Digital quantitative analysis of muscularis mucosae thickness in early gastric cancer specimens reveals anatomical variation [0.03%]
早期胃癌标本的数字定量分析显示固有肌层厚度存在解剖学差异
Tomoki Koike,Yukinobu Ito,Masafumi Horie et al.
Tomoki Koike et al.
The muscularis mucosae (MM) is a thin layer of smooth muscle in the gastrointestinal tract that may act as a barrier against carcinoma invasion; however, its characteristics in gastric cancer remain unclear. This study aimed to precisely me...
Myoepithelial cell cartography: A review of immunohistochemical markers in salivary gland neoplasms [0.03%]
肌上皮细胞图表:唾液腺肿瘤免疫组化标志物的综述
Carolinne Alves de Oliveira,Helen Bárbara Stamboni,Clóvis Antônio Lopes Pinto et al.
Carolinne Alves de Oliveira et al.
Myoepithelial cells (MECs) are contractile cells that exhibit both epithelial and smooth muscle characteristics. In the salivary glands, they contribute to secretion and maintenance of glandular architecture and play a fundamental role in t...
Recovery from muscle atrophy following short-term joint immobilization and non-weight-bearing after anterior cruciate ligament reconstruction in rats [0.03%]
雪旺细胞分泌的神经营养因子促进糖尿病周围神经病大鼠雪旺细胞增生及功能恢复
Akinori Kaneguchi,Marina Kanehara,Yoshika Doi et al.
Akinori Kaneguchi et al.
Previous studies have reported that joint immobilization and non-weight-bearing after anterior cruciate ligament reconstruction (ACLR) exacerbate muscle atrophy. However, it remains unclear whether the combination of these interventions wor...
The effect of intermittent fasting on liver morphology in non-alcoholic fatty liver disease: A narrative review of animal studies and clinical trials [0.03%]
间歇性断食对非酒精性脂肪肝疾病患者肝脏形态的影响:动物研究和临床试验的叙事综述
Katarzyna Piotrowska
Katarzyna Piotrowska
One of the more serious complications of obesity, apart from the development of type 2 diabetes, is the development of metabolic liver diseases, including non-alcoholic fatty liver disease (NAFLD). Intermittent fasting (IF) is one of the be...
PAQR11: An evolutionarily conserved Golgi receptor governing metabolic-immune crosstalk and systemic homeostasis [0.03%]
PAQR11:一种进化上保守的高尔基体受体,调控代谢-免疫互作及全身稳态
Yu-Zhen Zhang,Pei Li,Zhi Qiang Ling
Yu-Zhen Zhang
PAQR11, an evolutionarily conserved seven-transmembrane receptor localized at the Golgi apparatus, functions as a master coordinator of metabolic-immune integration across physiological systems. This review synthesizes cutting-edge evidence...
Xuebijing alleviates septic myocardial injury by inhibiting iron death mediated by the ICAM1/TLR signaling pathway [0.03%]
雪贝晶通过抑制ICAM1/TLR信号介导的铁死亡缓解脓毒症心肌损伤
Xiaoyan Meng,Xinming Yan,Chen Kan et al.
Xiaoyan Meng et al.
Background: Xuebijing (XBJ) has demonstrated efficacy in alleviating clinical symptoms in sepsis patients; however, its underlying mechanism requires further investigation. ...
SPI1-driven POSTN transcription promotes esophageal cancer progression and macrophage immunosuppressive polarization [0.03%]
SPI1驱动的POSTN转录促进食管癌进展和巨噬细胞免疫抑制极化
Hao Ding,Guanchu Liu,Xingqiang Ran et al.
Hao Ding et al.
Background: Esophageal cancer (EC) is a common gastrointestinal cancer with the highest mortality. Studies have suggested that macrophages play a key role in cancer progression. Increasing evidence reveals that periostin ...
Glutamate signaling and transport around nodes of Ranvier and internodal myelin regions [0.03%]
节点氏节和隔髓鞘区间 glutamate信号传导和转运
José Javier Miguel-Hidalgo
José Javier Miguel-Hidalgo
The roles of glutamate as a major building block of proteins and as a key participant in numerous metabolic pathways are well established. Likewise, glutamate's function as a neurotransmitter-along with the distribution and actions of its r...
Histopathological and molecular mechanisms of multi-organ damage in heat stroke: Endothelial failure, immune crosstalk, and regulated cell death pathways [0.03%]
中暑多器官损伤的 histopathological 和分子机制:内皮功能障碍、免疫相互作用和程序性细胞死亡路径
Myoung Cheol Shin,Bo Hyun Jung,Joongbum Moon et al.
Myoung Cheol Shin et al.
Heat stroke is a life-threatening condition characterized by severe hyperthermia accompanied by central nervous system dysfunction and progressive multi-organ injury. Although rapid cooling remains the cornerstone of clinical management, ac...
Alginate gel embedding preserves antigenicity in free-floating brain sections [0.03%]
藻酸盐凝胶包埋保存自由漂浮脑切片的抗原性
Mihaela Abuzan,Andreea Cercel,Dirk M Hermann et al.
Mihaela Abuzan et al.
Free-floating cryosections are widely used in neuroanatomical and immunohistochemical studies due to their superior antigen preservation and unrestricted antibody penetration. However, long-term storage of these sections is vulnerable to fr...