Time and Cost-Effective Genome Editing Protocol for Simultaneous Caspase 8 Associated Protein 2 Gene Knock in/out in Chinese Hamster Ovary Cells Using CRISPR-Cas9 System [0.03%]
基于CRISPR-Cas9系统的 CHO 细胞Caspase 8 蛋白关联蛋白2基因敲除/敲入的一站式高效方案
Soofia Sorourian,Abbas Behzad Behbahani,Mohsen Forouzanfar et al.
Soofia Sorourian et al.
Background: CHO cells are preferred for producing biopharmaceuticals, and genome editing technologies offer opportunities to enhance recombinant protein production. Targeting apoptosis-related genes, such as Caspases 8-As...
Antimicrobial Activity of Chitosan Scaffold Loaded with Soluble Factors of Different Probiotic Strains Against Multidrug Resistant Pseudomonas aeruginosa [0.03%]
负载不同益生菌株可溶性因子的壳聚糖支架对多重耐药铜绿假单胞菌的抗菌活性研究
Firooze Soleymani,Hamid Reza Rahimi,Hadi Farsiani et al.
Firooze Soleymani et al.
Background: Bacterial infection remains the most frequent complication of burn injury, which can lead to sepsis, even if antibiotics are used topically and systemically. Pseudomonas aeruginosa (P. aeruginosa) is the main ...
Efficient Induction of Apoptosis in Lung Cancer Cells Using Bismuth Sulfide Nanoparticles [0.03%]
用于肺癌细胞高效诱导凋亡的硫化铋纳米粒子
Leila Nasehi,Hamed Rezaeejam,Hossein Danafar et al.
Leila Nasehi et al.
Background: The use of nanomaterial-based radiosensitizers to improve the therapeutic ratio has gained attraction in radiotherapy. Increased radiotoxicity applied to the tumor region may result in adverse impact on the un...
Controlling Tomato Fusarium Wilt Disease through Bacillus thuringiensis-Mediated Defense Primining [0.03%]
一种通过苏云金芽孢杆菌介导的防御 priming 控制番茄萎黄病的方法
Zahra Kiani Dehkian,Hengameh Taheri,Babak Pakdaman Sardrood et al.
Zahra Kiani Dehkian et al.
Background: Fusarium wilt caused by the fungus Fusarium oxysporum f. sp. lycopersici (Fol) (Sacc.) W.C. Snyder and H.N. Hans is one of the most prevalent and devastating diseases of tomato plants (Solanum lycoprsicum L.) ...
Growing Conditions and Varietal Ecologies Differently Regulates the Growth-regulating-factor (GRFs) Gene Family in Rice [0.03%]
生长条件和品种生态系统分别调节水稻生长调节因子(GRFs)基因家族的表达
Raj Kishore Sahoo,Kishor Pundlik Jeughale,Suman Sarkar et al.
Raj Kishore Sahoo et al.
Background: Growth-regulating factors (GRFs) are crucial in rice for controlling plant growth and development. Among the rice cultivation practices, aerobic methods are water efficient but result in significant yield redu...
Network Cluster Analysis of PPI and Phenotype Ontology for Type 1 Diabetes Mellitus [0.03%]
基于PPI和表型本体的一型糖尿病网络聚类分析
Davood Zaeifi,Mahnaz Azarnia
Davood Zaeifi
Background: Our knowledge of Type 1 Diabetes Mellitus (T1DM) etiology is incomplete; however, the pathogenesis of the disease includes T-cell-mediated destruction of β-cells. ...
Data-Mining of Barley to Identify Salt Stress Hub Genes, Gene Expression Analysis and Recombinant Plasmid Construction [0.03%]
数据挖掘 barley以识别盐胁迫中心基因，基因表达分析和重组质粒构建
Ehsan Sohrabi,Masoud Tohidfa,Asadolah Ahmadikhah et al.
Ehsan Sohrabi et al.
Background: Salinity is one of the major abiotic stresses that limit the production and yields of agricultural crops worldwide. Objectives: ...
SOX2 Overlapping Transcript (SOX2-OT) Enhances the Lung Cancer Malignancy Through Interaction with miR-194-5p/ SOX5 Axis [0.03%]
SOX2重叠转录本（SOX2-OT）通过与miR-194-5p/SOX5轴相互作用增强肺癌恶性程度
Zahra Sadeghi,Fatemeh Dodangeh,Jamshid Raheb
Zahra Sadeghi
Background: Lung cancer is one of the most common types of cancer and a leading cause of cancer-related deaths worldwide. Therefore, it is useful to know the biomarkers involved in the malignancy of lung cancer. ...
Cloning, Prokaryotic Expression and Functional Characterization of NifH Gene from the Associative Nitrogen-Fixing Bacteria Klebsiella Variicola DX120E [0.03%]
共生固氮菌DX120E中的NifH基因的克隆、原核表达及功能分析
Ying Qin,Yu-Yan Huang,Qaisar Khan et al.
Ying Qin et al.
Background: Biological nitrogen fixation (BNF) is a unique mechanism in which microorganisms utilize the nitrogenase enzyme to catalyze the conversion of atmospheric nitrogen (N2) to ammonia (NH3). Fe protein, encoded by ...
In vitro Gluten Degradation Using Recombinant Eurygaster Integriceps Prolyl Endoprotease: Implications for Celiac Disease [0.03%]
使用重组Eurygaster Integriceps麦醇溶蛋白内切蛋白酶进行体外麦醇溶蛋白降解：对乳糜泻的启示
Effat Noori,Mojgan Bandehpour,Mohammad Reza Zali et al.
Effat Noori et al.
Background: Celiac disease (CD) is a gluten-sensitive chronic autoimmune enteropathy. A strict life-long gluten-free diet is the only efficient and accepted treatment until now. However, maintaining a truly gluten-free st...