Species barriers in AAV tropism: mechanisms, models, and emerging solutions for clinical translation [0.03%]
Xinyuan Xu
Xinyuan Xu
Adeno-associated virus (AAV) vectors have become central to in vivo gene therapy across genetic and acquired diseases. Yet despite extensive preclinical validation, AAV programs often encounter translational gaps when advancing from rodents...
Association between systemic inflammatory markers and recurrence risk in benign paroxysmal positional vertigo: a retrospective cohort study [0.03%]
Bekir Doğan,Deniz Baklacı
Bekir Doğan
Objective: Benign paroxysmal positional vertigo (BPPV) is a common vestibular disorder that responds well to canalith repositioning maneuvers but is frequently complicated by recurrence. Increasing evidence suggests that ...
Differential in vitro and in vivo responses of Akkermansia muciniphila to Odontosoria biflora (Kaulf.) C.Chr. [ Lindsaeaceae] hexane extract in diet- and alloxan-induced BALB/c mice [0.03%]
Akkermansia muciniphila对Odontosoria biflora六氯化物提取物的体外和体内差异响应：饮食诱导及alloxan诱导BALB/c小鼠模型中的作用
Marvie Hamel Darbandi,Leslie Michelle M Dalmacio
Marvie Hamel Darbandi
Akkermansia muciniphila is a mucin-degrading gut bacterium linked to metabolic health, yet culture-based growth stimulation may not translate to sustained enrichment in vivo. Odontosoria biflora ("tubho") is traditionally consumed in the Ph...
Structural potential of the 5' noncoding regions of the mRNAs encoding p53 isoforms [0.03%]
p53异构体编码mRNA的5'-非编码区结构潜能分析
Mariola Dutkiewicz,Paulina Zydowicz-Machtel
Mariola Dutkiewicz
Famous for its nickname "guardian of the genome," the p53 protein acts, among other things, as a transcription factor in the form of a tetramer, which may consist of different types of p53 isoforms. They differ in length and content of spec...
Bibliometric analysis of research trends on the epiretinal membrane since 2000 [0.03%]
2000年以来视网膜前膜研究趋势的文献计量分析
ShuHan Zeng,Rui Wang,Jie Chen et al.
ShuHan Zeng et al.
Epiretinal membrane (ERM) is an important retinal disorder, yet its global research landscape has not been systematically evaluated. This study conducted a comprehensive bibliometric analysis of ERM-related publications indexed in the Web o...
Milena Cichon,Alicja Jozkowicz,Anna Grochot-Przeczek
Milena Cichon
Adeno-associated virus (AAV) vectors have become a cornerstone of in vivo gene delivery. However, although the endothelium is the first cellular interface encountered after systemic delivery, native AAV serotypes exhibit poor endothelial tr...
Low calcium intake from diet and supplements in a group of Polish patients with SLE - an additional risk for osteoporotic fractures? [0.03%]
来自一组波兰SLE患者的饮食和补充剂低钙摄入量——骨质疏松性骨折的额外风险因素？
Jolanta Anna Dardzińska,Natalia Matysiak,Karolina Kułakowska et al.
Jolanta Anna Dardzińska et al.
Background: Patients with systemic lupus erythematosus (SLE) are at increased risk of osteoporosis. Despite this, the awareness of adequate dietary calcium intake and other prevention strategies is often underrecognized i...
Vitamin D, calcium, phosphates, and magnesium serum level and bone mineral density in patients with type 1 diabetes [0.03%]
1型糖尿病患者的血清维生素D、钙、磷和镁水平及骨矿密度
Agnieszka Zawada,Michał Michalak,Dariusz Naskręt et al.
Agnieszka Zawada et al.
Introduction: Abnormal glucose metabolism, which is a common condition in patients with type 1 diabetes (T1DM), triggers a number of changes in various organs. Additionally, elevated blood glucose level also affects the b...
The role of serum tryptase in COVID-19 pathogenesis and its value as a prognostic marker: a single-center prospective cohort study [0.03%]
血清肥大细胞趋化蛋白-8作为冠状病毒疾病的血浆生物标志物：病例对照研究及功能分析
Alan Majeranowski,Damian Palus,Michał Hoffmann et al.
Alan Majeranowski et al.
Background: Dysregulated inflammation is central to COVID-19 pathogenesis. Mast cells (MCs) and their protease tryptase are implicated in tissue injury and vascular dysfunction, but the prognostic value of circulating try...
Linlin Zheng,Hui Sun,Ning Li et al.
Linlin Zheng et al.
RNA splicing is a fundamental post-transcriptional mechanism that enables the generation of diverse mRNA isoforms from a single gene, thereby expanding proteomic complexity and regulating cell fate decisions. Emerging evidence highlights th...