Lonp1 expression and correlation with mitophagy and immune infiltration markers in colon adenocarcinoma [0.03%]
Lonp1在结肠腺癌中的表达及其与线粒体自噬和免疫浸润标志物的相关性研究
Giada Zanini,Valentina Selleri,Giorgia Sinigaglia et al.
Giada Zanini et al.
LONP1, a mitochondrial ATP-dependent protease, plays a crucial role in mitochondrial homeostasis by regulating protein turnover and mitophagy. Recent studies have highlighted its upregulation in various cancers, including colorectal cancer ...
Membranous remodeling of basal infoldings in attenuated epithelial cells of dilated renal tubules under unilateral ureteral obstruction (UUO) in adult mouse kidney [0.03%]
成人单侧输尿管梗阻(UUO)肾脏扩张肾小管上皮细胞基底折褶的膜状重塑现象
Apussara Watthanakitphibun,Suthankamon Khrongyut,Atsara Rawangwong et al.
Apussara Watthanakitphibun et al.
Under unilateral ureteral obstruction (UUO) in mouse kidneys, comparing proximal and distal tubules and collecting ducts, the distal tubules exhibited the most pronounced dilation and epithelial attenuation. Basal infoldings, typically well...
Naoluotong granules inhibit necroptosis of neural cells and improve cerebral ischemia-reperfusion injury by regulating the RIP1/NIK/IKKα/NF-κB pathway [0.03%]
脑络通颗粒通过调控RIP1/NIK/IKKα/NF-κB信号途径抑制神经元细胞坏死性凋亡改善脑缺血再灌注损伤
Yajun Li,Wei Dong,Liangyong Li et al.
Yajun Li et al.
Background: Cerebral ischemia-reperfusion can cause structural changes in brain tissue and disrupt physiological functions. Naoluotong granules (NLT) exhibit significant neuroprotective effects on brain nerve cells and ar...
Immunomodulation by collagen VI across fibrotic and tumor microenvironmental contexts [0.03%]
胶原VI蛋白在纤维化和肿瘤微环境中的免疫调节作用
Jennifer H Hammel,Sharon Gerecht
Jennifer H Hammel
The extracellular matrix (ECM) plays fundamental roles in modulating tissue structure and function under normal and pathological conditions. ECM composition is an essential consideration for studying cellular microenvironments, as varied co...
Astragalus polysaccharide protects against neuron degeneration and mitochondrial dysfunction in Parkinson's disease by upregulating CEND1 [0.03%]
黄芪多糖通过上调CEND1调节帕金森病相关神经元退变及线粒体功能损伤作用研究
Zewei Cong,Chan Li,Mengqin Sun et al.
Zewei Cong et al.
Background: Parkinson's disease (PD) is a chronic neurodegenerative disorder featuring dopaminergic neuron loss, which is associated with mitochondrial dysfunction. Astragalus polysaccharide (APS) extracted from Astragalu...
Lingli Chen,Qi Song,Lei Xu et al.
Lingli Chen et al.
Objective: To investigate the pathological diagnostic value of AHNAK2 in gallbladder carcinoma (GBC), especially in adenocarcinoma (AC). Methods: ...
Yolkin tempers inflammatory mediator release and liver pathology in experimental endotoxemia in mice [0.03%]
油酮素调节小鼠实验性内毒素血症中的炎性介质释放和肝病理损伤作用机制研究
Michał Zimecki,Jolanta Artym,Maja Kocięba et al.
Michał Zimecki et al.
Yolkin is an egg yolk-derived protein with immunoregulatory properties. In this work, yolkin was evaluated as a protective agent in endotoxemic BALB/c mice. The mice were pretreated with yolkin either orally in drinking water or intraperito...
Targeting of CDK1 and PRMT5 as a potential therapeutic combination for non-small cell lung cancer [0.03%]
CDK1和PRMT5可能是治疗非小细胞肺癌的潜在联合用药靶点
Zhanqiang Zhai,Chunwei Xu,Yonghua Min et al.
Zhanqiang Zhai et al.
Objectives: The potential treatment option of targeting protein arginine methyltransferase 5 (PRMT5) has been explored, but further investigation is required to assess the efficacy of combination therapy in non-small cell...
Club (Clara) cells in human prostate: A survival guide for conventional histologists/histopathologists [0.03%]
人前列腺中的克拉拉细胞：传统组织学/病理学家的生存指南
Dorian Dikov,Albena Fakirova,Boryana Ilcheva et al.
Dorian Dikov et al.
Broncho-pulmonary club (Clara) cells (Cc) play a protective role in the lung due to the secretion of the CC16 protein. Their normal and pathological morphology and function have long been well characterized by histologists and histopatholog...
Physiological functions of seminal vesicle secretions in male fertility [0.03%]
精囊分泌物的生理功能与男性生育力之间的关系研究进展
Ayumu Taira,Taichi Noda
Ayumu Taira
In many mammals, accessory gland secretions are ejaculated into the female reproductive tract, along with sperm, and the prostates and seminal vesicles are the main glands responsible for these secretions. Cauda epididymal sperm can efficie...