Treatment patterns in patients with castration-resistant prostate cancer who received darolutamide in the ARAMIS trial in Spain: PARASEC study [0.03%]
西班牙ARAMIS试验中接受达罗特鲁胺治疗的去势抵抗性前列腺癌患者的治疗模式：PARASEC研究
Javier Puente,Rubén Campanario,David Marmolejo et al.
Javier Puente et al.
Purpose: We aimed to describe treatment patterns of patients with nonmetastatic castration-resistant prostate cancer (nmCRPC) who progressed after receiving darolutamide in a real-world setting, and according to the stand...
Characterization of immune landscape and prognostic value of IL-17-related signature in uterine corpus endometrial carcinoma [0.03%]
子宫内膜癌免疫图谱的特征及IL-17相关特征组的预后价值
Man Yu,Pei Wang,Rui Liu et al.
Man Yu et al.
Background: Interleukin-17 (IL-17) plays a crucial role in the development of uterine corpus endometrial carcinoma (UCEC), but its prognostic and therapeutic implications remain unclear. This study aimed to investigate IL...
Biochemical control and 2-year tolerability following stereotactic body radiotherapy for localized prostate cancer: a multicenter study in Spain [0.03%]
西班牙立体定向体放射治疗局部前列腺癌的生物化学控制和两年耐受性：一项多中心研究
Sigfredo Elias Romero Zoghbi,Fernando López Campos,Abrahams Ocanto et al.
Sigfredo Elias Romero Zoghbi et al.
Purpose: To assess 2-year biochemical control, radiological progression, late side effects, and survival outcomes following stereotactic body radiotherapy (SBRT) for localized prostate cancer in a multicenter Spanish coho...
Mónica Guillot Morales,Ana Fernández Montes,Julen Fernández-Plana et al.
Mónica Guillot Morales et al.
Anal cancer is rare but increasingly common, currently accounting for 2% of all digestive neoplasms. Some 50% of anal cancers are diagnosed at the localized stage, 29% as locoregional disease, and 12% as metastatic disease. When clinical su...
Interpretable deep learning model of circulating genomics for quantitative survival prediction in advanced non-small cell lung cancer [0.03%]
循环基因组学的解释性深度学习模型在晚期非小细胞肺癌患者生存预测中的应用研究
Yu Wang,Yi-Tong Li,Ming-Hao Wang et al.
Yu Wang et al.
Purpose: Accurate quantitative survival prediction in advanced non-small cell lung cancer (NSCLC) remains an unmet clinical need. While liquid biopsy is widely used, single circulating tumor DNA (ctDNA) shows limited pred...
Efficacy and safety of trilaciclib to prevent chemotherapy-induced myelosuppression in advanced solid tumors: a systematic review and meta-analysis [0.03%]
三氯倍他丁预防晚期实体瘤化疗所致骨髓抑制有效性和安全性的系统评价和meta分析
Muhammad Ahmed,Muhammad Umer,F N U Deeksha et al.
Muhammad Ahmed et al.
Background: Trilaciclib is a cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitor that has shown promise in mitigating chemotherapy-induced myelosuppression (CIM). This meta-analysis aims to provide a comprehensive and clin...
Prevalence and prognostic impact of HPV, EBV, and HIV in head and neck squamous cell carcinoma in the Brazilian Amazon cohort [0.03%]
巴西亚马逊地区头颈部鳞状细胞癌中HPV、EBV和HIV的流行率及预后影响
Alberto Mitsuyuki de Brito Kato,Francisco Cezar Aquino de Moraes,Valdenira de Jesus Oliveira Kato et al.
Alberto Mitsuyuki de Brito Kato et al.
Background: Squamous cell carcinoma of the head and neck (SCCHN) is the fifth most common cancer in the world. We investigate the general frequency of SCCHN in the Brazilian Amazon to identify the prevalence of HPV, EBV, ...
Longitudinal analysis of systemic inflammatory biomarkers in glioblastoma patients: an exploratory single‑center analysis [0.03%]
胶质母细胞瘤患者全身炎症生物标志物纵向分析：一项单中心探索性研究
Yener Şahin,Dilek Gül,Mustafa Şenses et al.
Yener Şahin et al.
Purpose: To explore the systemic inflammatory biomarker changes throughout the entire treatment period from the perspective of the extent of surgical resection and their possible role in predicting survival in glioblastom...
Futility in patients with peritoneal carcinomatosis of ovarian origin undergoing or who underwent interval cytoreductive surgery: a multicenter retrospective observational study [0.03%]
腹腔细胞减灭术后或接受过间期细胞减灭术的卵巢来源的腹膜癌患者的姑息性治疗：一项多中心回顾性观察研究
Silvia Carbonell-Morote,Alvaro Arjona-Sánchez,Pedro Antonio Cascales-Campos et al.
Silvia Carbonell-Morote et al.
Introduction: The indicators of surgical outcomes are handy tools in health management. Futility is a very interesting indicator, because it defines those patients who have undergone a surgical procedure with its morbidit...
Blood derived extracellular vesicles in patients with glioblastoma: preliminary experience from a monoinstitutional series [0.03%]
胶质母细胞瘤患者的血液源性外泌体：单一机构的初步经验
Andrea Di Cristofori,Martina Ghizzi,Francesca Raimondo et al.
Andrea Di Cristofori et al.
Purpose: Glioblastoma (GB) is the most common and aggressive primary brain tumor in adults, with its significant inter- and intra-tumoral heterogeneity being a major factor in its treatment resistance and overall prognosi...