The prognostic value of methylated ctDNA, soluble PD-L1, and NK-cell activity on the risk of relapse after curative radiotherapy of non-small cell lung cancer [0.03%]
非小细胞肺癌根治性放疗后复发风险的甲基化ctDNA、可溶性PD-L1和NK细胞活性预后的价值评估
Thomas Leth Fink,Rikke Fredslund Andersen,Cecilie Mondrup Jacobsen et al.
Thomas Leth Fink et al.
Introduction: Despite receiving curative radiotherapy (RT) for localized lung cancer, relapse may occur within the first year, and 5-year survival is low. In this study, we evaluated the prognostic ability of the combinat...
AURKB drives aggressive phenotype and clinicopathological progression in cholangiocarcinoma [0.03%]
AURKB驱动胆管癌的侵袭性表型及临床病理进展
Minglong Wang,Peipei Shang,Yanxi Luo et al.
Minglong Wang et al.
Objective: This study aimed to explore the role of AURKB (Aurora kinase B) in the progression of cholangiocarcinoma and evaluate its correlation with pathological characteristics, survival, and cellular function. ...
Challenging esophageal surgery: risk factors, outcomes, and a comparative single-center analysis [0.03%]
食管手术的风险因素、结果及单一中心比较分析
Leonardo Duranti,Luca Tavecchio,Luigi Rolli et al.
Leonardo Duranti et al.
Introduction: Esophageal cancer ranks as the eighth most common cancer among human populations and stands as the sixth leading cause of cancer-related deaths. Effective treatment of esophageal tumors necessitates a compre...
FAT4 loss promotes tumor growth and ferroptosis resistance in hepatocellular carcinoma via PI3K/AKT pathway activation [0.03%]
FAT4丢失通过激活PI3K / AKT途径促进肝细胞癌的肿瘤生长和铁死亡抵抗
Jing Li,Jialing Sun,Rui Hu et al.
Jing Li et al.
Purpose: Drug resistance in hepatocellular carcinoma (HCC) presents a substantial therapeutic challenge. Ferroptosis has emerged as a promising therapeutic strategy, yet the mechanisms underlying resistance are not fully ...
The early diagnostic value of lung cancer autoantibodies and tumor markers in lung cancer [0.03%]
肺癌自身抗体和肿瘤标志物在肺癌早期诊断中的价值分析
Yanyan Hao,Pengfei Wang,Zhiping Zhao et al.
Yanyan Hao et al.
Objective: To investigate the diagnostic value of seven lung cancer-related autoantibodies (7-AABs) and four tumor markers (4-TMs) for the early detection of lung cancer, aiming to assess their combined effectiveness comp...
Clinical experience and satisfaction in patients with advanced breast cancer participating in the abemaciclib patient support program in Spain: a prospective observational study [0.03%]
西班牙接受阿贝麦奇利治疗的晚期乳腺癌患者临床体验及满意度研究：一项前瞻性观察性研究
Isabel Blancas,Miriam González de la Peña,María Fernández Abad et al.
Isabel Blancas et al.
Purpose: To evaluate the impact of a patient support program (PSP) on the management of abemaciclib-related diarrhea in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative (HR+/HER2-...
Determinant of quality of life among colorectal cancer patients with a stoma: a single-center cross-sectional study in Egypt [0.03%]
埃及单中心横断面研究：结直肠癌造口患者的生存质量决定因素
Ahmad Mostafa,Alaa M Mostafa,Shimaa Anwer et al.
Ahmad Mostafa et al.
Background: Colorectal cancer (CRC) is considered one of the major global health concerns, often managed with surgical interventions followed by stoma creation. Although stomas are lifesaving, they can significantly affec...
Exploring the anticancer potential of epigallocatechin gallate-loaded sodium alginate nanoparticles: impact of size variation on head and neck cancer cells [0.03%]
表没食子儿茶素没食子酸酯-壳聚糖纳米粒的制备及其抗肿瘤活性研究
Faezeh Rajabzadeh,Mohadeseh Arabhalvaei,Samaneh Arab et al.
Faezeh Rajabzadeh et al.
Introduction: Head and neck cancer is a common malignancy, and its current treatments face major challenges, including recurrence, drug resistance, side effects, and high costs. Epigallocatechin gallate (EGCG) from green ...
First-line treatment efficacy and prognostic model in RAS-mutant metastatic colorectal cancer: a real-world study [0.03%]
一项关于ras突变型转移性结直肠癌一线治疗疗效及预后模型的现实世界研究
Wenfeng Yin,Xue Wu,Tuhua Li et al.
Wenfeng Yin et al.
Objective: This study aimed to construct and validate a dedicated prognostic model for patients with RAS-mutant metastatic colorectal cancer (mCRC) using real-world data from two centers and explore the differences in the...
Recommendations for selection, treatment, and follow-up in peptide receptor radionuclide therapy (PRRT) for neuroendocrine tumors: a Delphi consensus from the Galician Multidisciplinary Group on Neuroendocrine and Endocrine Tumors (GGNET) [0.03%]
肽受体放射核素治疗(NETs):加利西亚神经内分泌和内分泌肿瘤多学科组(GGNET)的德尔菲共识意见：关于选择、治疗及随访的建议
Nieves Martinez-Lago,José Manuel Cabezas Agricola,Urbano Anido Herranz et al.
Nieves Martinez-Lago et al.
Background: Peptide receptor radionuclide therapy (PRRT) is an established treatment for patients with well-differentiated gastroenteropancreatic neuroendocrine tumors (GEP-NETs) expressing somatostatin receptors (SSTR). ...