Teresa Piskorska,Ewa Obłak
Teresa Piskorska
Gemini surfactants are a new class of amphiphilic compounds built from two classic surfactant moieties bound together by a special spacer group. These compounds appear to be excellent for creating complexes with DNA and are effective in med...
[The role of T-regulatory cells in the pathogenesis of immunological disturbances accompanying obesity and atherosclerosis] [0.03%]
[调节性T细胞在肥胖和动脉粥样硬化免疫紊乱发病机制中的作用]
Włodzimierz Luczyński,Artur Bossowski,Barbara Głowińska-Olszewska et al.
Włodzimierz Luczyński et al.
Obesity and atherosclerosis, and their consequences, including cardiovascular disease, are plagues of the 21st century. Chronic inflammation, whose mechanism is not well understood, underlies the pathophysiological bases of both processes. ...
Maria Magdalena Tomasiak-Łozowska,Anna Bodzenta-Łukaszyk,Marian Tomasiak et al.
Maria Magdalena Tomasiak-Łozowska et al.
Asthma is a chronic inflammatory disorder of the airways in which many cells and cellular elements play roles. Interleukins 5 (IL-5) and 13 (IL-13) are cytokines which play important roles in the pathophysiology of asthma. Selective accumul...
Andrzej Nagalski,Anna Kiersztan
Andrzej Nagalski
Endogenous glucocorticoids (GCs) are secreted into the systemic circulation from the adrenal cortex. This release is under the control of the circadian clock and can be enhanced at any time in response to a stressor. The levels of circulati...
[Anti-inflammatory pro-resolving derivatives of omega-3 and omega-6 polyunsaturated fatty acids] [0.03%]
[抗炎促解决的ω-3和ω-6多元不饱和脂肪酸衍生物]
Jerzy Z Nowak
Jerzy Z Nowak
Inflammation is a physiological defense reaction of living tissues to injury or infection. An array of mediators, including those derived from omega-6 (omega6) polyunsaturated fatty acids (PUFAs), such as arachidonic acid (AA) e.g. prostagl...
[Molecular mechanisms of parthenolide's action: Old drug with a new face] [0.03%]
[白桦酸作用的分子机制研究：老药新用]
Kamila Koprowska,Małgorzata Czyz
Kamila Koprowska
Parthenolide, a sesquiterpene lactone derived from the leaves of feverfew (Tanacetum parthenium), is considered a main bioactive component of this herb. Feverfew has been used orally or as an infusion for the treatment of migraine, arthriti...
[Alterations of Lewis histo-blood group antigen expression in cancer cells] [0.03%]
Lewis血型糖类抗原在肿瘤细胞中的变化规律研究进展
Radosław Kaczmarek
Radosław Kaczmarek
Carcinogenesis in various tissues is accompanied by alterations in protein and lipid glycosylation, such as changes in the expressions of Lewis histo-blood group antigens. Neoplastic transformation is often followed by changes in expression...
[The structure and cellular regulation of p73: their implication in anticancer therapy] [0.03%]
p73的结构及其细胞调控在抗肿瘤治疗中的意义
Joanna Zawacka-Pankau,Katarzyna Maleńczyk,Alicja Sznarkowska
Joanna Zawacka-Pankau
p73 protein belongs, together with p63, to the p53 family. It is a relatively poorly studied structural and functional homolog of the well-described tumor suppressor protein p53, also known as the guardian of the genome. p73 protein, like p...
Lilianna Kulczycka,Anna Woźniacka
Lilianna Kulczycka
Since wellbeing and health have become fashionable and widespread polypragmasia is popular, adverse drug reactions are particularly important medical problem. Pregnant women as well as breast-feeding mothers need very particular care from t...
Małgorzata Zwolińska,Piotr Smolewski
Małgorzata Zwolińska
Onconase (ranpirnase) is a homologous protein obtained from Rana pipiens frog eggs. The activity of onconase, and particularly its antitumor effect, is strictly connected with ribonuclease(RN-ase) activity. Onconase induces cell death throu...