The gender pain gap in prehospital analgesia: the role of patient and provider gender - an analysis of 106,888 helicopter emergency medical service (HEMS) missions [0.03%]
院前镇痛的性别疼痛差距：患者和提供者性别所起的作用——对106,888例直升机紧急医疗救助任务的分析
Andrea Schmidt,Hans-Jörg Busch,Lilith Huebsch et al.
Andrea Schmidt et al.
Background: Pain management is a core ethical principle in emergency medicine, yet gender-related differences in analgesic treatment have been reported. This study examines whether patient and emergency physician gender i...
Observational Study
BMC medicine. 2026 Aug 6;24(1):426. DOI:10.1186/s12916-026-05131-0 2026
Assessment of Trophoblast cell surface antigen 2 (Trop-2) expression and its clinical significance in breast cancer: a multi-level analysis of protein and gene expression [0.03%]
胎盘滋养层细胞表面抗原2(Trop-2)在乳腺癌中的表达及临床意义的多维度分析：蛋白质水平和mRNA水平联合检测
Maria Angeliki Toli,Michail Sarafidis,Panagiotis Filis et al.
Maria Angeliki Toli et al.
Background: Trophoblast cell surface antigen 2 (Trop-2) is a targetable transmembrane glycoprotein commonly overexpressed in breast cancer (BC). This study combines a systematic review and meta-analysis with a retrospecti...
Meta-Analysis
BMC medicine. 2026 Jul 31;24(1):422. DOI:10.1186/s12916-026-05093-3 2026
The tumour microenvironment influences long-term tamoxifen benefit in postmenopausal ER+/HER2- breast cancer patients: a secondary analysis of the randomised Stockholm Tamoxifen (STO-3) trial [0.03%]
肿瘤微环境影响绝经后ER+/HER2-乳腺癌患者长期接受他莫昔芬治疗的获益：随机Stockholm Tamoxifen（STO-3）试验的事后分析
Paula Camargo-Romera,Miguel Castresana-Aguirre,Oscar Danielsson et al.
Paula Camargo-Romera et al.
Background: The tumour microenvironment (TME) influences breast cancer progression and treatment response. We investigated whether TME composition predicts tamoxifen benefit in postmenopausal women with oestrogen receptor...
Randomized Controlled Trial
BMC medicine. 2026 Aug 5;24(1):424. DOI:10.1186/s12916-026-05091-5 2026
Socioeconomic inequality in recommended childhood vaccinations in Germany: evidence from insurance claims and concentration index decomposition [0.03%]
德国儿童接种疫苗的社会经济差异：来自保险理赔和集中指数分解的证据
Christopher Nussbaum,Leonie Sundmacher,Wiebke Schuettig
Christopher Nussbaum
Background: Despite well-established childhood immunization programs in many high-income countries, vaccination series are often delayed or not completed. Gaps in vaccination coverage are more common among children from s...
Artificial intelligence empowers full-stack histopathological diagnosis and prognosis of renal cell tumor: a multi-center study with external validation [0.03%]
人工智能赋能全流程肾脏细胞肿瘤病理诊断与预后判读：多中心研究及其外部验证
Ying Xiong,Wei Xi,Gelei Zhang et al.
Ying Xiong et al.
Background: The rapid advancement of digital pathology has opened unprecedented opportunities for intelligent diagnosis in renal cell tumor. However, there remains a significant gap in the availability of reliable deep le...
Multicenter Study
BMC medicine. 2026 Aug 4;24(1):408. DOI:10.1186/s12916-026-05110-5 2026
Digital patient safety interventions in primary care: a systematic review and meta-analysis [0.03%]
数字患者安全干预在初级保健中的应用：系统回顾和荟萃分析
Jung Yin Tsang,Claire Planner,Chloe-Nicole Low et al.
Jung Yin Tsang et al.
Background: Patient safety events are among the top ten causes of death and disability worldwide, with most considered preventable, particularly in primary care. Digital interventions are increasingly used in primary care...
Meta-Analysis
BMC medicine. 2026 Aug 3;24(1):407. DOI:10.1186/s12916-026-05048-8 2026
Identification of acute kidney injury in African children hospitalized with malaria: a multinational individual participant data meta-analysis [0.03%]
一项多国个体患者资料的荟萃分析：识别住院治疗疟疾的非洲儿童急性肾损伤状况
Caitlin Bond,Anthony Batte,Folake Afolayan et al.
Caitlin Bond et al.
Background: Historically, acute kidney injury (AKI) has been an underappreciated complication in children with severe malaria. We conducted an individual patient data meta-analysis to model the impact of AKI and its compl...
Genomic and lipidomic analysis reveals lipid mediation of genetic risk in gestational diabetes [0.03%]
基因组和脂质组分析揭示了妊娠期糖尿病中遗传风险的脂质介导机制
Yao Dong,An-Qun Hu,Bai-Xue Han et al.
Yao Dong et al.
Background: Gestational diabetes mellitus (GDM) is a complex metabolic disorder with a substantial genetic component; however, whether lipid species mediate the impact of genetic susceptibility on GDM risk remains unclear...
Impact of COVID-19 pandemic on childhood immunization coverage in Indonesia: lesson learned from a nationwide analysis of the Expanded Programme on Immunization [0.03%]
印度尼西亚儿童免疫接种情况受到新冠肺炎疫情影响分析：来自全国范围扩大免疫规划的数据教训
Amalia Nurina,Evelyn Puspaningrum,Gertrudis Tandy et al.
Amalia Nurina et al.
Background: The COVID-19 pandemic disrupted childhood immunization programmes in many countries worldwide. However, evidence on its impact in low and middle-income countries remains limited. This study examined the impact...
Circulating metabolomic signatures of ultra-processed and minimally processed food intake and risk of cardiovascular disease and type 2 diabetes: 20-year follow-up in the Whitehall II cohort [0.03%]
经过20年随访的Whitehall II队列中，摄入高加工和低度加工食品循环代谢标志物与心血管疾病和2型糖尿病风险的关系
Mengmei E Wang,Annie Britton,Michail Katsoulis et al.
Mengmei E Wang et al.
Background: Higher intakes of ultra-processed food (UPF) and minimally processed food (MPF) are linked to increased and decreased cardiometabolic risks, respectively, though mechanisms underlying these associations remain...