Areta Hebanowska
Areta Hebanowska
Bile acid biosynthesis is the main pathway of cholesterol catabolism. Bile acids are more soluble than cholesterol so are easier to excrete. As amphipathic molecules they participate in lipid digestion and absorption in the intestine and th...
[The role of the glutamatergic system in the pathogenesis and treatment of alcohol dependence] [0.03%]
谷氨酸系统在酒精依赖发病机制和治疗中的作用
Karina Łukasik,Karolina Piątkowska,Bogusława Pietrzak
Karina Łukasik
The lack of satisfactory results of alcohol dependence treatment has necessitated the search for new directions of studies. One of them is connected with glutamatergic transmission. The influence of alcohol on this transmission is very comp...
Krzysztof Domagalski,Andrzej Tretyn,Małgorzata Pawłowska et al.
Krzysztof Domagalski et al.
Type III interferons, also known as IFN-lambda or IL-28/29, are a recently discovered family of IFNs related to both the type I IFNs and interleukin-10 family members. Interferon-lambda is functionally an interferon but structurally it is r...
[The role of AMP-activated protein kinase in regulation of skeletal muscle metabolism] [0.03%]
[AMP活化的蛋白激酶调节骨骼肌代谢的作用]
Anna Dziewulska,Paweł Dobrzyń,Agnieszka Dobrzyń
Anna Dziewulska
AMP-activated protein kinase (AMPK) is a conserved, ubiquitously expressed eukaryotic enzyme that is activated in response to increasing AMP level. Regulation of AMPK activity in skeletal muscle is coordinated by contraction and phosphoryla...
[RNA interference as a potential tool for diagnosis and therapy of some human diseases] [0.03%]
RNA干扰作为诊断和治疗某些人类疾病的一种潜在工具
Paweł Jóźwiak,Anna Lipińska
Paweł Jóźwiak
RNA interference is one of the most important discoveries in the field of molecular biology. To date, many studies have been reported which suggest that RNA interference takes part in various biological processes essential for the developme...
[Akt kinase: a key regulator of metabolism and progression of tumors] [0.03%]
[ Akt激酶：一个关键的代谢和肿瘤发展的调节器]
Anna Krześlak
Anna Krześlak
The serine/threonine protein kinase Akt is a major transducer of the phosphoinositide 3-kinase pathway and plays a crucial role in regulation of cellular processes such as growth, metabolism, survival and proliferation. Mammalian cells are ...
Maja Kazubek,Anna Długosz,Krzysztof Pawlik
Maja Kazubek
Molecular biology techniques have become widely used in toxicology, leading to the creation of a new science--molecular toxicology. The goal of molecular toxicology is to detect and study the changes induced by xenobiotics at the molecular ...
Anna Gromotowicz,Urszula Osmólska,Maria Mantur et al.
Anna Gromotowicz et al.
Recent studies have focused on a new wave of interest in aldosterone due mainly to its growing profile as a local messenger in pathology of the cardiovascular system, rather than its hormonal action. In the last few years strong evidence fo...
FLT3 internal tandem duplication and FLT3-D835 mutation in 80 AML patients categorized into cytogenetic risk groups [0.03%]
80例按细胞遗传学危险度分层的急性髓系白血病患者FLT3内部串联重复和FLT3-T835突变检测
Ewa Mały,Marta Przyborsk,Tomasz Nowak et al.
Ewa Mały et al.
Background: Acute myeloid leukemia (AML) is a clonal disorder characterized by various genetic abnormalities and variable response to treatment. About 50% of patients with AML have no cytogenetic aberrations, presenting n...
Clinical Trial
Postepy higieny i medycyny doswiadczalnej (Online). 2010 Oct 18:64:466-70. DOI: 2010
Ewa Obłąk,Anna Krasowska
Ewa Obłąk
Lysosomotropic agents have antitumor, antifungal and antimicrobial properties. These small, amphiphilic compounds, as weak bases, readily penetrate the lipid bilayer and diffuse into acidic subcellular compartments such as lysosomes or vacu...