DNA Methyltransferase Inhibition by RG108 Improves Stemness and Multipotential Differentiation of Human Adipose Tissue-derived Stem Cells [0.03%]
RG108通过抑制DNA甲基转移酶提高人脂肪组织来源干细胞的自我更新能力和多向分化能力
Razieh Asgharian,Afrooz Hashemi,Arash Javeri et al.
Razieh Asgharian et al.
Background: DNA methylation plays important roles in regulating various biological processes, including self-renewal, differentiation and regenerative capacity of stem cells. Previous studies have demonstrated that lineag...
Docking-Based Virtual Screening Method for Selecting Natural Compounds with Synergistic Inhibitory Effects Against Cancer Signalling Pathways Using a Multi-Target Approach [0.03%]
基于对接的虚拟筛选方法在多重靶点水平上选取对癌症信号通路具有协同抑制作用的天然化合物
Negar Sardarpour,Zahra Goodarzi,Sajjad Gharaghani
Negar Sardarpour
Objectives: This study aims to introduce a methodology for identifying medicinal plants that contain effective natural compounds with the most possible synergistic effects to inhibit cancer survival and proliferation in a...
Increased Expression Level of Human Blood Clotting Factor VIII Using NS0 Cell Line as a Host Cells [0.03%]
用NS0细胞作为宿主细胞提高人凝血因子VIII的表达水平
Mahboobeh Zarei,Elaheh Ferdosi-Shahandashti,Mohsen Badalzadeh et al.
Mahboobeh Zarei et al.
Background: Coagulation factor VIII (FVIII) is applied for spontaneous hemorrhaging inhibition and excessive bleeding after trauma in patients with hemophilia A. High-quality human recombinant factor VIII (rFVIII) has bee...
In-Silico Method for Predicting Pathogenic Missense Variants Using Online Tools: AURKA Gene as a Model [0.03%]
一种利用在线工具预测致病错义变异的In-silico方法：以AURKA基因为模型
Eric Jonathan Maciel-Cruz,Luis Eduardo Figuera-Villanueva,Liliana Gómez-Flores-Ramos et al.
Eric Jonathan Maciel-Cruz et al.
Background: In-silico analysis provides a fast, simple, and cost-free method for identifying potentially pathogenic single nucleotide variants. Objective:...
Recent Advances in Development of Biosensors for Monitoring of Airborne Microorganisms [0.03%]
监测空气中微生物的生物传感器最新研究进展
Zahra Mousavian,Ensieh Fahimi-Kashani,Vahidreza Nafisi et al.
Zahra Mousavian et al.
Background: The early detection of infectious microorganisms is crucial for preventing and controlling the transmission of diseases. This article provides a comprehensive review of biosensors based on various diagnostic m...
Silver Nanoparticles as Catalysts of Foeniculum vulgare L. Callus Formation and Its Content of Vitamins and some Fatty Acids [0.03%]
银 nanoparticles 对Foeniculum vulgare L.愈伤组织诱导及其中维生素和部分脂肪酸含量的影响
Anwaar Fakhre Al-Taee,Hikmat Mustafa Masyeb,Safaa M Bilal et al.
Anwaar Fakhre Al-Taee et al.
Background: Plants are a precious resource of a wide range of secondary metabolites, that are benefitted as flavours, pharmaceuticals, colours, colognes, food additives and also biopesticides. ...
Beauveria Bassiana Amylase-Polygalacturonase Production Using Lignocellulosic Biomass and Application in Juice Processing [0.03%]
一种利用木质纤维素生物质生产青霉菌淀粉酶-果胶酶并应用于果汁加工的新方法
Ayodeji Amobonye,Prashant Bhagwat,Suren Singh et al.
Ayodeji Amobonye et al.
Background: The search for sources of industrial biocatalysts, which are non-pathogenic and can utilise cheap nutrient sources, has been a continuous endeavour in the ~ 7 billion USD enzyme industry. Beauveria bassiana, a...
Recombinant Expression and Functional Assessment of Uricase from a Pertinent Origin of the Enzyme, Streptomyces sp. Strain 17-1 [0.03%]
尿酸酶的重要来源链霉菌17-1产生尿酸酶的异源表达及活性鉴定研究
Mohaddeseh Nasir Shirazi,Sajjad Sarikhan,Hossein Ghafouri et al.
Mohaddeseh Nasir Shirazi et al.
Background: Uricase or urate oxidase, as a therapeutic enzyme, is extensively applied to oxidize accumulated uric acid in the body to soluble form to treat related illnesses. ...
Thymoquinone Nanoparticle Induces Apoptosis and Cell Migration Retardation through Modulating of SUMOylation Process Genes in Breast Cancer Cell Line [0.03%]
补骨脂内酯纳米颗粒通过调节乳腺癌细胞系中的基因SUMO化过程诱导凋亡和抑制细胞迁移
Behnoush Sohrabi,Mohaddese Qadbeigi,Farzaneh Sabouni et al.
Behnoush Sohrabi et al.
Background: Due to the heterogeneity of breast cancer, most advanced-stage patients are resistant to therapy. Disruption of SUMOylation, a post-translational modification, is linked to breast cancer. ...
The Effect of Bacillus Cereus on the Ion Homeostasis, Growth Parameters, and the Expression of Some Genes of Artemisinin Biosynthesis Pathway in Artemisia Absinthium Under Salinity Stress [0.03%]
芽胞杆菌对盐胁迫下艾青蒿离子稳态、生长参数及抗疟药物青蒿素生物合成途径某些基因表达的影响
Sara Salimian Rizi,Zahra Rezayatmand,Monireh Ranjbar et al.
Sara Salimian Rizi et al.
Background: Soil salinity is a major problem in the world that affects the growth and yield of plants. Application of new and up-to-date techniques can help plants in dealing with salinity stress. One of the approaches fo...