Beyond biochemistry: multiparametric ultrasound parameters and their molecular correlates in cardio-renal-metabolic syndrome [0.03%]
超越生化：心血管代谢综合征的多参数超声及其分子标志物关联性研究
Marcin L Kutek,Jacek M Witkowski
Marcin L Kutek
Cardio-renal-metabolic syndrome (CRMS)-characterized by the pathological interplay of visceral adiposity, insulin resistance, chronic kidney disease, and cardiovascular disease-affects over 90% of US adults across its staging spectrum, yet ...
Divergence in surface protein exposure between reference and clinical-derived Candida glabrata (Nakaseomyces glabratus) strains (CBS138 vs. BG2) - a preliminary proteomic perspective [0.03%]
参考和临床分离的荚膜平滑酵母(CBS138与BG2)菌株间表面蛋白暴露差异-初步蛋白质组学视角
Aneta Bednarek,Olga Barczyk-Woznicka,Justyna Karkowska-Kuleta et al.
Aneta Bednarek et al.
Candida glabrata (currently classified as Nakaseomyces glabratus) is an opportunistic fungal pathogen notable for its intrinsic antifungal tolerance and ability to persist in host environments. Although strain CBS138 has served as the princ...
Mitochondrial morphology and mtDNA content in fibroblasts from patients with different types of mucopolysaccharidosis [0.03%]
不同类型的黏多糖贮积症患者的成纤维细胞中的线粒体形态和mtDNA含量差异
Klaudia Walczak,Lidia Gaffke,Karolina Pierzynowska et al.
Klaudia Walczak et al.
Mucopolysaccharidosis (MPS) is a group of inherited metabolic diseases, characterized by defects in the degradation of glycosaminoglycans and their accumulation in lysosomes. However, various secondary cellular changes also contribute to th...
Kyna Rigouts,Gregor Becker
Kyna Rigouts
Mirror bacteria are organisms constructed from mirror-image biomolecules unlike those used by all known life and are moving from theoretical concept to practical feasibility. Their unusual chemistry that makes them resistant to natural degr...
Elemental changes in tooth hard tissues during demineralization and fluoride-induced remineralization: an SEM-EDX study [0.03%]
扫描电镜能谱分析牙齿硬组织脱矿和加氟再矿化过程中元素的变化
Svanishvili Nino,Mamaladze Marina,Mauro Labanca et al.
Svanishvili Nino et al.
Background: Tooth enamel and dentin are the most highly mineralized tissues in the human body, and their structural stability depends on the balanced content of calcium (Ca), phosphorus (P), and fluoride (F). Demineraliza...
Precise genome modification of agrobacterium based on one-step homologous recombination via endogenous transfer DNA [0.03%]
基于内源转移DNA的农杆菌同源重组一步法基因组精炼组装技术
Yu Liu,Geng Sun,Chunyan Gao et al.
Yu Liu et al.
Here, a simple and precise genome modification method for agrobacterium was described and tested in strain GV3101. Taking the induced endogenous Transfer DNA (T-DNA) as the single-strand homologous repair template, this makes it possible to...
Recommendations of the Polish Zebrafish Society on the use of the zebrafish (Danio rerio) model in biomedical research [0.03%]
波兰斑马鱼学会关于在生物医学研究中使用斑马鱼（丹尼洛氏鲤）模型的建议
Piotr Podlasz,Marta Migocka-Patrzałek,Tomasz K Prajsnar et al.
Piotr Podlasz et al.
The zebrafish (Danio rerio) has become a widely adopted vertebrate model in biomedical research, offering high translational value while supporting the principles of Replacement, Reduction, and Refinement (3Rs). Here, the Polish Zebrafish S...
Pilot analysis of protein profile alterations in plasma and aortic tissue of spontaneously hypertensive rats [0.03%]
自发性高血压大鼠血浆和主动脉组织蛋白组改变的初步分析
Anastasios Papageorgiou,Fragkiski-Ioanna Sofiou,Anastassios Philippou et al.
Anastasios Papageorgiou et al.
The role of proteins in cellular activity has received close attention. Proteome analysis can detect early enough changes in the cell before the appearance of pathological changes. Due to the increasing number of cardiovascular complication...
Joanna Igielska-Kalwat
Joanna Igielska-Kalwat
Extreme indoor and outdoor conditions in patients' places of stay (hot or cold air and changes in humidity) lead to weakening of the lipid barrier function and disproportionate epidermal microbiota which results in a lower threshold of phys...
Genetic architecture of obesity and advances in precision pharmacotherapy: a comprehensive review [0.03%]
肥胖的遗传结构及精确诊断药物治疗的最新进展：全面综述
Floren Kavaja,Thomas Liehr,Gazmend Temaj
Floren Kavaja
Obesity, a global health catastrophe, arises from complex interactions between environmental factors and genetic predispositions. This review summarizes the current state of knowledge on the genetic basis of obesity and contrasts rare monog...