Chemical composition of essential oil of Ferulago macrocarpa (Fenzl) Boiss. fruits [0.03%]
Ferulago macrocarpa (Fenzl) Boiss.果实挥发油的化学成分
S E Sajjadi,Y Shokoohinia,M Jamali
S E Sajjadi
Water-distilled essential oil of Ferulago macrocarpa (Umbelliferae) fruits was analyzed using GC-MS for the first time. Forty-two components comprising 99.5% of the total oil were identified, of which bornyl acetate (40.8%), 2,3,6-trimethyl...
Genotoxic effects of some l-[(benzofuran-2-yl)-phenylmethyl]-imidazoles on MCF-7 cell line [0.03%]
几种L-[(苯并呋喃-2-基)- phenylmethyl] - 咪唑的致突变作用对MCF-7细胞系的影响
M Etebari,G A Khodarahmi,A Jafarian-Dehkordi et al.
M Etebari et al.
Increased exposure to estrogen has been associated with the risk of breast cancer. Substituted benzofuran derivatives with inhibitory effects on estrogen synthesis could be considered as a potential approach to reduce the risk of breast can...
Terminalia arjuna's antioxidant effect in isolated perfused kidney [0.03%]
Terminalia arjuna的抗氧化作用在孤立灌流肾脏中的研究
C David Raj,M Mohamed Shabi,J Jipnomon et al.
C David Raj et al.
Standardization of induction of oxidative stress with Fenton mixture (FM) in isolated perfused rat kidney and the antioxidant effect of Terminalia arjuna bark in the isolated oxidatively stressed rat kidney has been evaluated. Six groups ea...
Synthesis and antioxidant evaluation of some novel ortho-hydroxypyridine-4-one iron chelators [0.03%]
一些新型邻羟基吡啶并酮铁螯合剂的合成及抗氧化评价
M Mohammadpour,A Sadeghi,A Fassihi et al.
M Mohammadpour et al.
A series of ortho-hydroxypyridine-4-ones were prepared in high yields and evaluated for antioxidant and iron chelating activities. N(1)-H hydroxypyridinones Va, Vb, and Ve were the best radical scavengers in DPPH free radical scavenging ass...
Validation and optimization of experimental colitis induction in rats using 2, 4, 6-trinitrobenzene sulfonic acid [0.03%]
2,4,6-三硝基苯磺酸诱导大鼠结肠炎实验的验证与优化研究
A Motavallian-Naeini,S Andalib,M Rabbani et al.
A Motavallian-Naeini et al.
Trinitrobenzene sulfonic acid (TNBS)-induced colitis is one of the most common methods for studying inflammatory bowel disease in animal models. Several factors may, however, affect its reproducibility, rate of animal mortality, and macrosc...
Antibacterial, antifungal and cytotoxic evaluation of some new 2,3-disubstituted 4(3H)-quinazolinone derivatives [0.03%]
一些新的2,3-位取代的4（3H）-喹唑啉酮衍生物的抗菌，抗真菌和细胞毒性评价
G A Khodarahmi,M Rahmani Khajouei,G H Hakimelahi et al.
G A Khodarahmi et al.
In this study antibacterial, antifungal and cytotoxic effects of some new 2,3-disubstituted 4(3H)-quinazolinone derivatives have been evaluated. The in vitro antibacterial and antifungal tests of new synthesized compounds were performed usi...
Antispasmodic effect of osthole and Prangos ferulacea extract on rat uterus smooth muscle motility [0.03%]
欧念珠菌和柴胡素对大鼠子宫平滑肌运动的抗痉挛作用研究
H Sadraei,Y Shokoohinia,S E Sajjadi et al.
H Sadraei et al.
Several species of Prangos are traditionally used as emollient, carminative, tonic, anti-flatulent, anthelmintic and anti-thrombotic agents. Osthole, a coumarin isolated from Prangos, are believed to be responsible for some of its effects. ...
Assessment of selective toxicity of insect cell expressed recombinant A1-GMCSF protein toward GMCSF receptor bearing tumor cells [0.03%]
昆虫细胞表达的重组A1-GMCSF蛋白对GMCSF受体阳性肿瘤细胞的选择性毒性评估
A Jahanian-Najafabadi,S Bouzari,M Oloomi et al.
A Jahanian-Najafabadi et al.
One of the emerging therapeutic strategies for targeted treatment of most cancers is the use of immunotoxins which are fusion proteins consisted of a targeting and a toxic moieties. We previously showed that the recombinant A254-GMCSF fusio...
Effects of the Persian Carum copticum fruit extracts on morphine withdrawal syndrome in mice [0.03%]
库拉索开心果提取物对小鼠吗啡戒断综合征的影响
A Ghannadi,V Hajhashemi,R Abrishami
A Ghannadi
Carum copticum from Apiaceae family has several biological effects including analgesic, anti-inflammatory, anxiolytic and antispasmodic activities. This study was designed to evaluate its effect on suppression of naloxone-induced morphine w...
Synthesis and cytotoxic evaluation of some new 4(3H)-quinazolinones on HeLa cell line [0.03%]
几种新的4(3H)喹唑啉酮的合成及其对HeLa细胞系的细胞毒性评价
G A Khodarahmi,M Shamshiri,F Hassanzadeh
G A Khodarahmi
Quinazolinone backbone is present in a large number of bioactive substances. Since remarkable cytotoxic activity is associated with some 4(3H)-quinazolinones, in this study some 4(3H)-quinazolinone were synthesized and screened against HeLa...