[Anthocyanins as components of functional food for cardiovascular risk prevention] [0.03%]
花青素作为心血管危险因素预防的功能食品成分
Joanna Saluk-Juszczak
Joanna Saluk-Juszczak
Epidemiologic studies suggest that the regular consumption of polyphenols, secondary metabolites of plants, is correlated with a decrease of the risk of cardiovascular disease, diabetes, arthritis and cancer. The most abundant flavonoid con...
[Rosacea] [0.03%]
[ rosacea ]玫瑰痤疮
Ewa Robak,Lilianna Kulczycka
Ewa Robak
Rosacea is a chronic, inflammatory disease of the skin, usually localized on the face. The disease predominantly affects inhabitants of Northern and Western Europe and North America and is rarely found among other ethnic groups. The disease...
[Gene polymorphisms of renin-angiotensin-aldosterone system components and the progression of chronic kidney diseases] [0.03%]
肾素血管紧张素醛固酮系统各成分基因多态性与慢性肾脏病进展的关系研究
Agata Kujawa-Szewieczek,Magdalena Kocierz,Grzegorz Piecha et al.
Agata Kujawa-Szewieczek et al.
The renin-angiotensin-aldosterone system (RAAS) plays an important role in the pathogenesis of hypertension as well as cardiovascular diseases and chronic kidney diseases. Among the most frequently studied RAAS gene polymorphisms are the an...
Paulina Niedźwiedzka-Rystwej,Agata Mękal,Wiesław Deptuła
Paulina Niedźwiedzka-Rystwej
Development of artherosclerosis is associated with participation of various cell types of the immune system such as: granulocytes, B and T lymphocytes, mast cells, dendritic cells and progenitor cells. Cytokines and growth factors have a gr...
[The role of stromal mast cells in the modification of CD4+CD25+Foxp³ regulatory T cells, Th17 lymphocytes and cytotoxic lymphocytes Tc1 in the development and progression of tumor] [0.03%]
肿瘤发生发展中瘤周基质肥大细胞对调节性T细胞、Th17淋巴细胞及CTLs极化的作用及其机制研究
Katarzyna Starska,Ewa Brzezińska-Błaszczyk
Katarzyna Starska
Despite the lack of direct evidence that immune surveillance cells protect against tumor development, indirect clinical observations and experimental studies indicate activity in the immune response against cancer cells of various origin. L...
[Pharmacological activation of tumor suppressor, wild-type p53 as a promising strategy to fight cancer] [0.03%]
[通过药理学方法激活肿瘤抑制基因野生型p53作为抗肿瘤的有前景的策略]
Alicja Sznarkowska,Robert Olszewski,Joanna Zawacka-Pankau
Alicja Sznarkowska
A powerful tumor suppressor--p53 protein is a transcription factor which plays a critical role in eliciting cellular responses to a variety of stress signals, including DNA damage, hypoxia and aberrant proliferative signals, such as oncogen...
Magda Rybicka,Piotr Stalke,Krzysztof Piotr Bielawski et al.
Magda Rybicka et al.
Liver is a key organ responsible for organism’s homeostasis. A proper function of this organ is crucial for detoxification of metabolic products and regulation of metabolic processes of macromolecules (proteins, lipids, carbohydrates). The...
[Mechanisms involved in the regulation of immune response in animal model of rheumatoid arthritis in mice (CIA)] [0.03%]
[利用动物模型（ CIA ）探讨类风湿性关节炎中调控免疫反应的机制]
Katarzyna Marcińska,Marian Szczepanik
Katarzyna Marcińska
Rheumatoid arthritis (RA) represents an example of the autoimmune disease. With a prevalence of 1% worldwide, the pathogenesis of RA is not clear yet. At present it is thought that the pathogenesis of RA results from an inflammatory respons...
[Role of Toll-like receptors in etiology of selected diseases of the skin] [0.03%]
toll样受体在某些皮肤病发病机制中的作用
Lilianna Kulczycka,Anna Sysa-Jędrzejowska,Ewa Robak
Lilianna Kulczycka
Toll-like receptors (TLR) play an important role in anti-infectious defense of organisms. So far in humans 10 receptors have been identified. They were classified into five different subfamilies according to their affinity to characteristic...
Zofia M Kiliańska,Jolanta Zołnierczyk,Józefa Wesierska-Gadek
Zofia M Kiliańska
Poly(ADP-ribose)polymerase-1 (PARP-1) catalyzes the polymerization of ADP-ribose units from NAD+ modules on target proteins, resulting in the attachment of linear or branched polymers. PARP-1 and its product poly(ADP-ribose)--PAR have recen...