The evolution of the immune system of bees is defined by conservation, expansions, and losses [0.03%]
恒定、扩张和丢失定义了蜜蜂免疫系统的进化路程
Hongfei Xu,Ina Köhler,Thomas J Colgan
Hongfei Xu
Background: Insect pollinators, such as bees, provide essential ecosystem services yet face increasing environmental challenges, including pathogens, which can negatively impact host fitness. Central to host defences are ...
Extraordinary diversity of antiviral immune-related gene families across 38 bat species [0.03%]
来自38种蝙蝠物种的多种抗病毒免疫相关基因家族
Guangshuai Liu,Yingying Ren,Shengyang Zhou et al.
Guangshuai Liu et al.
Background: Despite harboring diverse pathogenic viruses, bats rarely exhibit clinical symptoms of the diseases. Previous research has reported evolutionary characteristics in key antiviral gene families in bats, such as ...
Modeling age-related methylation changes in vitro with intestinal organoids [0.03%]
体外肠道类器官模型模拟年龄相关的甲基化变化
Himani Vaidya,Gennaro Calendo,Kelsey Keith et al.
Himani Vaidya et al.
Background: Intestinal organoids, three-dimensional cultures derived from intestinal stem cells, serve as a promising model for studying aging. DNA methylation is recognized as a biological clock of aging, and we hypothes...
Whole genomes reveal subpopulations and isolation-by-distance patterns in the Norwegian lemming [0.03%]
全基因组揭示挪威北极鼠的亚种群及隔离-by-距离模式
Isabelle Sofie Feinauer,Francesco Ravasini,Vendela Kempe Lagerholm et al.
Isabelle Sofie Feinauer et al.
Background: The Norwegian lemming (Lemmus lemmus) is a small rodent endemic to the Fennoscandian alpine and arctic tundra. The species is known for cyclic population outbreaks and mass movements during peak years. Previou...
The genome of the relict earless monitor lizard, Lanthanotus borneensis, and the Toxicofera hypothesis [0.03%]
无耳 Monitor蜥蜴(Lanthanotus borneensis)基因组与Toxicofera假说
Magnus Wolf,Axel Janke,Krister T Smith
Magnus Wolf
Background: The earless monitor lizard, Lanthanotus borneensis, is a unique living fossil restricted to the island of Borneo and a possible key to understanding the evolution of the venom delivery system and secondary ada...
Different modality-specific mechanisms mediate serial dependence effects in visual and auditory perception [0.03%]
不同的模态特异性机制介导视觉和听觉感知中的序列依赖效应
Irene Togoli,Michele Fornaciai,Domenica Bueti
Irene Togoli
Background: Perceptual history plays an important role in sensory processing and decision making, shaping how we perceive and judge external objects and events. Indeed, past stimuli can bias what we are currently seeing i...
Male sterility in Drosophila hybrids revealed by a multi-generational transcriptomic analysis of genes and transposable elements in testes [0.03%]
雄性杂交果蝇不育性的产生源于生殖细胞系中基因和转座子的表达变化
Alejandra Bodelón,Vicente Chillida,Daniel Siqueira de Oliveira et al.
Alejandra Bodelón et al.
Background: Hybridization can trigger phenotypic and transcriptomic changes, leading to reproductive isolation and genome evolution. Drosophila is a key model for understanding the genetic basis of speciation, yet the com...
An integrative defense mechanism mediated by GhBsr-d1L7 and GhERD10 confers resistance to Verticillium dahliae in cotton [0.03%]
棉花GhBsr-d1L7和GhERD10整合防卫机制赋予其对大丽轮枝菌的抗性
Guoshuai Zhang,Chuanzong Li,Youzhong Li et al.
Guoshuai Zhang et al.
Background: Verticillium wilt (VW), a devastating disease caused by the soil-inhabiting fungus Verticillium dahliae, poses a substantial threat to cotton cultivation worldwide by drastically impairing both yield and fiber...
Stage-specific impacts of a simulated natural heatwave on Aedes albopictus [0.03%]
模拟自然热浪对不同发育阶段的白纹伊蚊的影响
Claudia Alfaro,Alejandro Nabor Lozada-Chávez,Ayda Khorramnejad et al.
Claudia Alfaro et al.
Background: The increase in the frequency and intensity of heatwaves (HWs) under global warming is expected to have more dramatic biological impacts on insects than mean temperature increases. However, evidence of the imp...
BiToxNet: a deep learning framework integrating multimodal features for accurate identification of neurotoxic peptides and proteins [0.03%]
基于深度学习的多模态特征整合框架用于神经毒性肽和蛋白质的精准识别
Feng Wang,Peilin Xie,Xingqiao Lin et al.
Feng Wang et al.
Background: Accurate prediction of the neurotoxicity of peptides and proteins is critically important for the safety assessment of protein therapeutics and the development of protein-based drugs. Although experimental met...