Obesity-derived metabolites modulate anti-tumor immunity in the tumor microenvironment: from mechanisms to clinical applications [0.03%]
肥胖相关代谢物通过调控肿瘤微环境中的抗肿瘤免疫应答抑制肿瘤免疫治疗效力：从机制到临床转化
Yihang Cai,Junyi Jin,Yihui Wang et al.
Yihang Cai et al.
The tumor microenvironment (TME) is increasingly understood as a metabolically dynamic ecosystem in which local metabolite availability, composition, and trafficking shape immune cell fitness and therapeutic responsiveness. Against the back...
Maternal B-vitamin status modifies the risk of congenital heart disease in offspring associated with prenatal persistent organic pollutants exposure [0.03%]
孕期母体B族维生素状态影响持久性有机污染物致后代先天性心脏病风险
Sainan Li,Hai Lin,Chengrong Wang et al.
Sainan Li et al.
Background: No epidemiological studies have systematically evaluated the associations between prenatal exposure to organophosphate esters and polychlorinated biphenyls and the risk of congenital heart disease (CHD) in off...
Nourishing future generations: the critical role of healthy school lunches and strategic food procurement [0.03%]
培育未来世代：健康学校午餐与战略性食品采购的重要作用
Aurora Perez-Cornago,Carmen Piernas
Aurora Perez-Cornago
Impact of a real-time automatic quality control system for magnetically controlled capsule gastroscopy: a multicenter randomized controlled trial [0.03%]
磁控胶囊胃镜智能质控系统多中心随机对照研究的影响评价
Xiaoya Wang,Dawei Shen,Yusha Zhao et al.
Xiaoya Wang et al.
Background: Quality control can reduce variations in operators' performance conducting magnetically controlled capsule gastroscopy (MCCG). However, an optimal method for quality control in routine MCCG procedures is still...
Medicine price and affordability in China and selected ASEAN countries: a cross-country comparison with forward-looking implications for regional pooled procurement [0.03%]
中国与部分东盟国家的药品价格及可负担性：区域内联合采购的前景展望及其国际比较研究
Zhuangqi Li,Shuting Zhang,Qian Xu et al.
Zhuangqi Li et al.
Background: The China-ASEAN regional medical procurement platform was launched in early 2025. However, the scope and operational mechanisms of the platform remain unclear. This study aims to assess medicine prices and aff...
Long Zhang,Xu Liu,Fangfang Fan et al.
Long Zhang et al.
Background: Dyslipidemia remains a major modifiable contributor to China's cardiovascular disease (CVD) burden, yet large-scale evidence on risk-stratified management gaps is lacking. ...
The neuroimmune axis in breast cancer: from mechanistic insights to clinical applications [0.03%]
乳腺癌中的神免疫经轴：从机制见解到临床应用
Yimao Wu,Kaiyu Zhang,Xinya Xia et al.
Yimao Wu et al.
Background: Breast cancer is the most commonly diagnosed malignancy in women worldwide, and its marked heterogeneity together with the complexity of the tumor microenvironment contributes to substantial variability in the...
Rational use of expensive medicines in the Netherlands: strategies to improve effectiveness and reduce burden on patients and society - a narrative review [0.03%]
荷兰昂贵药物的合理使用：改善疗效并减轻患者和社会负担的策略——叙述性综述
Bart M F Penninx,Sander W Tas,Lonneke Timmers et al.
Bart M F Penninx et al.
Background: While new expensive medicines often offer substantial benefits to patients, they can carry inherent drawbacks such as uncertainty regarding efficacy translating into effectiveness, safety and rational use, as ...
Efficacy and safety of cyclosporine plus luspatercept versus cyclosporine in newly diagnosed non-transfusion-dependent non-severe aplastic anemia: A prospective randomized trial [0.03%]
环孢素联合lusitercept与单用环孢素治疗新诊断的非输血依赖性非重型再生障碍性贫血的疗效及安全性：一项前瞻性随机试验
Zhuxin Zhang,Qinglin Hu,Leyu Wang et al.
Zhuxin Zhang et al.
Background: The clinical need for treating anemia in aplastic anemia (AA) patients remains unmet. Luspatercept has been shown to be effective in myelodysplastic neoplasms (MDS). ...
Adherence to the EAT-Lancet Diet, plasma proteomics, and risk of venous thromboembolism: a large-scale prospective cohort study [0.03%]
遵循EAT-Lancet饮食、血浆蛋白质组与静脉血栓栓塞风险的关系：一项大规模前瞻性队列研究
Qida He,Mengtong Sun,Yu Wang et al.
Qida He et al.
Background: The EAT Lancet diet is increasingly recognized for its simultaneous benefits to human and planetary health. Its key components are known to exert anti-inflammatory and antiplatelet effects; however, the potent...