Protein endocytosis dysfunction in kidney biopsies of patients with diabetic nephropathy and minimal change disease: a pilot study on ClC-5 and the megalin receptor [0.03%]
糖尿病肾病和微小病变型肾病患者肾活检中克隆氏症5和mekelin受体功能障碍导致蛋白质内吞异常:一项初步研究
Dorella Del Prete,Monica Ceol,Elena Sgrò et al.
Dorella Del Prete et al.
Background: Diabetic nephropathy (DN) is a major cause of chronic kidney disease. Proteinuria is a hallmark of DN. An active receptor-mediated pathway involving megalin and cubilin receptors and the Cl-/H+ antiporter ClC-...
Dialysis adequacy assessment in peritoneal dialysis: A survey of current practice in Australia and New Zealand [0.03%]
澳大利亚和新西兰腹膜透析充分性的评估:现行实践调查
Aruni Malaweera,Louis L Huang,Lawrence P McMahon
Aruni Malaweera
Background: Dialysis adequacy measured by small solute clearance (e.g. urea and creatinine) have shown no correlation with patient outcomes so guidelines recommend focusing on patient reported outcome measures (PROMs) in ...
Renal steatosis in the tubulointerstitial compartment in primary glomerulopathies: biopsy evidence and correlation with disease severity [0.03%]
原发性肾小球疾病的肾小管间质脂肪变性:活检证据及其与疾病严重程度的相关性
Gorkem Celebi,Ozan Sakir,Meral Uner et al.
Gorkem Celebi et al.
Background: While dyslipidemia is a well-established systemic risk factor in glomerular diseases, the clinical and histopathological relevance of compartmental intrarenal lipid deposition in primary glomerulonephritis (GN...
Efficacy and safety of finerenone with or without combination therapy in patients with non-diabetic chronic kidney disease: a real-world observational study [0.03%]
非糖尿病慢性肾病患者中菲尼拉ENUMEDIN联合治疗或单药治疗的疗效和安全性:一项真实世界观察性研究
Yanli Fang,Yun Shao,Xinyi Lin et al.
Yanli Fang et al.
Background: This study aimed to evaluate the efficacy and safety of finerenone, with or without combination therapy of sodium-glucose cotransporter-2 inhibitors (SGLT2i) or renin-angiotensin system inhibitors (RASi), in C...
Profile of a pediatric hypertensive cohort in a tertiary referral center [0.03%]
一三级转诊中心儿童高血压队列的特征分析
Lotem Weiss,Daniella Magen,Shirley Pollack
Lotem Weiss
Background: The overall prevalence of hypertension (HTN) among Israeli Jewish adolescents was reported to be 0.4% in males and 0.074% in females. The demographic characteristics of the Northern Israeli population are uniq...
Frailty in kidney transplant candidates is associated with reduced likelihood of transplantation [0.03%]
肾移植供者身体衰弱与移植减少有关
Alice Sabatino,Sara Alibrandi,Tea Dovšak et al.
Alice Sabatino et al.
Background: Kidney transplantation is the optimal treatment for kidney failure; however, it represents a major physiological stress. Frailty is a clinical syndrome also characterized by decreased physiological reserve and...
From inference to proof: nanopore sequencing confirms zoonotic Neisseria Zoodegmatis peritonitis after cat bite-related contamination in a patient on automated peritoneal dialysis [0.03%]
从推理到证明:纳米孔测序确认了家禽数码念珠菌腹膜炎是由猫咬伤污染自动腹膜透析患者后导致的动物源性 Neisseria zoodegmatis 腹膜炎
Nattapat Anuduang,Talerngsak Kanjanabuch,Piyaporn Towannang et al.
Nattapat Anuduang et al.
Peritoneal dialysis (PD)-associated peritonitis caused by zoonotic pathogens is uncommon and diagnostically challenging. Neisseria zoodegmatis, a Gram-negative coccobacillus residing in the oral flora of cats and dogs, has been reported onl...
Lp(a) in chronic kidney disease: state of the art and management perspectives [0.03%]
慢性肾脏病患者Lp(a)的研究进展和管理展望
Leonardo Spatola,Rosario Maccarrone,Matthias Zeiler et al.
Leonardo Spatola et al.
Patients with chronic kidney disease (CKD) exhibit a higher cardiovascular risk compared to the general population, due to CKD itself and its associated metabolic disorders, such as dyslipidemia. While statin-based management is the current...
Real-world management of dialysis-requiring acute kidney injury in Italy: a national survey of nephrology centers [0.03%]
意大利全国范围内的肾病中心关于急性肾损伤的管理调查:需要血液透析患者的护理经验
Erika Naso,Paolo Fabbrini,Marita Marengo et al.
Erika Naso et al.
Background: Dialysis-requiring acute kidney injury (AKI-D) is a frequent and severe in-hospital complication associated with high mortality, long-term kidney sequelae, and substantial resource use. National data on AKI-D ...