[BNIP3 as an atypical representative of the Bcl-2 protein family. Part 1: BNIP3, a regulator of non-apoptotic programmed cell death] [0.03%]
[Bcl-2蛋白家族的非常规代表——BNIP3及其调控非凋亡性程序化细胞死亡的作用（一）]
Ewelina Swoboda,Leon Strzadała
Ewelina Swoboda
BNIP3 is classified as a member of the Bcl-2 protein family that regulates programmed cell death and of the BH3-only protein subfamily as it only contains one BH domain. However, the transmembrane domain of BNIP3 is involved in at least som...
Ireneusz Całkosiński,Maciej Dobrzyński,Monika Całkosińska et al.
Ireneusz Całkosiński et al.
The intensity of an inflammatory response in a tissue or an organ is dependent on the efficiency of the organism's homeostatic mechanisms, which restrict the extent of the reaction. The type of factor inducing a inflammatory response and it...
Beata Polińska,Joanna Matowicka-Karna,Halina Kemona
Beata Polińska
Inflammatory bowel disease includes ulcerative colitis and Crohn's disease. It is a group of chronic disorders of unknown etiology characterized by inflammation of the gastrointestinal tract. The etiopathogenesis of inflammatory bowel disea...
[Radiation-induced bystander effect: the important part of ionizing radiation response. Potential clinical implications] [0.03%]
辐射诱导旁观者效应：电离辐射反应的重要组成部分及潜在临床意义
Maria Wideł,Waldemar Przybyszewski,Joanna Rzeszowska-Wolny
Maria Wideł
It has long been a central radiobiological dogma that the damaging effects of ionizing radiation, such as cell death, cytogenetic changes, apoptosis, mutagenesis, and carcinogenesis, are the results of the direct ionization of cell structur...
Dendritic epidermal T cells: their role in the early phase of ectromelia virus infection [0.03%]
树突状表皮T细胞：它们在痘病毒感染早期阶段的作用
Małgorzata Gieryńska,Ewelina Pawlak,Ada Schollenberger et al.
Małgorzata Gieryńska et al.
Introduction: Dendritic epidermal T cells (DETCs) are bone marrow-derived T lymphocytes that express a canonical gammadelta TCR and form a dense network in the murine skin. Here, we sought to determine their role during t...
Ryszard Smolarczyk,Tomasz Cichoń,Stanisław Szala
Ryszard Smolarczyk
Peptides are a novel class of anticancer agents embracing two distinct categories: natural antibacterial peptides, which are preferentially bound by cancer cells, and chemically synthesized peptides, which bind specifically to precise molec...
Increased percentage of CD8+CD28- suppressor lymphocytes in peripheral blood and skin infiltrates correlates with advanced disease in patients with cutaneous T-cell lymphomas [0.03%]
外周血和皮肤浸润中CD8+CD28-抑制性淋巴细胞的百分比增加与皮肤T细胞淋巴瘤患者的疾病进展相关
Donata Urbaniak-Kujda,Katarzyna Kapelko-Słowik,Dariusz Wołowiec et al.
Donata Urbaniak-Kujda et al.
Introduction: T cells with the CD8+CD28- phenotype are CD8+ lymphocytes with regulatory function. Their increased numbers were observed in infections, autoimmune and neoplastic diseases, and in elderly healthy individuals...
Comparative Study
Postepy higieny i medycyny doswiadczalnej (Online). 2009 Jul 21:63:355-9. DOI: 2009
Joanna Kozłowska,Joanna Jabłońska,Alicja Wiercińska-Drapało
Joanna Kozłowska
Toll-like receptors (TLRs) are part of the innate immune system. They recognize some protein, lipid, and nucleic structures that are common in microorganisms such as bacteria and viruses but not present in the human body. The stimulation of...
Waldemar M Przybyszewski,Joanna Rzeszowska-Wolny
Waldemar M Przybyszewski
Aging, significant impairment of the oxidation/reduction balance, infection, and inflammation are recognized risk factors of benign hyperplasia and prostate cancer. Chronic symptomatic and asymptomatic prostate inflammatory processes genera...
Agnieszka Klonowska-Szymczyk,Anna Wolska,Ewa Robak
Agnieszka Klonowska-Szymczyk
TLRs (Toll-like receptors) are found in many different vertebrate and invertebrate species. TLRs have important functions in cell activation of the nonspecific immune response as well as in the indirect specific immune response. These recep...