Jenny Norlin,Sara T Hjuler,Kasper Almholt et al.
Jenny Norlin et al.
Mouse and rat models of MASLD/MASH can provide valuable information about the effects of potential new treatments on liver histopathology. Liver samples for histology must therefore be representative of the entire organ, but it is also impo...
Bianca M Gregório,Carolinne R Macedo,Bruna Romana-Souza et al.
Bianca M Gregório et al.
Background: Formaldehyde remains widely used as a fixative despite its documented risks. Ethanol-based fixatives have emerged as safer alternatives, but their performance in urogenital tissues has not been systematically ...
The Kininogen 1/bradykinin receptor B2 system serves as a key molecular response of vancomycin-induced nephrotoxicity and may be a potential target of absinthin [0.03%]
Jiangying Long,Shaoshan Zhou,Cuizhi Li et al.
Jiangying Long et al.
Objective: The occurrence of nephrotoxicity induced by Vancomycin (Van) has been documented in both experimental models and clinical patients. In this study, we aimed to identify potential gene targets by utilizing Gene E...
Digital quantitative analysis of muscularis mucosae thickness in early gastric cancer specimens reveals anatomical variation [0.03%]
早期胃癌标本的数字定量分析显示固有肌层厚度存在解剖学差异
Tomoki Koike,Yukinobu Ito,Masafumi Horie et al.
Tomoki Koike et al.
The muscularis mucosae (MM) is a thin layer of smooth muscle in the gastrointestinal tract that may act as a barrier against carcinoma invasion; however, its characteristics in gastric cancer remain unclear. This study aimed to precisely me...
Myoepithelial cell cartography: A review of immunohistochemical markers in salivary gland neoplasms [0.03%]
肌上皮细胞图表：唾液腺肿瘤免疫组化标志物的综述
Carolinne Alves de Oliveira,Helen Bárbara Stamboni,Clóvis Antônio Lopes Pinto et al.
Carolinne Alves de Oliveira et al.
Myoepithelial cells (MECs) are contractile cells that exhibit both epithelial and smooth muscle characteristics. In the salivary glands, they contribute to secretion and maintenance of glandular architecture and play a fundamental role in t...
Recovery from muscle atrophy following short-term joint immobilization and non-weight-bearing after anterior cruciate ligament reconstruction in rats [0.03%]
雪旺细胞分泌的神经营养因子促进糖尿病周围神经病大鼠雪旺细胞增生及功能恢复
Akinori Kaneguchi,Marina Kanehara,Yoshika Doi et al.
Akinori Kaneguchi et al.
Previous studies have reported that joint immobilization and non-weight-bearing after anterior cruciate ligament reconstruction (ACLR) exacerbate muscle atrophy. However, it remains unclear whether the combination of these interventions wor...
The effect of intermittent fasting on liver morphology in non-alcoholic fatty liver disease: A narrative review of animal studies and clinical trials [0.03%]
间歇性断食对非酒精性脂肪肝疾病患者肝脏形态的影响：动物研究和临床试验的叙事综述
Katarzyna Piotrowska
Katarzyna Piotrowska
One of the more serious complications of obesity, apart from the development of type 2 diabetes, is the development of metabolic liver diseases, including non-alcoholic fatty liver disease (NAFLD). Intermittent fasting (IF) is one of the be...
PAQR11: An evolutionarily conserved Golgi receptor governing metabolic-immune crosstalk and systemic homeostasis [0.03%]
PAQR11：一种进化上保守的高尔基体受体，调控代谢-免疫互作及全身稳态
Yu-Zhen Zhang,Pei Li,Zhi Qiang Ling
Yu-Zhen Zhang
PAQR11, an evolutionarily conserved seven-transmembrane receptor localized at the Golgi apparatus, functions as a master coordinator of metabolic-immune integration across physiological systems. This review synthesizes cutting-edge evidence...
Xuebijing alleviates septic myocardial injury by inhibiting iron death mediated by the ICAM1/TLR signaling pathway [0.03%]
雪贝晶通过抑制ICAM1/TLR信号介导的铁死亡缓解脓毒症心肌损伤
Xiaoyan Meng,Xinming Yan,Chen Kan et al.
Xiaoyan Meng et al.
Background: Xuebijing (XBJ) has demonstrated efficacy in alleviating clinical symptoms in sepsis patients; however, its underlying mechanism requires further investigation. ...
SPI1-driven POSTN transcription promotes esophageal cancer progression and macrophage immunosuppressive polarization [0.03%]
SPI1驱动的POSTN转录促进食管癌进展和巨噬细胞免疫抑制极化
Hao Ding,Guanchu Liu,Xingqiang Ran et al.
Hao Ding et al.
Background: Esophageal cancer (EC) is a common gastrointestinal cancer with the highest mortality. Studies have suggested that macrophages play a key role in cancer progression. Increasing evidence reveals that periostin ...