One size doesn't fit all: female-male interactions on the path to fertilization [0.03%]
一把尺子量不出多样性:受精之路的雌雄互作大小不一
Léa Daupagne,Lennart Winkler,Matilda Q R Pembury-Smith et al.
Léa Daupagne et al.
Extensive research indicates that fertilization outcomes are shaped by individual female and male traits that reflect their intrinsic quality. Yet, surprisingly little is known about the influence of interactions between the sexes and their...
Gene expression profile analysis of subregions of the adult female reproductive tract in the brown anole, Anolis sagrei [0.03%]
短吻蝘蜓(Anolis sagrei)成年雌性生殖道亚区基因表达谱分析
Bonnie K Kircher,Bin Liu,Matthew D Bramble et al.
Bonnie K Kircher et al.
The morphological diversity and functional role of the organs of the female reproductive system across tetrapods (limbed vertebrates) are relatively poorly understood. Though some features are morphologically similar, species-specific modif...
Metabolic syndrome impairs endometrial functioning and early pregnancy: an in vivo study [0.03%]
代谢综合征影响子宫内膜功能和早期妊娠的一项体内研究
Noelia Carnovale,Candela Velazquez,Sofía Del Valle et al.
Noelia Carnovale et al.
Metabolic syndrome (MS) is increasingly associated with impaired reproductive health. This study aimed to assess the endometrial characteristics and reproductive outcomes of a female MS mouse model and evaluate metformin's therapeutic effec...
Phthalates Disrupt Female Reproductive Health: A Call for Enhanced Investigation into Mixtures [0.03%]
邻苯二甲酸盐扰乱女性生殖健康:混合物的增强调查势在必行
Katie L Land,Sundus M Ghuneim,Brittney A Williams et al.
Katie L Land et al.
Daily exposure to a mixture of phthalates is unavoidable in humans and poses a risk to reproductive health because they are known endocrine-disrupting chemicals. Specific to female reproductive health, the literature has linked phthalate ex...
Non-canonical spatial organization of heterochromatin in mouse preimplantation embryos [0.03%]
小鼠着床前胚胎异染色质的非典型空间分布
Amelie Bonnet-Garnier,Katia Ancelin
Amelie Bonnet-Garnier
Spatial genome organization refers to the conformation of the chromosomes and their relative positioning within the nucleus. In mammals, fertilization entails intense chromatin remodeling of parental genomes, as well as large-scale structur...
REPRODUCTIVE HEALTH IN TRANS AND GENDER-DIVERSE PATIENTS: Trauma-informed reproductive care for transgender and nonbinary people [0.03%]
基于知情同意的跨性别及性别少数群体患者的生育健康护理
Daphna Stroumsa,Nicholas S Raja,Colin B Russell
Daphna Stroumsa
In brief: There are some unique aspects to providing trauma-informed reproductive care to transgender and nonbinary people, who are affected by minority stress, stigma, and particular forms of trauma; we review the eviden...
MiRNA novel-216 regulated fatty acid composition and progesterone synthesis in goat granulosa cells by targeting TPD52 [0.03%]
miRNA新型216通过靶向TPD52调节山羊颗粒细胞脂肪酸组成和孕酮合成
Yuhang Jia,Qiao Xu,Peng Wang et al.
Yuhang Jia et al.
Granulosa cells in the ovaries of livestock are crucial for secreting steroid hormones that regulate follicular development, with lipid synthesis and metabolism playing key roles in this process. The molecular mechanisms behind steroid horm...
Genna E Moldovan,Noura Massri,Erin L Vegter et al.
Genna E Moldovan et al.
In brief: The HIPPO signaling effectors YAP1 and WWTR1 are required for murine pregnancy initiation, and mutation of these factors compromises the decidualization response and overall pregnancy success. ...
IMPACT OF REAL-LIFE ENVIRONMENTAL EXPOSURES ON REPRODUCTION: Phthalate exposure and reproductive effects in rodents: a model for approaches on the protective role of natural products [0.03%]
环境暴露对生殖的影响:邻苯二甲酸盐暴露及啮齿动物的生殖效应:天然产物保护作用的研究模型
Wellerson Rodrigo Scarano,Marina Trevizan Guerra,Juliana Elaine Perobelli et al.
Wellerson Rodrigo Scarano et al.
In brief: Exposure to phthalates, alone or in mixtures, at different periods of development alters the reproductive function of males and females, especially in rodents, where they have been most studied. This review addr...
Decreased miR-486-5p is involved in lipopolysaccharide-induced HTR-8/SVneo cell dysfunction by promoting SMAD2 expression [0.03%]
miR-486-5p下调通过促进SMAD2表达参与脂多糖所致HTR-8/SVneo细胞功能障碍
Yan Gu,Ling-Han Chen,Long Yang et al.
Yan Gu et al.
In brief: Insufficiency of extravillous trophoblast (EVT) cell invasion is implicated in pregnancy complications. This study reveals the roles of the miR-486-5p/Smad2 pathway in lipopolysaccharide (LPS)-induced EVT dysfun...