Ewa Brzezińska-Błaszczyk,Maciej Wierzbicki
Ewa Brzezińska-Błaszczyk
Taking into account the role of mast cells in different physiological and pathological processes, as well as in host defense it seems very important to recognize mast cell receptors and their role in activation of these cells. In the last f...
Marta Czyzewska,Anna Wolska,Agnieszka Cwiklińska et al.
Marta Czyzewska et al.
Dyslipidemia in metabolic syndrome (MS), called the atherogenic triad, includes elevated levels of plasma triglycerides (TGs), low levels of HDL-cholesterol (HDL-CH), and the presence of small dense low-density lipoproteins (sdLDLs) with no...
[Angiogenesis and immune suppression: yin and yang of tumor progression?] [0.03%]
[血管生成与免疫抑制：肿瘤进展的阴阳关系？]
Stanisław Szala
Stanisław Szala
Specialized variants of neoplastic cells that appear in tumors during cancer disease progression possess the ability to recruit certain kinds of hematopoietic and mesenchymal cells from the bone marrow or bloodstream. These tumor-recruited ...
Zofia Marchewka,Agata Grzebinoga
Zofia Marchewka
Although diabetes mellitus, a metabolic disease, does not fall into the group of diseases induced by toxic substances or environmental pollution, there is much evidence that some chemicals have considerable importance in its development. Ex...
[Genetics of dementias, Part 4: a spectrum of mutations responsible for the familial autosomal dominant form of Alzheimer's disease] [0.03%]
痴呆的遗传学第四部分：早老素1基因突变引起阿尔茨海默病家族性常染色体显形疾病的谱系分布
Anna Kowalska
Anna Kowalska
Fifty years ago it was demonstrated that some patients with Alzheimer's disease (AD) had an autosomal dominant Mendelian pattern of disease inheritance. Familial and early-onset cases (familial Alzheimer's disease, FAD) are rather rare and ...
[The genetics of dementias, Part 3: a molecular basis for the multifactorial inheritance of sporadic Alzheimer's disease] [0.03%]
痴呆的遗传学 第3部分：散发性阿尔茨海默病多因子遗传分子基础
Anna Kowalska
Anna Kowalska
The majority of Alzheimer's disease cases, i.e. more than 85% of the whole population of patients, can be referred to as the sporadic form of the disease, with a negative family history and complex inheritance. As the genetic background of ...
Izabela Dereń-Wagemann,Małgorzata Kuliszkiewicz-Janus,Kazimierz Kuliczkowski
Izabela Dereń-Wagemann
Mastocytosis is a heterogeneous group of rare diseases characterized by the proliferation and accumulation of mast cells in one or more organs such as the skin, bone marrow, liver, spleen, and lymph nodes. According to the WHO classificatio...
[Proteomic analysis of protein profiles in some pathological stages of the human organism] [0.03%]
[人类机体某些病理阶段的蛋白质组分析]
Barbara Kossowska,Ilona Dudka,Roman Gancarz et al.
Barbara Kossowska et al.
Two-dimensional gel electrophoresis (2-DE) is a widely used method for separation of the proteins of a proteome and it enables their detection in a large concentration range. Sample preparation for isoelectric focusing and SDS-PAGE electrop...
[Amphibian skin secretions as a new source of antibiotics and biologically active substances] [0.03%]
[两栖动物皮肤分泌物作为抗生素和生物活性物质的新来源]
Ireneusz Całkosiński,Arkadiusz Zasadowski,Agnieszka Bronowicka-Szydełko et al.
Ireneusz Całkosiński et al.
So far, the main sources of biologically active substances used in medicine have been plants, molds, and propolis. The obtained compounds have either therapeutic features or require additional modification. They are sometimes combined with ...
[The roles of orphan nuclear receptors in T-lymphocyte development in the thymus] [0.03%]
孤儿核受体在胸腺T淋巴细胞发育中的作用
Janusz Matuszyk
Janusz Matuszyk
T-lymphocyte development in the thymus proceeds through successive steps of differentiation,selection and expansion of thymocytes. Multiple signaling proteins and transcription factors play important roles in mediating the response to signa...