CRISPR/Cas9-Induced Fam83h Knock-out Leads to Impaired Wnt/β-Catenin Pathway and Altered Expression of Tooth Mineralization Genes in Mice [0.03%]
CRISPR/Cas9诱导的Fam83h基因敲除导致小鼠Wnt/β-连环素通路受损及牙齿矿化基因表达改变
Sherko Nasseri,Sara Parsa,Zakaria Vahabzadeh et al.
Sherko Nasseri et al.
Background: Dental enamel formation is a complex process that is regulated by various genes. One such gene, Family With Sequence Similarity 83 Member H (Fam83h), has been identified as an essential factor for dental ename...
Aliakbar Haddad-Mashadrizeh,Mahdi Mirahmadi,Mohammad Ehsan Taghavizadeh Yazdi et al.
Aliakbar Haddad-Mashadrizeh et al.
Context: Although for a long time, it was thought that intervening sequences (introns) were junk DNA without any function, their critical roles and the underlying molecular mechanisms in genome regulation have only recent...
Molecular Identification of Juglans Regia Endophyte LTL-G3, Its Antifungal Potential and Bioactive Substances [0.03%]
核桃内生菌LTL-G3的分子鉴定及其抗真菌潜力和生物活性物质研究
Yuanru Hao,Jianchao Hui,Tianyu Du et al.
Yuanru Hao et al.
Background: Endophyte is one of the potential biocontrol agents for inhibiting plant pathogens. However, the mechanisms and characteristics involved in the inhibition of different phytopathogenic fungi by endophytes, espe...
Identification of a New Compound (4-Fluoro-2-Trifluoromethyl Imidazole) Extracted from a New Halophilic Bacillus aquimaris Strain Persiangulf TA2 Isolated from the Northern Persian Gulf with Broad-Spectrum Antimicrobial Effect [0.03%]
从里海分离出的一种新的嗜盐Bacillus aquimaris菌株Persiangulf TA2中提取的一种新型化合物(4-氟-2-三氟甲基咪唑)的鉴定及其广谱抗菌效果
Sara Taghavi,Effat Abbasi Montazeri,Roya Zekavati et al.
Sara Taghavi et al.
Background: The unique ecosystem of the Persian Gulf has made it a rich source of natural antimicrobial compounds produced by various microorganisms, especially bacteria, which can be used in the treatment of infectious d...
Enhancement of Essential Oil Production and Expression of Some Menthol Biosynthesis-Related Genes in Mentha piperita Using Cyanobacteria [0.03%]
蓝藻提高薄荷油产量及薄荷脑生物合成相关基因的表达
Ali Akbar Ghotbi-Ravandi,Zeinab Shariatmadari,Hossein Riahi et al.
Ali Akbar Ghotbi-Ravandi et al.
Background: Mentha piperita L. is one of the most important aromatic crops and is cultivated worldwide for essential oils (EOs). Objectives: ...
Isolation, Identification, and Characterization of the Native Yeast Strains from Homemade Cheese to Assess their Eliminating Impact on the Aflatoxin B1 and M1 of the Simulated Gastrointestinal Fluid [0.03%]
自制奶酪中本土酵母菌株的分离鉴定及其对模拟胃肠液中黄曲霉毒素B1和M1消除效果的影响研究
Ghazal Yahyapour,Seyed Amir Ali Anvar,Maryam Ataee et al.
Ghazal Yahyapour et al.
Background: The occurrence of aflatoxins in food products is a silent threat to human health worldwide. A range of strategies has been introduced to address the bioavailability of aflatoxins, which are considered microbia...
Evaluating and Validating Sunflower Reference Genes for Q-PCR Studies Under High Temperature Condition [0.03%]
高温条件下利用定量PCR研究评价并向日葵参考基因验证
Masood Soltani Najafabadi,Nazanin Amirbakhtiar
Masood Soltani Najafabadi
Background: Q-PCR is the method of choice for PCR- based transcriptomics and validating microarray-based and RNA-seq results. Proper application of this technology requires proper normalization to correct as much as possi...
Inhibition of NO Production in LPS-Stimulated Primary Rat Glial Cells by Gnidilatimonoein and Extract of Daphne mucronata [0.03%]
Daphne mucronata 提取物主要活性成分gnidilatimonoein抑制LPS刺激的大鼠原代脑胶质细胞NO生成的作用及机制研究
Elham Bahrami Salehloo,Farzaneh Sabouni,Manijeh Mianabadi
Elham Bahrami Salehloo
Background: In the CNS, glial cells are involved in neuroinflammation and neuropathic pain. The glial cells are activated by a variety of pathological conditions and release pro-inflammatory mediators, including nitric ox...
Construction of an STK11 Mutation and Immune-Related Prognostic Prediction Model in Lung Adenocarcinoma [0.03%]
构建肺腺癌STK11突变和免疫相关的预后预测模型
Bo Tang,Xia Zhao,Hongbing Liu et al.
Bo Tang et al.
Background: STK11 mutation in LUAD affects immune cell infiltration in tumor tissue, and is associated with tumor prognosis. Objective: ...
Molecular Dynamics Simulation of Antimicrobial Peptide CM15 in Staphylococcus Aureus and Escherichia coli Model Bilayer Lipid [0.03%]
金黄色葡萄球菌和大肠杆菌模型双层脂质中抗菌肽CM15的分子动力学模拟研究
Davood Zaeifi,Ali Najafi,Reza Mirnejad
Davood Zaeifi
Background: In animals and plants, antimicrobial peptides (AMPs) are crucial components of defense mechanisms, as they play a crucial role in innate immunity, which protects hosts from pathogenic bacteria. The CM15 has at...