jacob R Maxon,Megan M Mahoney
Jacob R Maxon
In brief: The rodent reproductive behavioral control column of the hypothalamus and the hypothalamic-pituitary-gonadal (HPG) axis are critical systems that regulate copulatory behaviors in both males and females. We revie...
Fecundity difference is related to the production of reproductive pheromones in rats [0.03%]
生育率差异与大鼠繁殖信息素的产生有关
Toshiyuki Yamada,Aya Ando,Ryusuke Morita et al.
Toshiyuki Yamada et al.
In brief: Social and reproductive behaviors in mammals are regulated by pheromones. This study shows the possibility that male extraorbital lacrimal gland-derived pheromones are involved in reproductive efficiency in rats...
REPRODUCTIVE HEALTH IN TRANS AND GENDER-DIVERSE PATIENTS: Gonadal tissue cryopreservation in transgender and gender-diverse people [0.03%]
跨性别和性别多样患者的生殖健康:跨性别和性别多样化人群的性腺组织冷冻保存
Chatchanan Ausavarungnirun,Kyle E Orwig
Chatchanan Ausavarungnirun
In brief: Gender-affirming treatments for gender dysphoria can impact fertility. This review describes the impact of gender-affirming treatments on fertility and options to preserve fertility in transgender or gender-dive...
Hypoxia-induced autophagy inhibits myometrial proliferation in pregnant mice via the mTOR pathway in vitro [0.03%]
缺氧诱导的自噬通过mTOR途径抑制妊娠小鼠子宫平滑肌细胞增殖
Xingxing Wang,Huihui Yu,Xuan Li et al.
Xingxing Wang et al.
In brief: During pregnancy and delivery, the myometrium was affected by hypoxia stress, which acts as a regulator of cell proliferation. The proliferation of uterine smooth muscle cells in pregnant mice was inhibited unde...
SON controls mouse early embryonic development by regulating RNA splicing and histone methylation [0.03%]
SON通过调控RNA拼接和组蛋白甲基化控制小鼠早期胚胎发育
Jiarui Wei,Xianglan An,Cong Fu et al.
Jiarui Wei et al.
In brief: During zygotic genome activation, thousands of genes are activated, and those pre-mRNAs must be accurately spliced to support the production of functional proteins. This study shows that SON is necessary for pro...
Reproductive health in trans and gender diverse patients: Transgender medicine: contextual trans gynecology [0.03%]
变性人和性别多样性患者的生殖健康: transgender医学:背景下的trans妇科学
Mick van Trotsenburg
Mick van Trotsenburg
In brief: This manuscript aims to promote an understanding of the special needs of transgender and gender-diverse people by putting trans gynecology into context. By definition, medical interventions for transgender peopl...
REPRODUCTIVE HEALTH IN TRANS AND GENDER-DIVERSE PATIENTS: Psychosocial counseling of transgender and gender-diverse individuals in fertility and reproductive medicine: a narrative review [0.03%]
变性人和性别多样患者的生育与生殖医学中的心理社会咨询:叙述性综述
Peter Cummings,Angela Lawson
Peter Cummings
In brief: Transgender and gender-diverse (TGD) people have similar desires for parenting as cisgender individuals but are likely to face greater barriers in accessing fertility treatment than their cisgender peers. Mental...
REPRODUCTIVE HEALTH IN TRANS AND GENDER DIVERSE PATIENTS: Mind the gap: a nationwide audit of LGBTQ+ inclusion in fertility care providers in the United Kingdom [0.03%]
英国生殖机构对LGBTQ+人群的包容情况调查:我们注意到性别多样性和变性患者生殖医疗保健方面的差距
Chloe He,Nour Al-Maani,Mei Francis et al.
Chloe He et al.
In brief: We describe a first-of-its-kind audit of LGBTQ+ inclusivity in fertility care providers across the United Kingdom. Despite efforts being made to improve LGBTQ+ inclusion in fertility care, our results paint a pi...