Establishing a Clinical Trial Quality Team in a Comprehensive Cancer Center: A Strategy to Navigate the New European Regulatory Landscape [0.03%]
在全面癌症中心建立临床试验质量团队：应对新欧洲监管环境的策略
Francesco Callegarin,Elisa Masetto,Beatrice Basaldella et al.
Francesco Callegarin et al.
Background: Clinical research has evolved into a multidisciplinary field integrating Medical Devices (MD), In Vitro Diagnostics (IVD), and Artificial Intelligence (AI), governed by a modernized European regulatory framewo...
Evaluation of Diagnostic Performance and Inter-Reader Agreement of Prostate Imaging After Focal Ablation (PI-FAB) on Post-Focal Therapy (FT) Magnetic Resonance Imaging (MRI) [0.03%]
焦点消融治疗后前列腺磁共振成像(PI-RADS V2.1)的诊断效能和阅片人之间的一致性评估研究
Guanqi Hang,Zhuyi Rebekah Lee,Anna Lois Lai et al.
Guanqi Hang et al.
Focal therapy (FT) for localized prostate cancer induces architectural changes that complicate post-treatment multiparametric magnetic resonance imaging (mpMRI) surveillance. The Prostate Imaging after Focal Ablation (PI-FAB) system was dev...
NGS-Based Genomic Profiling Identifies Independent Predictors of Time to Castration Resistance in Hormone-Sensitive Prostate Cancer: A Retrospective Real-World Study [0.03%]
基于NGS的基因组分析确定了影响激素敏感性前列腺癌患者去势抵抗时间的独立预测因子：一项回顾性的真实世界研究
Merve Turan,Merve Çırak Balta
Merve Turan
The prognostic significance of next-generation sequencing (NGS) findings during the hormone-sensitive phase of prostate cancer remains incompletely characterized. This retrospective cohort study included 92 patients who underwent NGS analys...
Assessing Immune Fitness in Oncological Rehabilitation-Validity and Responsiveness of the Immune Status Questionnaire and Single-Item Scale [0.03%]
肿瘤康复中免疫功能的评估——免疫状况问卷和单一指标量表的有效性和敏感性分析
Anne M S de Hoop,Johanna A Eggink,Cindy Veenhof et al.
Anne M S de Hoop et al.
Background: Immune fitness (IF) reflects the body's ability to mount appropriate immune responses. Monitoring IF could improve tailored treatment in oncological rehabilitation. The Immune Status Questionnaire (ISQ) and th...
Parotid Metastases from Head-Neck Cutaneous Squamous Cell Carcinoma: A Prognostic Stratification [0.03%]
来自头颈部皮肤鳞状细胞癌的耳下腺转移：预后分层
Giulia Togo,Luca Calabrese,Giovanni dell&#x;Aversana Orabona et al.
Giulia Togo et al.
Background/objectives: Cutaneous squamous cell carcinomas (cSCC) of the head and neck district are among the most common non melanocytic malignant skin carcinomas. The proposal to differentiate, within the N stage, paroti...
Access to Guideline-Concordant Oncology Genomic Testing: A Qualitative Study of Black Cancer Patients and Oncology Providers [0.03%]
符合指南的肿瘤基因检测的获取情况——一项关于黑色人种癌症患者和肿瘤科提供者的定性研究
Andrea Thoumi,Yadurshini Raveendran,Laura Fish et al.
Andrea Thoumi et al.
Genomic testing is a key component of precision oncology; however, Black patients receive genomic testing at lower rates. The purpose of this qualitative study was to identify individual and health system drivers of genomic testing disparit...
Exploring Key Unmet Supportive Care Needs of Adolescent and Young Adult Cancer Patients: A Qualitative Study to Inform Regional Program Development [0.03%]
探索青少年和年轻成人癌症患者主要未满足的支持性护理需求：一项定性研究，以促进地区项目发展
Sitara Sharma,Sarah Cleyn,Haydn Bechthold et al.
Sitara Sharma et al.
Background: Adolescents and young adults (AYAs; aged 15-39) diagnosed with cancer face distinct challenges that are poorly addressed within traditional cancer care models. This qualitative study explored AYAs' unmet supportive cancer care n...
Parsa Alan,Marie-Odile Parat
Parsa Alan
Opioids are frequently prescribed for cancer pain management, yet accumulating evidence suggests that opioid exposure may be associated with inferior outcomes in patients also undergoing treatment with immune checkpoint inhibitors (ICIs). T...
Laparoscopically Harvested Pedicled Omental Flap in Immediate Unilateral Breast Reconstruction: A Systematic Review of Surgical Techniques and Clinical Outcomes [0.03%]
腹腔镜下取膜的带蒂网膜皮瓣即刻单侧乳房重建：系统评价手术技术及临床疗效研究
Annie M Wu,Surabi Thirugnanasampanthar,Muriel Brackstone
Annie M Wu
Laparoscopically harvested pedicled omental flap (LHPOF) reconstruction is a minimally invasive autologous option for immediate breast reconstruction, but prior reviews have largely examined omental flaps broadly, combining open and laparos...
The Role of Tumor Debulking Surgery in Improving Survival of Patients with Head and Neck Cancer: A Systematic Review [0.03%]
肿瘤减瘤手术在改善头颈部癌症患者生存率方面的作用：系统性综述
Aris I Giotakis,Evangelos Tagkalos,Matthias Santer et al.
Aris I Giotakis et al.
Background/Objectives: Data on the value of tumor debulking surgery are scarce. We aimed to examine whether tumor debulking surgery followed by non-surgical treatment (cases) improves survival compared to non-surgical treatment alone (contr...