Prognostic value of thymidine kinase activity in patients with chronic lymphocytic leukemia [0.03%]
胸苷激酶活性在慢性淋巴细胞白血病患者中的预后价值
Piotr Stelmach,Jerzy Z Błoński,Ewa Wawrzyniak et al.
Piotr Stelmach et al.
Thymidine kinase (TK) activity is a marker of biological activity that allows the indolent and aggressive forms of chronic lymphocytic leukemia (CLL) to be distinguished. The aims of the study were to determine the relationship between TK a...
Małgorzata Pokrywka,Joanna Góralska,Bogdan Solnica
Małgorzata Pokrywka
Cannabis has been cultivated by man since Neolithic times. It was used, among others for fiber and rope production, recreational purposes and as an excellent therapeutic agent. The isolation and characterization of the structure of one of t...
Izabela Bronikowska,Elżbieta Świętochowska,Mariusz Oleksiak et al.
Izabela Bronikowska et al.
Altered glycosylation is a universal characteristic of cancer cells, and various types of glycan structures are well‑known markers of tumor progression and invasion. The present article discusses this aspect of the role of sialic acid, bio...
Agnieszka Rusak,Karolina Jabłońska,Piotr Dzięgiel
Agnieszka Rusak
YKL-40 is a secretory protein secreted among others by tumor cells and tumor-associated macrophages. Due to the structural homology this protein was classified to chitinases family CLP (chitinase - like protein) and to 18 of glycosyl hydrol...
Małgorzata Zbrojkiewicz,Leszek Śliwiński
Małgorzata Zbrojkiewicz
Intracellular concentration of cGMP depends on the activity of guanylate cyclase, responsible for its synthesis, on the activity of cyclic nucleotide degrading enzymes - phosphodiesterases (PDEs). There are two forms of guanylate cyclase: t...
Retinol-binding protein 4 (RBP4) as the causative factor and marker of vascular injury related to insulin resistance [0.03%]
视黄醇结合蛋白4(RBP4)是与胰岛素抵抗相关血管损伤的致病因子和标志物
Marcin Majerczyk,Magdalena Olszanecka-Glinianowicz,Monika Puzianowska-Kuźnicka et al.
Marcin Majerczyk et al.
One of adipokines involved in the development of insulin resistance is retinol-binding protein 4(RBP4). The physiological role of RBP4 is transport of retinol from the liver to peripheral tissues. One of the first events related to the exce...
Katarzyna Krysztopa-Grzybowska,Anna Lutyńska
Katarzyna Krysztopa-Grzybowska
Tuberculosis was, and still is, one of the main causes of morbidity and mortality in the world. Thus it still remains a public health priority. Nonetheless, without a newly developed vaccine, it is rather unlikely to be easily resolved. The...
Natalia Matulewicz,Monika Karczewska-Kupczewska
Natalia Matulewicz
Insulin resistance is a condition of reduced biological response to insulin. Growing evidence indicates the role of the chronic low-grade inflammatory response in the pathogenesis of insulin resistance. Adipose tissue in obesity is characte...
Programmed cell death - strategy for maintenance cellular organisms homeostasis [0.03%]
程序性细胞死亡-维持细胞稳态的策略
Mirosław Godlewski,Agnieszka Kobylińska
Mirosław Godlewski
Programmed cell death (PCD) is a cellular suicide process, commonly found in organisms, that is important for elimination unnecessary and damaged cells during development and adaptation to abiotic and biotic environmental stresses. PCD is a...
Katarzyna Bandurska,Agnieszka Berdowska,Małgorzata Król
Katarzyna Bandurska
For many years attempts are made to develop efficient methods for transformation of medicinal plants via Agrobacterium tumefaciens. It is a soil bacteria which possess a natural ability to infect plants in places of injures which results in...