C6orf15 expression in thyroid tumors: A promising diagnostic biomarker for the classic variant of papillary thyroid carcinoma [0.03%]
甲状腺肿瘤中C6orf15的表达：经典型乳头状甲状腺癌的诊断生物标志物
Aobo Xu,Pengju Zhang,Jiaxin Chai et al.
Aobo Xu et al.
Although C6orf15 is highly expressed in certain human cancers, its expression pattern in papillary tumors remains unclear. In this study, we investigated C6orf15 expression in papillary tumors and assessed its potential as a diagnostic biom...
MPO-Mediated oxidative stress regulates lung tissue damage in T-COPD through activation of the NLRP3 inflammasome [0.03%]
MPO介导的氧化应激通过激活NLRP3炎性小体调节T型慢性阻塞性肺疾病的肺部组织损伤
Wen Li,Kaican Zong,E Jiang et al.
Wen Li et al.
Purpose: This study aimed to investigate the role of MPO in regulating the NLRP3 signaling pathway and its impact on lung injury in a Mycobacterium tuberculosis-induced chronic obstructive pulmonary disease (T-COPD) model...
Antoine Taillandier,Tristan De Nattes,Damien Sizaret et al.
Antoine Taillandier et al.
Assessment of inflammation in scarred cortical parenchyma of kidney transplant (i-IFTA) is a criterion for chronic active T cell-mediated rejection (TCMR) and has mainly been explored in one-year protocol biopsies. We evaluated the factors,...
A clinicopathological study of eight cases presenting a Biphasic structure: A distinct variant of pulmonary carcinoma [0.03%]
八例肺腺癌双相结构变异的临床病理研究
Hongyu Wang,Qiuyao Li,Jiwei Ma et al.
Hongyu Wang et al.
Biphasic structures, which are composed of outer basal cells and inner glandular cells, are frequently indicative of salivary gland-type tumors or benign lesions, such as bronchial adenoma, within the lung. However, the occurrence of a biph...
Targeting thrombin with hirudin alleviates paraquat-induced pulmonary fibrosis via the PAR-1-mediated TGF-β1 pathway [0.03%]
肝素衍生物hirudin通过PAR-1介导的TGF-β1信号通路靶向凝血酶减轻百草枯诱导的肺纤维化
Xiao Hu,Weijuan Liu,Guowen Zheng et al.
Xiao Hu et al.
Background: Paraquat (PQ)-induced pulmonary fibrosis (PF) is a serious disease without specific antidotes. Thrombin is important for promoting fibrosis development. We aimed to explore whether thrombin promotes PQ-induced...
Ronell Bologna-Molina
Ronell Bologna-Molina
Connexin 43 (Cx43) is a transmembrane protein forming gap junctions essential for intercellular communication, regulating ion and molecule exchange, and coordinating key developmental and pathological processes. In odontogenesis, Cx43 expre...
Elp3 activates the JNK/MAPK pathway through histone acetylation to promote gastric cancer proliferation, migration, and invasion [0.03%]
ELP3通过组蛋白乙酰化激活JNK／MAPK信号通路促进胃癌细胞增殖、迁移和侵袭
Ji Di,Hao Shang,Xiali Shi et al.
Ji Di et al.
Background: Gastric cancer (GC) seriously affects the life and health of patients, and the role of Elp3 in GC is still unclear; therefore, the aim of this study was to investigate the role and mechanism of Elp3 overexpres...
Comparable expression of stem markers and damage-responsive proteins in untreated and chemoradiation-treated rectal cancer [0.03%]
未经治疗和接受化学放射治疗的直肠癌中干细胞标志物和损伤反应蛋白的表达比较
Kentaro Tsuji,Sachi Sekine,Hirotoshi Kawata et al.
Kentaro Tsuji et al.
Purpose: Cancer stem cells (CSCs) are suggested to contribute to therapy resistance in rectal cancer. However, histopathological analysis of CSCs is still lacking in rectal cancer. ...
Comparable expression of stem markers and damage-responsive proteins in untreated and chemoradiation-treated rectal cancer [0.03%]
未经治疗和接受化学放射治疗的直肠癌干细胞标志物和损伤反应蛋白的可比表达研究
Kentaro Tsuji,Sachi Sekine,Hirotoshi Kawata et al.
Kentaro Tsuji et al.
Purpose: Cancer stem cells (CSCs) are suggested to contribute to therapy resistance in rectal cancer. However, histopathological analysis of CSCs is still lacking in rectal cancer. ...
Alteration in epithelium and stroma of Post-INTACS cornea: Ultrastructure and 3D transmission electron tomography [0.03%]
角膜胶原交联术后准分子激光上皮下角膜磨镶术的三维透射电子显微镜和透射电子显微镜断层扫描观察
Saeed Akhtar,Omar Kirat,Adrian Smedowski et al.
Saeed Akhtar et al.
This study was conducted to investigate the ultrastructure of the epithelium and stroma of post-INTACS corneas. INTACS were surgically inserted into the corneas of three patients to remodel the keratoconus shape. INTACS were inserted with t...