BATF Drives Cervical Cancer Progression and Immune Evasion by Regulating the STAT1-PD-L1 Axis [0.03%]
BATF通过调节STAT1-PD-L1轴驱动宫颈癌进展和免疫逃逸
Jun Zhang,Yang Zhang,Jinwei Zhang
Jun Zhang
Background: Cervical cancer progression is driven by immune evasion mechanisms, including PD-L1-mediated suppression of T cell activity. BATF, a transcription factor, has been linked to tumor immunity; cancer remains inco...
Antitumor Effects of Tumor-Derived Exosomes in Murine Hepatocellular Carcinoma Models [0.03%]
肿瘤来源外泌体的抗肿瘤效果及机制研究小鼠肝癌模型
Weibing Xu,Lulu Fan
Weibing Xu
Background: Exosomes (EXOs) are small vesicles derived from endosomes and secreted by most living cells including tumor cells. In recent years, these vesicles have been recognized as key mediators of intercellular communi...
In Vitro Expansion of Dendritic Cells Pulsed with Placental Peptides for the Generation of Antigen-Specific T Cells with Antitumor Activity [0.03%]
负载胎盘多肽的树突状细胞体外扩增诱导抗肿瘤特异性T细胞的效果研究
Yu Lin,NengPing Huang,YuanBin He et al.
Yu Lin et al.
Background: Placental tissue contains a variety of tumor-associated antigens. Antigen-specific T cells generated by expanded dendritic cells (DCs) loaded with placental peptides have the potential to exert antitumor effec...
Differential Functions of Membrane-bound and Soluble TNF-α in Regulating Trophoblasts Invasion and Migration [0.03%]
膜型和可溶型TNF-α调节滋养细胞侵袭迁移的功能差异研究
Chenxi Li,Mingxin Lin,Min Zhu et al.
Chenxi Li et al.
Background: Proper invasion and migration of trophoblasts are critical for successful human pregnancy. Tumor necrosis factor-α (TNF-α) has two biologically active forms: the membrane-bound TNF-α (mTNF) and the soluble ...
Expression and Prognostic Significance of PD-1/PD-Ls in Breast Cancer Draining Lymph Nodes [0.03%]
乳腺癌引流淋巴结中PD-1/PD-Ls的表达及其预后意义
Zahra Mansourabadi,Ali Moazzeni,Majid Akrami et al.
Zahra Mansourabadi et al.
Background: Tumor-draining lymph nodes play a pivotal role in orchestrating immune cell trafficking and initiating antitumor responses. Among immunoregulatory molecules, programmed cell death protein 1 (PD-1) has emerged ...
Diagnostic Utility of Anti-Cyclic Citrullinated Peptide Antibodies Versus Rheumatoid Factor in Libyan Patients with Rheumatoid Arthritis: A Cross-Sectional Study [0.03%]
利比亚类风湿性关节炎患者的抗环瓜氨酸肽抗体与类风湿因子诊断效用的横断面研究
Eida Elmansorry
Eida Elmansorry
Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation and progressive destruction of joint structures. Anti-cyclic citrullinated peptide (anti-CCP) antibodies have em...
Comparative Study
Iranian journal of immunology : IJI. 2025 Dec 10;22(4). DOI:10.22034/iji.2025.108275.3090 2025
The Immunoregulatory Role of Programmed Death-Ligand 1 in Wound Healing Dynamics [0.03%]
程序性死亡配体1在伤口愈合过程中的免疫调节作用
Mohammad Hasan Soheilifar,Hoda Keshmiri Neghab,Sima Nobari
Mohammad Hasan Soheilifar
Wound healing is a complex and dynamic process that encompasses four interrelated phases: hemostasis, inflammation, proliferation, and remodeling. Inflammation plays a pivotal role in both acute and chronic wound healing. In chronic diabeti...
Advances in Understanding Immune Dysregulation and Therapeutic Strategies Targeting Epidermal and Dermal Cells in Keloids [0.03%]
瘢痕疙瘩中表皮和真皮细胞免疫异常研究进展及其治疗策略
Yuan Xia,Jing Niu,Hengheng Fan et al.
Yuan Xia et al.
Keloid, as a skin fibrotic proliferative disorder, have a complex pathogenesis that remains incompletely understood. It is characterized by abnormal and excessive scar formation following skin injury. The occurrence and development of keloi...
Next-generation Pertussis Vaccines with Special Focus on Intranasal Vaccination [0.03%]
新一代百日咳疫苗（特别是鼻内接种）的专题讨论会
Yahya Ehteshaminia,Forough Golsaz-Shirazi,Mohammad Mehdi Amiri et al.
Yahya Ehteshaminia et al.
Pertussis is a highly contagious respiratory disease caused by the gram-negative bacterium Bordetella pertussis (Bp). The disease is most severe in infants and young children, whereas adolescents and adults typically experience milder sympt...
Therapeutic Potential of an Anti-PLAC1 Antibody-Drug Conjugate in a Mouse Model of Human Breast Cancer [0.03%]
一种抗PLAC1抗体偶联药物治疗人类乳腺癌小鼠模型的潜力
Jafar Mahmoudian,Roya Ghods,Mahmood Jeddi-Tehrani et al.
Jafar Mahmoudian et al.