Piotr Wasąg,Robert Lenartowski
Piotr Wasąg
The nuclear matrix (NM), or nuclear skeleton, is the non-chromatin, ribonucleoproteinaceous framework that is resistant to high ionic strength buffers, nonionic detergents, and nucleolytic enzymes. The NM fulfills a structural role in eukar...
Anti‑cytokine therapy for psoriasis - not only TNF‑α blockers. Overview of reports on the effectiveness of therapy with IL‑12/IL‑23 and T and B lymphocyte inhibitors [0.03%]
抗细胞因子治疗银屑病——不仅限于TNF-α拮抗剂：关于IL-12/IL-23和T/B淋巴细胞抑制剂疗效的文献综述
Dominika Wcisło-Dziadecka,Martyna Zbiciak,Ligia Brzezińska-Wcisło et al.
Dominika Wcisło-Dziadecka et al.
TNF‑α inhibitors - infliximab, etanercept and adalimumab - can be used in the treatment of psoriasis vulgaris and psoriatic arthritis, along with other inhibitors of proinflammatory cytokines, such as interleukin‑12 (IL‑12) and IL‑23. ...
Weronika Lucas Grzelczyk,Janusz Szemraj,Magdalena Józefowicz-Korczyńska
Weronika Lucas Grzelczyk
One of the most common carcinoma occurring in the head and neck is laryngeal cancer. Despite the rapid scientific advances in medicine the prognosis for patients with such type of disease is not satisfying. In the last few years matrix meta...
The role of survivin in the diagnosis and therapy of gynaecological cancers [0.03%]
Survivin在妇科肿瘤诊断和治疗中的作用
Marta Denel-Bobrowska,Agnieszka Marczak
Marta Denel-Bobrowska
Survivin is a member of the family of apoptosis inhibitors. It regulates several essential cellular processes, i.e. it inhibits apoptosis and promotes cell proliferation, DNA repair and autophagy. Survivin is responsible for development of ...
Anna Antonina Sobocińska,Anna M Czarnecka,Cezary Szczylik
Anna Antonina Sobocińska
Mechanism of forming new capillary from basal vessels, named angiogenesis, exist under both physiological and pathological conditions. Initiation of this process requires imbalance between proangiogenic and antiangiogenic factors, which can...
Agata Sarniak,Joanna Lipińska,Karol Tytman et al.
Agata Sarniak et al.
The main cellular source of reactive oxygen species (ROS) is mitochondrial respiratory chain and active NADPH responsible for "respiratory burst" of phagocytes. Whatsmore ROS are produced in endoplasmic reticulum, peroxisomes, with the part...
The role of adipose tissue and excess of fatty acids in the induction of insulin resistance in skeletal muscle [0.03%]
脂肪组织及过量的脂肪酸在骨骼肌胰岛素抵抗诱导中的作用
Agnieszka Błachnio-Zabielska,Sławomir Grycel,Marta Chacińska et al.
Agnieszka Błachnio-Zabielska et al.
Skeletal muscle is the main tissue responsible for insulin-stimulated glucose uptake. Consumption of a high-fat diet rich in saturated fats (HFD) and obesity are associated with accumulation of intramuscular lipids that leads to several dis...
Bartosz Kulczyński,Anna Gramza-Michałowska
Bartosz Kulczyński
Cardiovascular diseases are the leading cause of death worldwide. Literature data indicate that, due to these diseases, approximately 17.5 million people died in 2012. Types of cardiovascular disease include ischemic heart disease, cerebrov...
C-reactive protein as a diagnostic and prognostic factor in inflammatory bowel diseases [0.03%]
C反应蛋白在炎症性肠病中的诊断和预后价值
Dorota Mańkowska-Wierzbicka,Jacek Karczewski,Barbara Poniedziałek et al.
Dorota Mańkowska-Wierzbicka et al.
Aim: The study aimed to evaluate high-sensitivity CRP (hsCRP) as a diagnostic and predictive marker in patients with inflammatory bowel disease (IBD). Mat...
Iga Wierzbicka-Tutka,Grzegorz Sokołowski,Agata Bałdys-Waligórska et al.
Iga Wierzbicka-Tutka et al.
Introduction: Prothymosin alpha (PTMA), a nuclear oncoprotein involved in cell cycle regulation, is used as a prognostic marker in many cancers. The histopathology of pituitary carcinomas and locally invasive adenomas is ...